Results 141 to 150 of about 5,736 (170)

Unraveling the Dual Nature of FLASH Radiotherapy: From Normal Tissue Sparing to Tumor Control.

Cancer Letters
FLASH radiotherapy (FLASH-RT), characterized by the delivery of ultra-high dose rate irradiation within microseconds to milliseconds, has rapidly emerged as a paradigm-shifting approach in radiation oncology.
Yulu Guo, Sijia Hao, Qiaozhen Huang, Cuixia Di, Lu Gan, Yi Xie, Qiang Li, Jing Si   +7 more
semanticscholar   +1 more source

FLASH Radiotherapy Mitigates Radiation-Induced Lymphopenia and Prevents Immunosuppression via Chk1-STAT3 Axis Modulation in a Preclinical Thoracic Irradiation Model

bioRxiv
Background and Aims Radiation-induced lymphopenia (RIL) is a frequent side effect of conventional radiation therapy (CONV RT), due to the high radiosensitivity of circulating lymphocytes.
Rong-Hua Tao, Kevin Liu, E. Aguilar, Min Wang, Sadhna Aggarwal, D. Neill, B. Velasquez, Sam Beddar, A. Koong, R. Mohan, E. Schüler, Steven H. Lin   +11 more
semanticscholar   +1 more source

Research Progress of Ultra-High Dose Rate Radiotherapy (FLASH-RT)

, 2020
张奇贤, 黄培根
semanticscholar   +1 more source

FLASH radiotherapy: technical advances, evidence of the FLASH effect and mechanistic insights

Biomedical engineering and physics express
Cancer is one of the leading causes of death worldwide, responsible for nearly 10 million deaths in 2020, with approximately 50% of patients receiving radiation therapy as part of their treatment (Baskar et al 2012).
M. Chaoui, O. Bouhali, Y. Tayalati
semanticscholar   +1 more source

Abstract P002: FLASH radiotherapy enhances immune activation and spares lymphocytes tumor draining lymph nodes

Clinical Cancer Research
Introduction: Conventional radiotherapy (CRT) causes antagonizing anti-tumor immune responses by depleting circulating immune cells. Given the normal tissue sparing associated with FLASH radiotherapy (FLASH-RT), we hypothesized that FLASH-RT rescues ...
F. Saenz, B. Velasquez, Abagail M. Delahoussaye, L. Connell, Nefetiti Mims, D. Neill, E. Schüler, Michael T. Spiotto   +7 more
semanticscholar   +1 more source

Female Erectile Tissues and Sexual Dysfunction After Pelvic Radiotherapy: A Scoping Review

Ca-A Cancer Journal for Clinicians, 2022
Julie R Bloom, Deborah C Marshall, Mylin A Torres   +2 more
exaly  

The Durably Antitumor Effect by FLASH Radiotherapy (FLASH-RT) Combined with Spatially Fractionated Radiotherapy (SFRT)

International Journal of Radiation Oncology, Biology, Physics
J. Zhou, S. Lu, D. Li, L. Lintao
semanticscholar   +1 more source

Towards Clinical Translation of FLASH Radiotherapy

Nature Reviews Clinical Oncology, 2022
Jean Bourhis, Marie-Catherine Vozenin, Marco Durante   +2 more
exaly  

Balancing innovation and safety in FLASH radiotherapy

Nature Reviews Physics
M. Bazalova-Carter, E. Schüler, A. Mascia, M. V. van Herk   +3 more
semanticscholar   +1 more source

Risk Factors, Pathophysiology, and Treatment of Hot Flashes in Cancer

Ca-A Cancer Journal for Clinicians, 2013
Julie Elam Otte, Menggang Yu, Gary R. Elkins   +2 more
exaly