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The World of Algae Reveals a Broad Variety of Cryptochrome Properties and Functions

open access: yesFrontiers in Plant Science, 2021
Algae are photosynthetic eukaryotic (micro-)organisms, lacking roots, leaves, and other organs that are typical for land plants. They live in freshwater, marine, or terrestrial habitats.
Jan Petersen   +6 more
doaj   +1 more source

Enhanced small green fluorescent proteins as a multisensing platform for biosensor development

open access: yesFrontiers in Bioengineering and Biotechnology, 2022
Engineered light, oxygen, and voltage (LOV)-based proteins are able to fluoresce without oxygen requirement due to the autocatalytic incorporation of exogenous flavin as a chromophore thus allowing for live cell imaging under hypoxic and anaerobic ...
Guo-Teng Liang   +25 more
doaj   +1 more source

Disruptive innovation, the episteme and technology-enhanced learning in higher education

open access: yesPrometheus, 2021
This paper combines the theory of disruptive innovation with Foucault's concept of the episteme, in order to analyse the extent to which the integration of Foucauldian analysis clarifies understandings of disruptive innovation ...
Michael Flavin
doaj   +1 more source

Flavin oxidation in flavin‐dependent N‐monooxygenases [PDF]

open access: yesProtein Science, 2018
AbstractSiderophore A (SidA) from Aspergillus fumigatus is a flavin‐containing monooxygenase that hydroxylates ornithine (Orn) at the amino group of the side chain. Lysine (Lys) also binds to the active site of SidA; however, hydroxylation is not efficient and H2O2 is the main product.
Sobrado, Pablo   +3 more
openaire   +3 more sources

“I kind of feel resigned to the fact”:

open access: yesIrish Journal of Technology Enhanced Learning, 2023
Social media technologies are popular and pervasive. They also entail the submission of personal data which is sold on to third parties. Users trade their personal data in return for free access to social media services.
Michael Flavin
doaj   +3 more sources

An Abundant and Diverse New Family of Electron Bifurcating Enzymes With a Non-canonical Catalytic Mechanism

open access: yesFrontiers in Microbiology, 2022
Microorganisms utilize electron bifurcating enzymes in metabolic pathways to carry out thermodynamically unfavorable reactions. Bifurcating FeFe-hydrogenases (HydABC) reversibly oxidize NADH (E′∼−280 mV, under physiological conditions) and reduce protons
Gerrit J. Schut   +5 more
doaj   +1 more source

Flavofun: Exploration of fungal flavoproteomes

open access: yesFrontiers in Catalysis, 2022
Fungi produce a plethora of natural products exhibiting a fascinating diversity of chemical structures with an enormous potential for medical applications.
Bianca Kerschbaumer   +2 more
doaj   +1 more source

Surface-Enhanced Raman Spectroscopic Analysis of Flavoenzyme Cofactors: Guidance for Flavin-Related Bio- and Chemo- Sensors

open access: yesChemosensors, 2023
Flavin mononucleotides (FMNs) and flavin adenine nucleotide (FAD) play vital roles in the electron-transfer processes in diverse enzymatic reactions.
Yawen Liu   +5 more
doaj   +1 more source

Increased Yields of the Guanine Oxidative Damage Product Imidazolone Following Exposure to LED Light

open access: yesReactions, 2023
Among the bases of DNA, guanine is the most easily oxidized. Imidazolone (Iz) is a guanine oxidative damage, and we sought to generate Iz-containing oligomers. In this paper, we describe the methods and conditions to increase the yield of Iz by employing
Taishu Kawada   +2 more
doaj   +1 more source

Fixing flavins: hijacking a flavin transferase for equipping flavoproteins with a covalent flavin cofactor

open access: yesJournal of the American Chemical Society, 2023
Most flavin-dependent enzymes contain a dissociable flavin cofactor. We present a new approach for installing a covalent bond between a flavin cofactor and its hosting protein. By using a flavin transferase and carving a flavinylation motif in target proteins, we demonstrate that ‘dissociable’ flavoproteins can be turned into covalent flavoproteins ...
Yapei Tong   +5 more
openaire   +3 more sources

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