Results 131 to 140 of about 13,276,511 (306)
DronesThis study focuses on the distributed fixed-time fault-tolerant control problem for a network of six-degree-of-freedom (DOF) fixed-wing unmanned aerial vehicles (UAVs), which are subject to full-state constraints and actuator faults.
Jianhua Lu, Zehao Yuan, Ning Wang
doaj +1 more source
Fixed Exchange Rates and Trade [PDF]
A classic argument for a fixed exchange rate is its promotion of trade. Empirical support for this, however, is mixed. While one branch of research consistently shows a small negative effect of exchange rate volatility on trade, another, more recent ...
Michael W. Klein, Jay C. Shambaugh
core
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Semiparametric Fixed-Effects Estimator [PDF]
This paper describes the Stata implementation of Baltagi and Li's (2002) series estimator of partially linear panel data models with fixed effects. After a brief description of the estimator itself, we describe the new command xtsemipar. We then simulate
Fran�ois Libois, Vincenzo Verardi
core
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Counting Bordered and Primitive Words with a Fixed Weight
, 2004 A word w is primitive if it is not a proper power of another word, and w is unbordered if it has no prefix that is also a suffix of w. We study the number of primitive and unbordered words w with a fixed weight, that is, words for which the Parikh vector
Tero Harju, A Fixed Weight, Dirk Nowotka
core
Decomposition Algorithm in Fixed Charge Time-Space Network Flow Problems [PDF]
, 2017 A wide range of network flow problems primarily used in transportation is categorized as time-space fixed charge network flow (FCNF) problems. In this family of networks, each node is associated with a specific time and is replicated across all time ...
Dehghan Nayeri, Samineh
core
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source