Results 91 to 100 of about 422,772 (173)

Exploring the role of intestinal microbiota in mitigating acute radiation-induced intestinal injury through high-energy X-ray FLASH radiotherapy via metagenomic analysis

Frontiers in Microbiology
ObjectivesThis study preliminarily examines the potential correlation between the gut microbiome and the protective effects of FLASH radiotherapy (FLASH-RT) on intestinal tissue using metagenomic analysis.MethodsCompact single high-energy X-ray source ...
Huan Du, Xiaofei Hao, Binwei Lin, Binwei Lin, Binwei Lin, Yihan Zhu, Yihan Zhu, Yihan Zhu, Yiwei Yang, Mingming Tang, Wei Wu, Decai Wang, Decai Wang, Decai Wang, Bo Lin, Bo Lin, Bo Lin, Yuwen Liang, Wenqiang Tang, Haonan Xu, Jie Li, Jie Li, Jie Li, Feng Gao, Feng Gao, Xiaobo Du, Xiaobo Du, Xiaobo Du   +27 more
doaj   +1 more source

End‐to‐end film‐based characterization of gated delivery latencies in a spot‐scanned synchrotron‐based proton therapy system

Journal of Applied Clinical Medical Physics, Volume 27, Issue 11, November 2026.
Abstract Background Temporal mismatches between gating signals and beam activation—beam‐on and beam‐off latencies—in gated particle beam therapy can compromise dose integrity. Yet standardized measurement techniques are lacking, and system‐specific characterization, particularly for synchrotron‐based proton systems, remains limited.
Z. S. Stottler, J. J. Kruse, A. J. Deisher   +2 more
wiley   +1 more source

Retrospective Chart Review Indicates Earlier Age of Endometrial Cancer Diagnosis and Elevated Housing and Transportation Vulnerability in Hispanic and Native American Populations

Cancer Medicine, Volume 15, Issue 11, November 2026.
ABSTRACT Background In 2025, Endometrial cancer (EC) is the 6th most common cancer in women globally, with rising cases in younger patients and communities of color. EC risk factors include postmenopausal status, family history, diabetes, and hyperestrogenic state conditions.
Nicole R. Jimenez, Rachel Mendoza, Erika Flores, Haiyan Cui, Paweł Łaniewski, Dana M. Chase, Denise J. Roe, Melissa M. Herbst‐Kralovetz   +7 more
wiley   +1 more source

Mechanisms of the FLASH effect: current insights and advances

Frontiers in Cell and Developmental Biology
Radiotherapy is a fundamental tool in cancer treatment, utilized in over 60% of cancer patients during their treatment course. While conventional radiotherapy is effective, it has limitations, including prolonged treatment durations, which extend patient
Giulia Rosini, Esther Ciarrocchi, Esther Ciarrocchi, Esther Ciarrocchi, Beatrice D’Orsi, Beatrice D’Orsi, Beatrice D’Orsi   +6 more
doaj   +1 more source

Association of High‐Grade Components < 20% on DFS in Stage I Lung Adenocarcinoma: A Real‐World Study of Risk Analysis and Predictive Nomogram Development

Cancer Medicine, Volume 15, Issue 11, November 2026.
ABSTRACT Objective To assess whether high‐grade components occupying < 20% of the tumor have prognostic value and whether an Adjusted Grade nomogram improves risk stratification in Stage I invasive lung adenocarcinoma (LUAD). Methods We retrospectively analyzed 1539 patients with pathologically confirmed Stage I invasive LUAD undergoing R0 resection ...
Shuhao Liang, Xuanpeng Wu, Tao Jiang, Ming Ni, Fei Xue, Chenxi Li, Tianhao Chen, Leyu Hong, Chao Luo, Qifei Wu   +9 more
wiley   +1 more source

Genomic Alterations in Pulmonary Carcinoid Tumors: A Targeted Analysis of Gene Rearrangements and Oncogenic Mutations

Cancer Medicine, Volume 15, Issue 11, November 2026.
This study applied RNA‐based next‐generation sequencing to one of the largest cohorts of pulmonary carcinoid tumors analyzed to date and revealed rare yet potentially actionable gene rearrangements and variants, including alterations in ALK, BRAF, and EGFR.
Jenni Niinimäki, Soili Kytölä, Ari Ristimäki, Johanna Arola, Tiina Vesterinen   +4 more
wiley   +1 more source

Task‐based detectability and angular‐sampling bounds on spatial resolution in cone‐beam micro‐CT: a closed‐form scan‐design analysis

Medical Physics, Volume 53, Issue 11, November 2026.
Abstract Background Spatial resolution in preclinical cone‐beam micro‐CT is conventionally characterised by image‐domain metrics measured on a specific reconstruction of a specific phantom. Such metrics conflate resolution loss originating in the data (photon noise, angular undersampling) with resolution loss originating in the reconstruction ...
Falk L. Wiegmann, Nancy L. Ford
wiley   +1 more source

Quantifying Pancreatic Fat Using a Free‐Breathing Acquisition in Adults With Obesity Undergoing Diet‐Induced Weight Loss—Results From the LION Study

NMR in Biomedicine, Volume 39, Issue 11, November 2026.
This work investigates a free‐breathing six‐echo radial stack‐of‐stars acquisition as an alternative to Cartesian breath‐hold scans for pancreatic fat quantification at 3T. In 18 participants with obesity enrolled in a randomized controlled lifestyle intervention (LION), segmented pancreatic volumes and PDFF demonstrated excellent inter‐sequence ...
Philipp Braun, Christoph Zoellner, Mingming Wu, Robert Graf, Jonathan Stelter, Anna Reik, Hans Hauner, Jan Stefan Kirschke, Christina Holzapfel, Daniela Junker, Dimitrios C. Karampinos   +10 more
wiley   +1 more source

Decrease in dose per fraction impairs the FLASH sparing effect in murine intestine model

FLASH radiotherapy (FLASH) can ease radiation-induced normal tissue toxicities; however, its benefit in clinically relevant fractionation protocols remains insufficiently explored.
Geyer, R, Devanand, P, Bailat, C, Sesink, A, Böhlen, T T, Soutter, L, Moeckli, R, Herrera, F G, Grilj, V   +8 more
core   +1 more source

Radial Tiny Golden Angle UTE (tyGA‐UTE) for Cardiac MRI in the Small Animal Model

NMR in Biomedicine, Volume 39, Issue 11, November 2026.
This study validates an 11.7‐T ultra‐high‐field tyGA‐UTE cardiac MRI workflow for murine models, featuring single‐acquisition dual reconstructions for real‐time visualization and quantitative functional assessment. It delivers performance equivalent to standard techniques, excellent reproducibility, and higher efficiency by eliminating repeated scans ...
Hao Li, Patrick Metze, Pengxi Han, Benzheng Wei, Volker Rasche   +4 more
wiley   +1 more source