Results 101 to 110 of about 422,772 (173)

Influence factor and mechanism of FLASH effect

Frontiers in Oncology
FLASH radiotherapy (FLASH-RT) represents an innovative treatment modality utilizing ultra-high dose-rate irradiation (>40 Gy/s). The FLASH effect, induced by FLASH-RT, is characterized by the selective radioprotective effect of normal tissue while ...
Tingyu Feng, Tingyu Feng, Tianyang He, Wentao Ye, Lisha Xiang   +4 more
doaj   +1 more source

Volumetric and Intrastructural Characterization of the Substantia Nigra Using Optimized Synthetic MR Images Derived From Quantitative T1 Maps at 3 T

NMR in Biomedicine, Volume 39, Issue 11, November 2026.
Automated segmentation using the NextBrain atlas and synthetic MRI effectively overcomes systematic age‐related biases observed in manual delineation of the substantia nigra. A novel qT1‐based synthetic contrast utilizing signal‐increased pseudo‐proton spin density (pPSD) provides improved intrastructural separation of nigral subregions (SNpc and SNpr)
Lukas von Erdmannsdorff, Lora Kovacheva, Dennis C. Thomas, Elke Hattingen, Ralf Deichmann, Christophe Théo Arendt   +5 more
wiley   +1 more source

Paraneoplastic and Autoimmune Retinopathy Presenting as Isolated Neuro‐Ophthalmic Dysfunction: Two Cases

Clinical and Experimental Neuroimmunology, Volume 17, Issue 4, November 2026.
ABSTRACT Background Paraneoplastic and autoimmune retinopathies can cause progressive visual loss before structural ophthalmic or neurologic findings are diagnostic. Case Presentation A 66‐year‐old woman developed bilateral visual decline and was diagnosed with small‐cell lung cancer‐associated paraneoplastic neuroretinal dysfunction, with persistent ...
Alan B. Dogan, Dean Neutel, Anthony L. Loschner   +2 more
wiley   +1 more source

Dosimetry characteristics of ultra-high dose rate X-ray: a short review

Frontiers in Physics
FLASH radiotherapy (FLASH-RT) has emerged as a significant area of research in the field of radiotherapy in recent years. This innovative technology delivers ultra-high dose rate radiation in a very short time, effectively damaging tumor cells while ...
Luyan Tao, Song Feng, Yiwei Yang, Bo Zheng   +3 more
doaj   +1 more source

Defining Core Functions and Forms for the Implementation of Pharmacogenomics Testing in Primary Care

Clinical and Translational Science, Volume 19, Issue 11, November 2026.
ABSTRACT Pharmacogenomics (PGx), utilizing a patient's DNA to individualize medication prescribing, minimizes adverse events and improves patient outcomes. However, the integration of PGx into primary care remains sparse. PGx testing encompasses multiple components and can be considered a complex health intervention.
Sanjana Ramesh, Larisa H. Cavallari, Victoria Wittner, Josiah Allen, Mari Angelica S. Cayabyab, Emily J. Cicali, Nihal El Rouby, Shayna R. Killam, Nita Limdi, Mohamed Nagy, Natasha Petry, April Schultz, D. Max Smith, Evangelia Eirini Tsermpini, Ron H. N. van Schaik, Ramzi G. Salloum, Sony Tuteja   +16 more
wiley   +1 more source

Unrestricted molecular motions enable mild photothermy for recurrence-resistant FLASH antitumor radiotherapy

Bioactive Materials
Ultrahigh dose-rate (FLASH) radiotherapy is an emerging technology with excellent therapeutic effects and low biological toxicity. However, tumor recurrence largely impede the effectiveness of FLASH therapy.
Hanchen Shen, Hongbin Wang, Jianlan Mo, Jianyu Zhang, Changhuo Xu, Feiyi Sun, Xinwen Ou, Xinyan Zhu, Lidong Du, Huaqiang Ju, Ruquan Ye, Guangfu Shi, Ryan T.K. Kwok, Jacky W.Y. Lam, Jianwei Sun, Tianfu Zhang, Shipeng Ning, Ben Zhong Tang   +17 more
doaj   +1 more source

Evolving role of proton therapy in contemporary oncology

Cancer, Volume 132, Issue 20, 15 October 2026.
Abstract Proton therapy offers a distinct physical advantage over photon radiotherapy through the Bragg peak dose concentration in target with both lower integral dose and finite path length, and sharper penumbra as compared to photons, collectively reducing radiation exposure to surrounding normal tissues and potentially improving the therapeutic ...
Emily S. Lebow, Helen A. Shih
wiley   +1 more source

Consensus statement on the exploration of clinical translation and application of electron ultra‐high dose rate FLASH radiotherapy

Precision Radiation Oncology
Ultra‐high dose rate FLASH Radiotherapy (FLASH‐RT) has attracted wide attention because the well‐known FLASH effect and the extremely short irradiation time.
Hui Luo, Chengliang Yang, Jinbo Yue, Hong Ge   +3 more
doaj   +1 more source

Reduced corneal toxicity following whole brain irradiation in mice

Clinical and Translational Radiation Oncology
Purpose: The emergence of focal techniques such as stereotactic radiosurgery has led to a more selective use of whole brain radiotherapy (WBRT), yet it remains an important modality for treating diffuse or multiple intracranial malignancies. During WBRT,
Vinoshene Pillai, Silvia Landi, Francesca Uccheddu, Fabio Di Martino, Andrea Cavalieri, Fabiola Paiar, Simone Capaccioli, Riccardo Cicchi, Mario Costa   +8 more
doaj   +1 more source

Exploring Design Dimensions in Flash-based Mass-memory Devices [PDF]

, 2009
Mission-critical space system applications present several issues: a typical one is the design of a mass-memory device (i.e., a solid- state recorder).
Caramia, M., Caramia M., Fabiano, Michele, Prinetto, Paolo Ernesto, Di Carlo, Stefano   +4 more
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