Results 161 to 170 of about 10,227,314 (240)

Root‐Inspired Microneedle Patch With Interlocked Rigid‐Soft Architecture for High Tissue‐Adaptiveness

Advanced Science, EarlyView.
A root‐inspired microneedle array patch uses lattice‐based mechanical interlocking to unite rigid microneedles with a flexible substrate. The interlocked rigid–soft architecture improves interfacial bonding, supports stable adhesion on curved and wet tissues under dynamic motion, and provides a versatile platform for robust biointerfacing and future ...
Jongchan Lee, Yeongjun Song, Yonghyun Cho, Hyo In Kim, Dong‐Hyun Youn, Jinbong Park, Seungbeom Choi, Dohyun Kwon, Brian Jun Lee, Sangyul Baik   +9 more
wiley   +1 more source

Klotho‐Derived Peptide 1 Protects against Acute Kidney Injury by Directly Targeting Mitochondrial ATAD3A

Advanced Science, EarlyView.
This study uncovers that KP1, a Klotho‐derived peptide, protects the kidney against acute kidney injury, a clinical syndrome with high morbidity and mortality. KP1 enters tubular epithelial cells via endocytosis, directly interacts with the mitochondrial ATAD3A/HIGD2A complex, thereby preventing cytochrome c release, and caspases activation, and ...
Xiaoyao Zhang, Shihui Lin, Tianyu Wu, Zhixin Zhang, Hong Zhou, Xue Hong, Youhua Liu   +6 more
wiley   +1 more source

Investigating the FLASH Effect in a Rat Brain Organotypic Model With a Novel High-Energy Electron Beam. [PDF]

Int J Radiat Oncol Biol Phys
Kay TV, Price AL, Sprenger M, Radosova VJP, Thompson A, Martin EL, Dunn D, Popov V, Mikhailov S, Reitman ZJ, Wu YK, Floyd SR, Oldham M.   +12 more
europepmc   +1 more source

A Drug‐Gated, Modular STAb‐T Immunotherapy With External Control

Advanced Science, EarlyView.
Engineered STAb‐TON cells act as programmable living factories that continuously secrete inactive antibody modules, which assemble extracellularly into a functional T cell engager only upon small‐molecule administration. This externally controlled platform enables reversible, on‐demand regulation of antitumor immunity, establishing a new paradigm for ...
Susana Luengo‐Arias, Carmen Domínguez‐Alonso, Ivana Zagorac, Antonio Tapia‐Galisteo, Eva García‐Veros, Laura Rubio‐Pérez, Marina Gómez‐Rosel, Patricia Fuentes, Patricia Hernández‐López, Óscar Aguilar‐Sopeña, Laura Almagro‐Puente, Sonia Martínez‐González, Lucía Cañizares‐Moscato, María Rivas‐Sánchez, Belén Blanco, Ángel Ramírez‐Fernández, Laura Díez‐Alonso, Carmen Blanco‐Aparicio, Javier Arroyo‐Ródenas, Jorge Martínez‐Torrecuadrada, María L. Toribio, Pedro Roda‐Navarro, Anaïs Jiménez‐Reinoso, Luis Álvarez‐Vallina   +23 more
wiley   +1 more source

Ultra-intense pulsed source of ionizing radiation based on direct laser acceleration of electrons for studying the FLASH effect. [PDF]

Sci Rep
Gyrdymov M, Bukharskii N, Fabian V, Häfner M, Karoon P, Borisenko NG, Cikhardt J, Zähter S, Korneev P, Jacoby J, Andreev NE, Rosmej ON.   +11 more
europepmc   +1 more source

Operando Visualization of Cathode Water Management in Proton Exchange Membrane Water Electrolyzers Using Synchrotron X‐Ray Radiography

Advanced Science, EarlyView.
The cathode of proton exchange membrane water electrolyzers remains a poorly understood region despite its importance for hydrogen purity and operational safety. Operando synchrotron X‐ray radiography directly visualizes liquid water behavior and uncovers a transition from continuous to pulsating transport, providing new insight into multiphase ...
Wataru Yoshimune, Tetsuichiro Hayakawa, Yuta Miyase   +2 more
wiley   +1 more source

Development and characterization of phantoms to investigate the Flash effect with <i>Drosophila melanogaster</i> at an ultra-high dose rate radiotherapy linac. [PDF]

Phys Imaging Radiat Oncol
Dal Bello R, Kreuzer M, Vetrugno I, Little JC, Kranzer R, Schischke S, Bossin L, Yukihara EG, Guckenberger M, Pruschy M, Tanadini-Lang S.   +10 more
europepmc   +1 more source

Geometry‐Regulated Electrode‐Wide Nucleation Patterns in Aqueous Zinc Anodes

Advanced Science, EarlyView.
Laser‐ablated 3D hole patterning enables geometry‐driven control of Zn deposition in aqueous batteries. The hole opening ratio (HOR) governs electrode‐wide nucleation patterns by regulating the spatial distribution of nucleation sites and the evolution of early‐stage Zn deposits.
Seyoung Han, Taehyun Lee, Haeun Kim, Ji Hyun Um, Dongkyoung Lee   +4 more
wiley   +1 more source

Quantifying the flash effect and its dependence on average dose rate in vivo for 6 MeV electron and 6 MV photon beams. [PDF]

Clin Transl Radiat Oncol
Paillas S, Taylor ERJF, Lövgren N, Tullis IDC, Petersson K.   +4 more
europepmc   +1 more source

Ultra-high dose rate effect on circulating immune cells: A potential mechanism for FLASH effect? [PDF]

Radiother Oncol, 2020
Jin JY, Gu A, Wang W, Oleinick NL, Machtay M, Spring Kong FM.   +5 more
europepmc   +1 more source