Results 31 to 40 of about 83,026 (211)

Yeast Augmented Network Analysis (YANA): a new systems approach to identify therapeutic targets for human genetic diseases [v1; ref status: indexed, http://f1000r.es/3gk]

F1000Research, 2014
Genetic interaction networks that underlie most human diseases are highly complex and poorly defined. Better-defined networks will allow identification of a greater number of therapeutic targets.
David J. Wiley, Ilona Juan, Hao Le, Xiaodong Cai, Lisa Baumbach, Christine Beattie, Gennaro D'Urso   +6 more
doaj   +1 more source

How to halve ploidy : lessons from budding yeast meiosis [PDF]

, 2012
Maintenance of ploidy in sexually reproducing organisms requires a specialized form of cell division called meiosis that generates genetically diverse haploid gametes from diploid germ cells.
Arumugam, Prakash, Kerr, Gary W., Sarkar, Sourav   +2 more
core   +1 more source

Fluorescent Probes Derived from the Polyene Class of Antifungal Drugs Reveal Distinct Localization Patterns and Resistance‐Associated Vacuolar Sequestration in Candida Species

Angewandte Chemie, EarlyView.
Fluorescent probes derived from all three clinically used polyene antifungals (amphotericin B, nystatin, and natamycin) enabled direct visualization of distribution in yeast cells of various Candida species. While retaining the ergosterol‐dependent mode of action of their parent drugs, the probes revealed distinct, structure‐specific localization ...
Melissa Shbeta, Tal Kopp, Ivan Voronov, Adi Yona, Rania Hasib Afana, Shmuel Carmeli, Micha Fridman   +6 more
wiley   +2 more sources

Cellular geometry scaling ensures robust division site positioning

Nature Communications, 2019
Cells divide within a given size range and can scale across differing cell sizes but mechanisms and function remain unclear. Here the authors show, despite the current dogma of fission yeast maintaining constant width, some fission yeast can scale their ...
Ying Gu, Snezhana Oliferenko
doaj   +1 more source

Response to arsenate treatment in Schizosaccharomyces pombe and the role of its arsenate reductase activity. [PDF]

PLoS ONE, 2012
Arsenic toxicity has been studied for a long time due to its effects in humans. Although epidemiological studies have demonstrated multiple effects in human physiology, there are many open questions about the cellular targets and the mechanisms of ...
Alejandro Salgado, Ana López-Serrano Oliver, Ana M Matia-González, Jael Sotelo, Sonia Zarco-Fernández, Riansares Muñoz-Olivas, Carmen Cámara, Miguel A Rodríguez-Gabriel   +7 more
doaj   +1 more source

Rad62 protein functionally and physically associates with the Smc5/Smc6 protein complex and is required for chromosome integrity and recombination repair in fission yeast [PDF]

, 2004
Smc5 and Smc6 proteins form a heterodimeric SMC (structural maintenance of chromosome) protein complex like SMC1-SMC3 cohesin and SMC2-SMC4 condensin, and they associate with non-SMC proteins Nse1 and Nse2 stably and Rad60 transiently.
Carr, Antony, Iwasaki, H., Kawane, S., Morikawa, H., Morishita, Takashi, Shinagawa, H.   +5 more
core   +2 more sources

SWI/SNF-like chromatin remodeling factor Fun30 supports point centromere function in S. cerevisiae [PDF]

, 2011
Budding yeast centromeres are sequence-defined point centromeres and are, unlike in many other organisms, not embedded in heterochromatin. Here we show that Fun30, a poorly understood SWI/SNF-like chromatin remodeling factor conserved in humans ...
Anna T. Vetter, Beth A. Sullivan, Delphine Theodorou, Edoardo Petrini, Felix Krueger, J. Ross Miller, Konrad Paszkiewicz, Margaret R. Crawford, Mickaël Durand-Dubief, Nicholas A. Kent, Patrick Varga-Weisz, Rachael R. Harris, Rosa Maria Correra, William Ryan Will   +13 more
core   +8 more sources

Divergence of cytokinesis and dimorphism control by myosin II regulatory light chain in fission yeasts

iScience, 2023
Summary: Non-muscle myosin II activation by regulatory light chain (Rlc1Sp) phosphorylation at Ser35 is crucial for cytokinesis during respiration in the fission yeast Schizosaccharomyces pombe.
Francisco Prieto-Ruiz, Elisa Gómez-Gil, Jero Vicente-Soler, Alejandro Franco, Teresa Soto, Marisa Madrid, José Cansado   +6 more
doaj   +1 more source

Double-strand break repair and homologous recombination in Schizosaccharomyces pombe [PDF]

, 2006
In recent years our understanding of double strand break repair and homologous recombination in Schizosaccharomyces pombe has increased significantly, and the identification of novel pathways and genes with homologues in higher eukaryotes has increased ...
Ahmad, Ahmad, Ahn, Ahnesorg, Akamatsu, Assenmacher, Baumann, Boddy, Boddy, Bonatto, Bransteitter, Buck, Callebaut, Caspari, Catlett, Cervantes, Chahwan, Cheok, Connelly, Cooper, Doe, Doe, Doe, Doe, Dudasova, Farah, Farah, Ferreira, Ferreira, Fukushima, Gaillard, Goedecke, Goodwin, Grishchuk, Haber, Hartsuiker, Hefferin, Jang, Jung, Khasanov, Khasanov, Kibe, Kim, Kim, Krogh, Lambert, Laursen, Macris, Maftahi, Maftahi, Manolis, Marchetti, Martin, McGlynn, Moore, Morishita, Muris, Muris, Muris, Murray, Nakada, Nakamura, Oakley, Ono, Osman, Osman, Osman, Ostermann, Paques, Parker, Prudden, Sauvageau, Schmidt, Segurado, Shinohara, Smith, Steiner, Stewart, Sung, Suto, Szankasi, Szostak, Tarsounas, Tavassoli, Thacker, Tomita, Tomita, Tsutsui, Tsutsui, Ueno, van den Bosch, van den Bosch, Virgin, Virgin, Wang, Weterings, Whitby, Whitby, Wilson, Win, Win, You, Young   +102 more
core   +2 more sources

Advanced Protocol for Molecular Characterization of Viral Genome in Fission Yeast (Schizosaccharomyces pombe)

Pathogens
Fission yeast, a single-cell eukaryotic organism, shares many fundamental cellular processes with higher eukaryotes, including gene transcription and regulation, cell cycle regulation, vesicular transport and membrane trafficking, and cell death ...
Jiantao Zhang, Zsigmond Benko, Chenyu Zhang, Richard Y. Zhao   +3 more
doaj   +1 more source