Results 41 to 50 of about 84,111 (254)

Basic methods for fission yeast [PDF]

open access: yesYeast, 2006
AbstractThe fission yeast Schizosaccharomyces pombe is a popular model system, and has been particularly influential in studies of the cell cycle and chromosome dynamics. Despite its differences from Saccharomyces cerevisiae, the tools and methods for fission yeast are conceptually similar to those used in budding yeast.
Susan L, Forsburg, Nicholas, Rhind
openaire   +2 more sources

Double-strand break repair and homologous recombination in Schizosaccharomyces pombe [PDF]

open access: yes, 2006
In recent years our understanding of double strand break repair and homologous recombination in Schizosaccharomyces pombe has increased significantly, and the identification of novel pathways and genes with homologues in higher eukaryotes has increased ...
Ahmad   +102 more
core   +2 more sources

The Multiple Functions of Rho GTPases in Fission Yeasts

open access: yesCells, 2021
The Rho family of GTPases represents highly conserved molecular switches involved in a plethora of physiological processes. Fission yeast Schizosaccharomyces pombe has become a fundamental model organism to study the functions of Rho GTPases over the ...
Jero Vicente-Soler   +4 more
doaj   +1 more source

Rad51/Dmc1 paralogs and mediators oppose DNA helicases to limit hybrid DNA formation and promote crossovers during meiotic recombination [PDF]

open access: yes, 2014
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original ...
Lorenz, Alexander   +3 more
core   +1 more source

Fission yeast cells grow approximately exponentially [PDF]

open access: yesCell Cycle, 2018
ABSTRACTHow the rate of cell growth is influenced by cell size is a fundamental question of cell biology. The simple model that cell growth is proportional to cell size, based on the proposition that larger cells have proportionally greater synthetic capacity than smaller cells, leads to the predication that the rate of cell growth increases ...
Mary Pickering   +3 more
openaire   +2 more sources

Identification of twenty-three mutations in fission yeast Scap that constitutively activate SREBP*

open access: yesJournal of Lipid Research, 2008
The endoplasmic reticulum membrane protein SREBP cleavage-activating protein (Scap) senses sterols and regulates activation of sterol-regulatory element binding proteins (SREBPs), membrane-bound transcription factors that control lipid homeostasis in ...
Adam L. Hughes   +2 more
doaj   +1 more source

Yeast Augmented Network Analysis (YANA): a new systems approach to identify therapeutic targets for human genetic diseases [v1; ref status: indexed, http://f1000r.es/3gk]

open access: yesF1000Research, 2014
Genetic interaction networks that underlie most human diseases are highly complex and poorly defined. Better-defined networks will allow identification of a greater number of therapeutic targets.
David J. Wiley   +6 more
doaj   +1 more source

Response to arsenate treatment in Schizosaccharomyces pombe and the role of its arsenate reductase activity. [PDF]

open access: yesPLoS ONE, 2012
Arsenic toxicity has been studied for a long time due to its effects in humans. Although epidemiological studies have demonstrated multiple effects in human physiology, there are many open questions about the cellular targets and the mechanisms of ...
Alejandro Salgado   +7 more
doaj   +1 more source

Cellular geometry scaling ensures robust division site positioning

open access: yesNature Communications, 2019
Cells divide within a given size range and can scale across differing cell sizes but mechanisms and function remain unclear. Here the authors show, despite the current dogma of fission yeast maintaining constant width, some fission yeast can scale their ...
Ying Gu, Snezhana Oliferenko
doaj   +1 more source

Tpz1TPP1 SUMOylation reveals evolutionary conservation of SUMO-dependent Stn1 telomere association [PDF]

open access: yes, 2014
Elongation of the telomeric overhang by telomerase is counteracted by synthesis of the complementary strand by the CST complex, CTC1(Cdc13)/Stn1/Ten1. Interaction of budding yeast Stn1 with overhang-binding Cdc13 is increased by Cdc13 SUMOylation. Human
Ahmed, Jubed O   +6 more
core   +1 more source

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