Results 121 to 130 of about 7,738 (191)

FLASH radiotherapy International Workshop

Radiotherapy and Oncology, 2019
Marie-Catherine Vozenin, Michael Baumann, Rob P. Coppes, Jean Bourhis   +3 more
openaire   +6 more sources

Towards Clinical Translation: Establishing Optimal Dose and Dose-Rate Parameters for the FLASH Skin-Sparing Effect

Dose-Response
Purpose FLASH radiotherapy (FLASH-RT) has been reported to spare skin from acute radiation toxicity. However, systematic quantification is needed to determine the dose and dose-rate thresholds necessary for optimal radioprotection in FLASH radiotherapy ...
Yufeng Shen, Jie Zhou, Jinyi Lang, Lintao Li, Yongjie Li, Chenxi Yang, Shuo Wang, Xiaohua Chen, Siyu Xie, Wei Tang, Shun Lu   +10 more
doaj   +1 more source

Randomized phase II selection trial of FLASH and conventional radiotherapy for patients with localized cutaneous squamous cell carcinoma or basal cell carcinoma: A study protocol

Clinical and Translational Radiation Oncology
Background: Cutaneous basal cell carcinoma (BCC) and squamous cell carcinoma (SCC) are the most prevalent skin cancers in western countries. Surgery is the standard of care for these cancers and conventional external radiotherapy (CONV-RT) with ...
Rémy Kinj, Olivier Gaide, Wendy Jeanneret-Sozzi, Urania Dafni, Stéphanie Viguet-Carrin, Enea Sagittario, Magdalini Kypriotou, Julie Chenal, Frederic Duclos, Marine Hebeisen, Teresa Falco, Reiner Geyer, Patrik Gonçalves Jorge, Raphaël Moeckli, Jean Bourhis   +14 more
doaj   +1 more source

Comparative Transcriptomic Analysis Unveils Divergent Effects of FLASH Versus Conventional Irradiation on Skin Cells

Dose-Response
Objectives FLASH radiotherapy is garnering attention for its capacity to diminish skin toxicity without compromising tumoricidal efficacy, presenting a stark contrast to conventional (CONV) radiotherapy.
Mengmeng Xu, Qiliang Peng, Jun Zhang, Zhiming Xu, Xinyang Cheng, Zhifei Cao, Yongsheng Zhang   +6 more
doaj   +1 more source

Innovation in Radiotherapy: FLASH Therapy

Abstract FLASH radiotherapy (RT) is a new form of RT delivering the dose in milliseconds instead of minutes for conventional RT. This FLASH RT appears much less toxic on normal tissues while the effect on tumors is maintained intact or even improved for hypoxic tumors, as compared to conventional RT.
Jean Bourhis, Edouard Romano, Olivier Gaide, Veljko Grilj, Jean-Francois Germond, Till Boelhen, Raphael Moeckli, Remy Kinj   +7 more
openaire   +1 more source

Multidisciplinary approaches to the FLASH radiotherapy

Radiotherapy (RT) is extensively used in cancer treatment, although its toxicity often limits the treatment of radioresistant tumors. In this context, it has been recently shown, that irradiation at ultra-high dose rate (UHDR) (mean dose rate ≥40 Gy/s, with specific beam characteristics), called “FLASH-RT” may significantly reduce radiation-induced ...
Di Martino, Fabio, Scifoni, Emanuele, Patera, Vincenzo, Montay-Gruel, Pierre, Romano, Francesco, Darafsheh, Arash, Tozzini, Valentina   +6 more
openaire   +3 more sources

Use of apertures in single-energy pristine Bragg peak FLASH radiotherapy. [PDF]

J Appl Clin Med Phys
Ma Y, Selvaraj B, Zhao X, Cheng C, Chen CC, Diao L, Wang Y, Wang Z, Pei Y, Liu L, Yan X, Durkee B, Simone CB, Lin H, Mou X, Kang M.   +15 more
europepmc   +1 more source

FLASH Radiotherapy and Organelle-Targeted Radiosensitization in Glioblastoma: A Conceptual and Translational Review. [PDF]

Cancers (Basel)
Tang X, Wang X, Xiao K, Zhu B, Lin F, Zhou L.   +5 more
europepmc   +1 more source

Kinetic model of radiochemical oxygen depletion (ROD) in FLASH radiotherapy. [PDF]

Med Phys
Seco J, Freitas H.
europepmc   +1 more source

Organic scintillator dosimeters for flash radiotherapy: development and characterization.

FLASH radiotherapy shows a higher healthy tissues sparing compared to the conventional radiotherapy. To obtain the so-called FLASH effect the dose rate must be higher than 40 Gy/s and a dose of at least 10 Gy must be delivered in less than 200 ms.
CAVALIERI, ANDREA
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