Results 71 to 80 of about 33,724 (269)
Borumand M, Sibilla S. Clin Interv Aging. 2014;9:174 7– 1758. The authors noticed a mistake in their paper which was overlooked during the revision process of the paper.
Borumand M, Sibilla S
doaj
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
TOMATO BIOCHEMICAL COMPOSITION AND QUALITY ATTRIBUTES IN DIFFERENT MATURITY FRUITS
Maturity at harvest is very important attribute to tomatoes quality. This research showed that fully ripen tomato fruits had the highest amount of lycopene and β-carotene respectively 46.68 and 6.22 g kg-1.
Audrius Radzevičius +5 more
doaj
Research on the Correlation Between Skin Elasticity Evaluation Parameters and Age
This study aims to explore the impact of aging on skin elasticity, a key biomechanical property that diminishes over time, using the Cutometer to assess viscoelastic parameters.
Dandan Chen +5 more
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Three peach (‘Honora’, ‘Dr. Davis’ and ‘Fairtime’) and five nectarine (‘Maria Anna’, ‘Diamond Ray’, ‘Fairline’, ‘Nectaross’, ‘Sweet Red’) cultivars were analyzed at harvest and after a postharvest ripening period.
M. Nuzzi +4 more
doaj +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Growth, development and fruit quality blueberry (Vaccinium corymbosum L.) variety Brigitta under different shade nets were evaluated. Assays were performed in plants 7 years in a commercial orchard Collipulli, Araucanía Region, Chile.
Mario Marcelo Rodríguez Beraud +1 more
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source

