Results 81 to 90 of about 25,781 (272)

Effects of Polyphenols on Oxidative Stress-Mediated Injury in Cardiomyocytes [PDF]

open access: yes, 2017
Cardiovascular diseases are the main cause of mortality and morbidity in the world. Hypertension, ischemia/reperfusion, diabetes and anti-cancer drugs contribute to heart failure through oxidative and nitrosative stresses which cause cardiomyocytes ...
Bei, Roberto   +10 more
core   +2 more sources

TRPM3 activation causes CGRP release in trigeminal neurons: Implications for migraine mechanisms

open access: yesHeadache: The Journal of Head and Face Pain, EarlyView.
Abstract Background The transient receptor potential melastatin 3 (TRPM3) ion channel has been implicated in sensory modulation and pain transmission and may contribute to migraine pathophysiology through calcitonin gene‐related peptide (CGRP) release in the trigeminovascular system. This study aimed to investigate TRPM3 activation and its role in CGRP
Philip V. Reducha   +9 more
wiley   +1 more source

Comparative Analysis of the Chalcone-Flavanone Isomerase Genes in Six Citrus Species and Their Expression Analysis in Sweet Orange (Citrus sinensis)

open access: yesFrontiers in Genetics, 2022
Citrus fruit contains rich nutrients which is edible and of officinal value. Citrus flavanones are widely used in the treatment of cardiovascular and other diseases, and they are a foundational material of Chinese medicine.
Quan Wan   +8 more
doaj   +1 more source

Use of Propolis chemical and Asian tiger mosquito bites : case report and review [PDF]

open access: yes, 2013
Propolis is a substance of variable composition which incorporates resins derived from plants and beeswax. It varies depending on the geographic location and local flora such as plant and bee species.
Muscat, Michelle
core  

Exploring the Phytochemical Landscape of the Early-Diverging Flowering Plant Amborella trichopoda Baill. [PDF]

open access: yes, 2019
Although the evolutionary significance of the early-diverging flowering plant Amborella (Amborella trichopoda Baill.) is widely recognized, its metabolic landscape, particularly specialized metabolites, is currently underexplored.
Chang, Lijing   +3 more
core   +1 more source

Synthesis of Deuterium-Labeled Flavanones

open access: yesChemical and Pharmaceutical Bulletin, 2004
Deuterium incorporation at the C-3 position of flavanones was achieved by treatment of flavanones and 2'-hydroxychalcones with D3PO4 and AcOD. We propose that the deuteration reaction mechanism for 2'-hydroxychalcones substrates is as follows. In the first step, 2'-hydroxychalcones cyclize to the corresponding flavanones by an intramolecular Michael ...
Hitoshi, Kagawa   +4 more
openaire   +3 more sources

Mechanisms of hesperetin in alleviating diabetic nephropathy: Network pharmacology, molecular docking, and experimental validation

open access: yesJournal of Diabetes Investigation, EarlyView.
Hesperetin increases cell viability and reduces cell apoptosis, ferroptosis, release of inflammatory cytokines, and oxidative stress of human kidney tubular cells via repressing IGF1R expression. ABSTRACT Background Diabetic nephropathy (DN) accounts for approximately 50% of chronic kidney disease cases.
Yiwen Guo   +4 more
wiley   +1 more source

Metabolo‐Transcriptomics Analyses Reveal Alfalfa Adaptation to Combined Saline‐Alkali and Low‐Temperature Stress in the Field

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT Alfalfa (Medicago sativa L.) is known as the ‘King of Forage’ because of its high protein content and excellent palatability. Alfalfa productivity is adversely affected in cold regions with saline‐alkali soils. However, the mechanisms underlying the response of alfalfa to combined saline‐alkali and low‐temperature stress under field conditions
Rui Guo   +8 more
wiley   +1 more source

Effect of thermal processing on the profile of bioactive compounds and antioxidant capacity of fermented orange juice [PDF]

open access: yes, 2016
Previously, we reported that alcoholic fermentation enhanced flavanones and carotenoids content of orange juice. The aim of this work was to evaluate the influence of pasteurization on the qualitative and quantitative profile of bioactive compounds and ...
AOAC   +14 more
core   +1 more source

An NADH-Dependent Reductase from Eubacterium ramulus Catalyzes the Stereospecific Heteroring Cleavage of Flavanones and Flavanonols

open access: yesApplied and Environmental Microbiology, 2019
Gut bacteria play a crucial role in the metabolism of dietary flavonoids, thereby contributing to their activation or inactivation after ingestion by the human host.
A. Braune, M. Gütschow, M. Blaut
semanticscholar   +1 more source

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