Results 111 to 120 of about 7,738 (191)

Development and evaluation of an in vivo dose‐based monitoring system for electron FLASH radiation therapy

Medical Physics, Volume 53, Issue 7, July 2026.
Abstract Background FLASH radiotherapy requires further preclinical and clinical investigation to establish its biological effectiveness and define optimal beam parameters. In conventional (CONV) radiotherapy, redundant beam termination systems are a cornerstone ensuring patient safety, yet analogous safeguards for FLASH delivery are not well ...
Justin DeFrancisco, Matthew Richeson, Tomaj Javidtash, Chris Bartee, Tianjun Ma, Siyong Kim   +5 more
wiley   +1 more source

FLASH radiotherapy preserves hepatic function and maintains metabolic homeostasis in a murine breast cancer model: an experimental preclinical study

Radiation Oncology
Background Radiotherapy (RT) for treating breast cancer can result in incidental dose deposition to the liver, leading to functional impairment. FLASH radiotherapy (FLASH-RT), delivered at ultra-high dose rates (UHDR), has demonstrated remarkable normal ...
Xingyu Lu, Dehuan Xie, Liang Cui, Hang Shang, Linghong Zhou   +4 more
doaj   +1 more source

Dosimetry characteristics of ultra-high dose rate X-ray: a short review

Frontiers in Physics
FLASH radiotherapy (FLASH-RT) has emerged as a significant area of research in the field of radiotherapy in recent years. This innovative technology delivers ultra-high dose rate radiation in a very short time, effectively damaging tumor cells while ...
Luyan Tao, Song Feng, Yiwei Yang, Bo Zheng   +3 more
doaj   +1 more source

A 51‐year‐old female presenting with headache and vision loss

Headache: The Journal of Head and Face Pain, EarlyView.
Laurel Ovrom, Zachary Pardieck, Randy Christopher Bowen, Neena R. Cherayil   +3 more
wiley   +1 more source

Magnetic Resonance Imaging at 14 Tesla of Prostate Biopsies Obtained after Prostatectomy

NMR in Biomedicine, Volume 39, Issue 7, July 2026.
Fresh prostate biopsies were imaged using a 14 T vertical bore MRI scanner, and the effects of long gradient separation Δ (10–400 ms) were explored. At Δ longer than 10 ms, the percentage of voxels where the Akaike information criteria (AICc) favored a monoexponential model increased, and the apparent diffusion coefficient (ADC) lowered compared to Δ ...
Fredrik Langkilde, Stefan Kuczera, Vasiliki Spyratou, Johan Stranne, Stephan E. Maier   +4 more
wiley   +1 more source

Multi‐Omics Landscape of Paraspinal Muscles in Spinal Muscular Atrophy With Scoliosis

Journal of Cellular and Molecular Medicine, Volume 30, Issue 13, July 2026.
ABSTRACT Most spinal muscular atrophy (SMA) patients develop severe scoliosis by late adolescence. Given that the paraspinal muscles—particularly the multifidus—are indispensable for maintaining spinal stability, their site‐specific multi‐omics characteristics in SMA remain insufficiently defined. Herein, integrated multi‐omics sequencing was performed
Zhen Wang, Junduo Zhao, Xu'an Huang, Weiyun Chen, Jianxiong Shen   +4 more
wiley   +1 more source

Unrestricted molecular motions enable mild photothermy for recurrence-resistant FLASH antitumor radiotherapy

Bioactive Materials
Ultrahigh dose-rate (FLASH) radiotherapy is an emerging technology with excellent therapeutic effects and low biological toxicity. However, tumor recurrence largely impede the effectiveness of FLASH therapy.
Hanchen Shen, Hongbin Wang, Jianlan Mo, Jianyu Zhang, Changhuo Xu, Feiyi Sun, Xinwen Ou, Xinyan Zhu, Lidong Du, Huaqiang Ju, Ruquan Ye, Guangfu Shi, Ryan T.K. Kwok, Jacky W.Y. Lam, Jianwei Sun, Tianfu Zhang, Shipeng Ning, Ben Zhong Tang   +17 more
doaj   +1 more source

Faster and safer? FLASH ultra-high dose rate in radiotherapy

, 2017
Recent results from the Franco-Swiss team of Institute Curie and Centre Hospitalier Universitaire Vaudois demonstrate a remarkable sparing of normal tissue after irradiation at ultra-high dose rate (>40 Gy/s).
Marco Durante, BräUer-Krisch, Elke, Hill, Mark, Durante, Marco, Elke Brauer-Krisch, Durante, M, Brauer-Krisch, E, Mark Hill   +7 more
core   +1 more source

FLASH radiotherapy: ultra-high dose rates to spare healthy tissue

, 2019
A recent addition to the treatment options in external beam therapy, so-called FLASH radiotherapy, shows remarkable healthy-tissue-sparing properties in a number of pre-clinical studies without impacting the overall treatment efficacy.
de Kruijff, R.M., de Kruijff, R.M. (author)   +1 more
core   +1 more source

Scintillation dosimetry for FLASH radiotherapy

Radiation Measurements
The use of ultra-high dose rate (UHDR) beams for radiotherapy treatments is currently of great interest, as multiple experimental findings show that they may elicit the so-called FLASH effect, an increased sparing of normal tissues while maintaining unaltered tumour control.
Esther Ciarrocchi, Ivan Veronese
openaire   +2 more sources