Advanced Science, EarlyView.A mechanically activated SynNotch reporter platform enables detection of force transmission through receptors as they mediate immune cell interactions. Targeting CD40 on B cells and TCR on T cells records force‐induced reporter activation across 2D coculture, 3D organoid, and implanted in mice, which also reveal force‐amplification of immune receptor ...
Menglan Li +9 more
wiley +1 more source
Microbial Protein as a novel ingredient in pet food: A food preference study in dogs and cats. [PDF]
PLoS OneMotta de Matos A, Cruz ALB.
europepmc +1 more source
One‐Step Immobilized Phage Depolymerase Coatings for Catheter‐Related Bloodstream Infections
Advanced Science, EarlyView.Catheter‐related bloodstream infections (CRBSI) caused by drug‐resistant Gram‐negative bacteria remain a major clinical challenge. Here, a polydopamine‐assisted depolymerase coating degrades bacterial capsules and restores serum‐mediated killing, effectively suppressing biofilms and reducing bacterial burden in vitro, ex vivo, and in vivo, presenting a
Lingkai Dong +11 more
wiley +1 more source
Dietary Arecoline Supplementation Enhances Flesh Quality, Muscle Growth, and Protein Deposition in Grass Carp (<i>Ctenopharyngodon idella</i>): Insights Into TOR and FOXO Signaling Pathways. [PDF]
Aquac NutrWu LQ +11 more
europepmc +1 more source
Repurposing FDA‐Approved Drugs to Inhibit Fungal PPTases for Broad‐Spectrum Synergy
Advanced Science, EarlyView.Fungal secondary metabolites serve as crucial virulence effectors; however, the potential of their biosynthetic pathways as antifungal targets remains inadequately comprehended. Repurposed FDA‐approved drugs inhibit fungal PPTase (essential for secondary metabolism) in vivo.
Zili Song +7 more
wiley +1 more source
Bias-reduced Regression Analysis in Nutrition (BRAiN) index: self-reported diet and predicted cognitive function. [PDF]
Front NutrConti F, Gluck KA, Stocco A, Wood TR.
europepmc +1 more source
Advanced Science, EarlyView.A microfluidic Herd‐Immunity‐on‐a‐Chip experimentally recreates structured contact networks to quantify viral transmission dynamics. By controlling susceptible, infected, and non‐susceptible populations, the platform reveals how contact topology governs the reproduction number, outbreak propagation, herd‐immunity–like behavior, and intervention ...
Jiande Zhang +6 more
wiley +1 more source
Mapping the Healthiness of Campus Food Environments in Nigeria: In-Store Retail and Outdoor Advertising Assessments at Selected Universities-The NigeFE Study. [PDF]
Int J Environ Res Public HealthIheme GO +10 more
europepmc +1 more source
Advanced Science, EarlyView.Deterministic crypt fission is achieved in intestinal organoids using photopatternable hydrogels with spatiotemporal control. Daughter‐crypt symmetry is shown to depend on parent‐crypt geometry and epithelial curvature, while myosin‐dependent mechanosensing links tissue shape to regenerative outcomes.
Delaney L. McNally +8 more
wiley +1 more source
A Short Questionnaire for Evaluating Mediterranean Diet Adherence and Nutritional Sustainability: Validation in Turkish Adults. [PDF]
J Hum Nutr DietRakıcıoğlu N +2 more
europepmc +1 more source