Results 51 to 60 of about 83,026 (211)

Efficient Cell Trapping by Diffusiophoretic Transport into Dead‐End Chambers

Advanced Materials Interfaces, EarlyView.
This work introduces a method to trap cells in dead‐end microstructures using dextran diffusiophoresis. Captured cells can be further encapsulated in dextran droplets via polyethylene glycol (PEG)‐dextran aqueous two‐phase separation. The stable, controllable technique offers new opportunities in cellular biology and bio‐oriented applications ...
Chi Li, Yuxin Zhou, Jaap M. J. den Toonder, Hans M. Wyss, Sailing He   +4 more
wiley   +1 more source

New Scaling Relation for Information Transfer in Biological Networks

, 2015
Living systems are often described utilizing informational analogies. An important open question is whether information is merely a useful conceptual metaphor, or intrinsic to the operation of biological systems.
Davies, Paul, Kim, Hyunju, Walker, Sara Imari   +2 more
core   +2 more sources

REEP1 Accumulation Disrupts ER Integrity and Drives Spinal Motoneuron Degeneration in Distal Hereditary Motor Neuropathy

Advanced Science, EarlyView.
REEP1 contributes to endoplasmic reticulum (ER) shaping. Variants either cause cortical motoneuron degeneration and hereditary spastic paraplegia (HSP) or spinal motoneuron degeneration and distal hereditary motor neuropathy (dHMN). Knockout causes less complex ER structures and cortical motoneuron loss.
Andrea Bock, Mona Schurig, Miles Willoughby, Andrea Mirecki, Eric Seemann, Kateryna Lohachova, Istvan Katona, Sonnhild Mittag, Lutz Liebmann, Patricia Franzka, Mehdi Heidari Horestani, Mukhran Khundadze, Thorsten Mosler, Timothy Louie, Marianne de Visser, Marian A. J. Weterman, Michael Kiehntopf, Christian Beetz, Sandor Nietzsche, Otmar Huber, Joachim Weis, Michael M. Kessels, Ramachandra M. Bhaskara, Britta Qualmann, Ivan Đikić, Christian A. Hübner   +25 more
wiley   +1 more source

Rapid regulation of protein activity in fission yeast

BMC Cell Biology, 2008
Background The fission yeast Schizosaccharomyces pombe is widely-used as a model organism for the study of a broad range of eukaryotic cellular processes such as cell cycle, genome stability and cell morphology.
MacNeill Stuart A, Kearsey Stephen, Boye Erik, Skjølberg Henriette C, Sharom Jeffrey R, Pai Chen-Chun, Garcia Ignacio, Bøe Cathrine A, Tyers Michael D, Grallert Beáta   +9 more
doaj   +1 more source

Conservation of the COP9/signalosome in budding yeast

BMC Genetics, 2002
Background The COP9/signalosome (CSN), a multiprotein complex consisting of eight subunits, is implicated in a wide variety of regulatory processes including cell cycle control, signal transduction, transcriptional activation, and plant ...
Susan Wee, Bettina Hetfeld, Wolfgang Dubiel, Dieter A Wolf   +3 more
doaj   +2 more sources

Functional conservation of coenzyme Q biosynthetic genes among yeasts, plants, and humans. [PDF]

PLoS ONE, 2014
Coenzyme Q (CoQ) is an essential factor for aerobic growth and oxidative phosphorylation in the electron transport system. The biosynthetic pathway for CoQ has been proposed mainly from biochemical and genetic analyses of Escherichia coli and ...
Kazuhiro Hayashi, Yuki Ogiyama, Kazumasa Yokomi, Tsuyoshi Nakagawa, Tomohiro Kaino, Makoto Kawamukai   +5 more
doaj   +1 more source

Understanding the molecular mechanisms of human diseases: the benefits of fission yeasts

Microbial Cell
The role of model organisms such as yeasts in life science research is crucial. Although the baker’s yeast (Saccharomyces cerevisiae) is the most popular model among yeasts, the contribution of the fission yeasts (Schizosaccharomyces) to life science is ...
Lajos Acs-Szabo, Laszlo Attila Papp, Ida Miklos   +2 more
doaj   +1 more source

Exploring Genetic Interactions with Telomere Protection Gene pot1 in Fission Yeast

Biomolecules, 2023
The regulation of telomere length has a significant impact on cancer risk and aging in humans. Circular chromosomes are found in humans and are often unstable during mitosis, resulting in genome instability.
Masaru Ueno
doaj   +1 more source

Smc5/6: a link between DNA repair and unidirectional replication? [PDF]

, 2008
Of the three structural maintenance of chromosome (SMC) complexes, two directly regulate chromosome dynamics. The third, Smc5/6, functions mainly in homologous recombination and in completing DNA replication.
A Losada, Antony M. Carr, AR Lehmann, B Hu, D Branzei, D Ivanov, DM Sheedy, E Ampatzidou, E Unal, E Unal, EA Andrews, ES Chen, F Onoda, G De Piccoli, GJ Cost, H Morikawa, HB Lindroos, HM Verkade, I Miyabe, J Palecek, J Rouse, J Sergeant, J Torres-Rosell, J Torres-Rosell, JK Chin, Johanne M. Murray, KL Borden, KM Lee, L Strom, L Strom, MI Fousteri, MN Boddy, N Aono, PR Potts, PR Potts, PR Potts, S Pebernard, S Pebernard, SH Harvey, T de Lange, T Kobayashi, T Mengiste, T Morishita, TM Roberts, WH McDonald, WM Thorburn, X Zhao   +46 more
core   +1 more source

Adding phosphorylation events to the core oscillator driving the cell cycle of fission yeast.

PLoS ONE, 2018
Much is known about the regulatory elements controlling the cell cycle in fission yeast (Schizosaccharomyces pombe). This regulation is mainly done by the (cyclin-dependent kinase/cyclin) complex (Cdc2/Cdc13) that activates specific target genes and ...
Dania Humaidan, Frank Breinig, Volkhard Helms   +2 more
doaj   +1 more source