Results 211 to 220 of about 388,664 (290)

Framework for Identifying Signature Foods for Health in the Children's Healthy Living Program in the United States Affiliated Pacific Region. [PDF]

J Nutr
Wilkens LR, Dela Cruz R, Yamanaka AB, Hammond K, Shvetsov YB, Aflague T, Butel J, Coleman P, Fleming T, Shallcross L, Fialkowski MK, Young C, Ing C, Franck K, Esquivel M, Novotny R.   +15 more
europepmc   +1 more source

An Activity‐Dependent NEPAS–PTX3 Axis Links Neurovascular and Myelin Deficits to Cognitive Impairment

Advanced Science, EarlyView.
An activity‐dependent pathway links prefrontal circuit hypoactivity to cognitive impairment. Reduced PVA–mPFC activity upregulates NEPAS, which suppresses PTX3 secretion, leading to impaired angiogenesis, myelin deficits, and memory decline. Rescue is achieved by NEPAS knockdown or chemogenetic circuit activation.
Boya Hu, Zifei Chen, Bingmei Sun, Jiale Gao, Jiale Xu, Xiaochun Guo, Fenfei Gao, Zhongsi Wang, Jie Wu, Xiaoyu Ji, Peipei Liu, Bing Huang   +11 more
wiley   +1 more source

Association between dietary protein intake and frailty index among home-dwelling older adults; an 8-year follow-up study. [PDF]

J Nutr Health Aging
Bålsrud P, Ulven SM, Hjartåker A, Ottestad I, Retterstøl K, Schwab U, Christensen JJ, Thoresen M, Holven KB.   +8 more
europepmc   +1 more source

Hepatocyte BDNF Acts as a Novel Immune Checkpoint to Restrain TLR4‐Mediated Acute Hepatitis

Advanced Science, EarlyView.
This study identifies hepatocyte‐derived BDNF as an endogenous TLR4 antagonist that alleviates acute hepatitis. BDNF is downregulated in hepatocytes via REST‐mediated transcriptional repression during ALI/ALF. Mechanistically, BDNF binds to TLR4 on macrophages to suppress inflammation.
Weiwei Zhu, Yaqian Cui, Yongqiang Zhou, Yihui Zheng, Lijiang Huang, Leiming Jin, Qianhui Zhang, Pan Chen, Mengsha Lin, Jiaxi Ye, Yongqiang Xiong, Joo Young Huh, Xiang Hu, Xiaokun Li, Wu Luo, Guang Liang   +15 more
wiley   +1 more source

Dietary Supplementation With CoQ10 and Sel-Plex Mitigates the Effects of Elevated Water Temperature on Performance, Digestive Physiology, Immune Competence, and Antioxidant Balance in Rainbow Trout. [PDF]

Aquac Nutr
Dadfar MH, Imani A, Vazirzadeh A, Moghanlou KS, Jamali F.   +4 more
europepmc   +1 more source

Bioprinted Tumor Microenvironment Models Reveal Immune Evasion and Guide CAR‐NK Therapeutic Strategies

Advanced Science, EarlyView.
This study presents a 3D embedded bioprinting platform that recapitulates key stromal features of the tumor microenvironment using fibroblasts and lung‐derived ECM. The model enables functional assessment of CAR‐NK cells and provides a versatile tool to support the development of next‐generation immunotherapeutic strategies against solid tumors ...
Dahong Kim, Seona Jo, In‐Hwan Jang, Yu‐Jin Kim, Youngmee Jung, Junhyoung Ahn, Hyungjun Lim, Jae Jong Lee, Kangwon Lee, Tae‐Don Kim, Su A Park   +10 more
wiley   +1 more source

Soy Protein Concentrate Dietary Substitution and <i>Bacillus coagulans</i> Supplementation Influence the Growth Performance, Digestive Enzyme Activity, Antioxidant Capacity, Gene Expression, and Gut Microbiota of Hybrid Grouper (<i>Epinephelus fuscoguttatus</i>♀ × <i>Epinephelus lanceolatus</i>♂). [PDF]

Aquac Nutr
Yuan Y, Zhang Z, Sun D, Liu Q, Wang L, Chen Y.   +5 more
europepmc   +1 more source

Novel Vascular‐Adaptive Liquid Metal Microspheres Enable Visualized Arterial Embolization Therapy

Advanced Science, EarlyView.
We present drug‐loaded liquid metal microspheres (X‐MEN) as a novel agent for image‐guided arterial embolization. With inherent radiopacity and superior deformability, X‐MEN enables real‐time monitoring and conforms tightly to irregular vessels. This approach ensures precise, long‐lasting embolization without recanalization, addressing critical ...
Chenyu Shen, Junge Chen, Gang Zhang, Zhusheng Liu, Yichen Wan, Lei Lei, Weiyan Ren, Yanyu Zhao, Bozhang Xia, Zhiqiang Yi, Jinjin Wang, Jingwang Gao, Gen Mu, Xing‐Jie Liang, Zhijun Wang   +14 more
wiley   +1 more source

Using Expert Elicitation and Systems Mapping to Support Social Innovation in the (Blue) Food System: The Case of the UK's Plymouth Fish Finger. [PDF]

J Hum Nutr Diet
Pettinger C, Parsons K, Chavez-Ugalde IY, Hunt L, Wagstaff C.   +4 more
europepmc   +1 more source

Chemically Engineered L. reuteri Delivering αPD‐L1 and Gallium Ions via Metal‐Phenolic Networks Potentiate Anti‐Tumor Immunity and Ferroptosis

Advanced Science, EarlyView.
A multifaceted chemical strategy, integrating bacterial tropism, metal‐ion interference therapy, and immunotherapy, resulted in significant tumor regression in murine models. A pioneering paradigm for the design of biohybrid materials was established, highlighting how sophisticated chemical engineering of living systems can unlock new avenues for ...
Tingting Zhang, Mengyi Xu, Yan Zhang, Zhiwen Li, Danqing Song, Jing Pang, Ke Li, Yanxiang Wang   +7 more
wiley   +1 more source