Finasteride 5 mg/day Treatment of Patterned Hair Loss in Normo-androgenetic Postmenopausal Women [PDF]
, 2013 BACKGROUND: There is no consensus on the standard treatment options for female pattern androgenetic alopecia (AGA). Efficacy of finasteride in women is controversial. The purpose of this study was to evaluate the clinical efficacy and safety of 5 mg/day
André, MC +3 more
core +1 more source
Identifying Drugs Associated With Parkinson's Disease Risk Using Machine Learning
Basic &Clinical Pharmacology &Toxicology, Volume 138, Issue 3, March 2026.ABSTRACT Machine learning (ML)–based methods have been proposed as a potential approach for identifying candidate drugs to be repurposed as disease‐modifying treatments for Parkinson's disease (PD). We applied an ML‐based signal detection method to identify drugs associated with PD and evaluated the method's generalizability.
Eeva Pylkkö +8 more
wiley +1 more source
Androgen-independent events in penile development in humans and animals. [PDF]
, 2020 The common view on penile development is that it is androgen-dependent, based first and foremost on the fact that the genital tubercle forms a penis in males and a clitoris in females.
Baskin, Laurence +6 more
core +1 more source
BJU International, Volume 137, Issue 3, Page 430-443, March 2026.Objective To critically evaluate the existing evidence base surrounding the efficacy of preoperative 5‐alpha reductase inhibitor (5ARI) administration in the reduction of perioperative complication rates in transurethral resection of prostate (TURP). Methods In April 2025, a systematic search of on‐line databases was conducted to identify randomised ...
Cian M. Hehir +5 more
wiley +1 more source
Persistent Sexual, Emotional, and Cognitive Impairment Post-Finasteride
American Journal of Men's Health, 2015 Finasteride is a synthetic 5-α reductase inhibitor, which prevents the conversion of testosterone to dihydrotestosterone and has been used for more than 20 years in the treatment of male pattern hair loss.
Christine Anne Ganzer PhD +2 more
doaj +1 more source
Topical Finasteride in Hirsutism: A Double Blind Randomized Clinical Trial on Adult Women
Journal of Research in Medical Sciences, 2005 Background: Finasteride partially blocks the conversion of testosterone to dihydrotestosterone through inhibition of 5 α- reductase in hair follicles. Finasteride cream can penetrate to dermis to arrive at hair follicle due to its solubility.
F Iraji, S Karbasioun, A Aminorroaya
doaj
Immunohistochemical evaluation of androgen receptor and nerve structure density in human prepuce from patients with persistent sexual side effects after finasteride use for androgenetic alopecia. [PDF]
PLoS ONE, 2014 Finasteride is an inhibitor of 5-α-reductase used against male androgenetic alopecia (AGA). Reported side effects of finasteride comprise sexual dysfunction including erectile dysfunction, male infertility, and loss of libido. Recently these effects were
Carla Di Loreto +5 more
doaj +1 more source
Endogenous neurosteroids influence synaptic GABAA receptors during post-natal development [PDF]
, 2017 GABA plays a key role in both embryonic and neonatal brain development. For example, during early neonatal nervous system maturation, synaptic transmission, mediated by GABA A receptors (GABA ARs), undergoes a temporally specific form of synaptic ...
Agis-Balboa +144 more
core +2 more sources
Post-finasteride syndrome: our current knowledge
Вестник урологии, 2020 5-α reductase inhibitors are effective and commonly used medications for the treatment of benign prostatic hyperplasia. However, there are some questions about the safety of such medications.
A. A. Galushkin +2 more
doaj +1 more source