Results 71 to 80 of about 2,508,841 (396)

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

A Phytobiotic Supersupplement From Murraya koenigii Improves Growth, Physiological Health, Skin Colour and Pattern in a Wild Ornamental Fish (Oreichthys crenuchoides) Under Captivity

Aquaculture Nutrition
Ornamental fish sector is one of the fastest growing industries in the world with an estimated market value of 18–20 billion USD. Despite its global economic significance, it suffers from several issues notably, high-cost carotenoids, inadequate seed ...
Nallaperumal Siva, Gouranga Biswas, Paramita Banerjee Sawant, Sujata Sahoo, Dilip Kumar Singh, Sweta Pradhan, Prem Kumar   +6 more
doaj   +1 more source

Dietary cholesterol promotes growth and ecdysone signalling pathway by modulating cholesterol transport in swimming crabs (Portunus trituberculatus)

Animal Nutrition, 2022
Cholesterol, as an indispensable nutrient, regulates molting and growth in crustacean. As crustaceans are unable to biosynthesize cholesterol de novo, it is central to understand how dietary cholesterol affects molting in crustaceans.
Tingting Zhu, Qicun Zhou, Zheng Yang, Yingying Zhang, Jiaxiang Luo, Xiangsheng Zhang, Yuedong Shen, Lefei Jiao, Douglas R. Tocher, Min Jin   +9 more
doaj   +1 more source

Contribution of fish to food and nutrition security in Southern Africa: challenges and opportunities in fish production

Frontiers in Nutrition
This study investigated the role of fish in addressing food and nutrition security challenges in Southern Africa, focusing on 10 countries including Angola, Zambia, Malawi, Mozambique, Namibia, Botswana, Zimbabwe, Lesotho, Eswatini, and South Africa.
Sahya Maulu, C. G. Musuka, Montshwari Molefe, Tlou Kevin Ngoepe, N. N. Gabriel, Joseph Mphande, Msumenji Phiri, Valdemiro Muhala, M. Macuiane, M. Ndebele-Murisa, O. J. Hasimuna, T. Bokhutlo, Mexford Mulumpwa, V. N. Erasmus, Wilson Jere, Chipo Hazel Dekesa, C. Mubaya, M. Baloi, J. Iitembu, Enock Siankwilimba, Lin Zhang   +20 more
semanticscholar   +1 more source

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

FEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa, Kazuhiko Higashida, Naoya Nakai   +2 more
wiley   +1 more source

Mycoprotein in enhancing growth and immunity of fish

Discover Food
Mycoprotein, a protein source derived from fungi, is being researched more and more in aquaculture for its ability to promote fish health, especially immunity, growth, and resistance to disease.
Nisha Chuphal, Mohd Ashraf Malik, Yash Khalasi, Patekar Prakash, T. Bhuvaneshwaran, Potluri Sai Kishore, Kedar Nath Mohanta   +6 more
doaj   +1 more source

Dietary choline activates the Ampk/Srebp signaling pathway and decreases lipid levels in Pacific white shrimp (Litopenaeus vannamei)

Animal Nutrition, 2023
An 8-week feeding trial was conducted in Pacific white shrimp (Litopenaeus vannamei) to evaluate the effects of dietary choline supplementation on choline transport and metabolism, hepatopancreas histological structure and fatty acid profile, and ...
Jingjing Lu, Xinyue Tao, Jiaxiang Luo, Tingting Zhu, Lefei Jiao, Peng Sun, Qicun Zhou, Douglas R. Tocher, Min Jin   +8 more
doaj   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Dietary Astaxanthin Can Promote the Growth and Motivate Lipid Metabolism by Improving Antioxidant Properties for Swimming Crab, Portunus trituberculatus

Antioxidants
This study aimed to assess the influence of varying dietary levels of astaxanthin (AST) on the growth, antioxidant capacity and lipid metabolism of juvenile swimming crabs.
Yao Deng, Shichao Xie, Wenhao Zhan, Hongyu Peng, Haiqing Cao, Zheng Tang, Yinqiu Tian, Tingting Zhu, Min Jin, Qicun Zhou   +9 more
doaj   +1 more source