Results 51 to 60 of about 82,939 (224)

Disulfide Bond–Modified Proteomics Reveals the Effects of Riboflavin on Protein Folding Dynamics

Animal Research and One Health, EarlyView.
Riboflavin deficiency impairs oxidative protein folding, causing ER misfolded protein accumulation, CHOP activation, and apoptosis, revealing a role of riboflavin in proteostasis. ABSTRACT Riboflavin is a crucial micronutrient essential for maintaining cellular homeostasis, acting as an important precursor for flavoproteins that utilize flavin ...
Bo Zhang, Shuisheng Hou, Jing Tang
wiley   +1 more source

Photo-induced proton-coupled electron transfer and dissociation of isolated flavin adenine dinucleotide mono-anions

, 2017
Action spectroscopy experiments reveal the excited-state dynamics leading to dissociation of flavin adenine dinucleotide.
Mark H. Stockett, Stockett, Mark H.,
core   +1 more source

The in-silico study of the structural changes in the Arthrobacter globiformis choline oxidase induced by high temperature

Journal of Genetic Engineering and Biotechnology
Background: Choline oxidase, a flavoprotein, is an enzyme that catalyzes the reaction which converts choline into glycine betaine. Choline oxidase started its journey way back in 1933.
Sonia Kaushik, Rashmi Rameshwari, Shilpa S. Chapadgaonkar   +2 more
doaj   +1 more source

Flavin Electron Shuttles Dominate Extracellular Electron Transfer by Shewanella oneidensis

mBio, 2013
Shewanella oneidensis strain MR-1 is widely studied for its ability to respire a diverse array of soluble and insoluble electron acceptors. The ability to breathe insoluble substrates is defined as extracellular electron transfer and can occur via direct
Nicholas J. Kotloski, Jeffrey A. Gralnick   +1 more
doaj   +1 more source

The Activation of Cytochrome P450 2C9 Is Facilitated by the Coenzyme Forms of Vitamin B2

Molecules
The activity of cytochrome P450 enzymes decreases in older adults, which can lead to toxic effects from polypharmacy. Cytochromes P450 are the most significant enzymes involved in the metabolism of foreign compounds, including pharmaceutical substances ...
Polina I. Koroleva, Alexey V. Kuzikov, Andrei A. Gilep, Sergey V. Ivanov, Alexander I. Archakov, Victoria V. Shumyantseva   +5 more
doaj   +1 more source

Crystal Structure of the Apo-Form of NADPH-Dependent Thioredoxin Reductase from a Methane-Producing Archaeon

Antioxidants, 2018
The redox regulation of proteins via reversible dithiol/disulfide exchange reactions involves the thioredoxin system, which is composed of a reductant, a thioredoxin reductase (TR), and thioredoxin (Trx).
Rubén M. Buey, Ruth A. Schmitz, Bob B. Buchanan, Monica Balsera   +3 more
doaj   +1 more source

Intensifying Electron Utilization by Surface-Anchored Rh Complex for Enhanced Nicotinamide Cofactor Regeneration and Photoenzymatic CO2 Reduction

Research, 2021
Solar-driven photocatalytic regeneration of cofactors, including reduced nicotinamide adenine dinucleotide (NADH), reduced nicotinamide adenine dinucleotide phosphate (NADPH), and reduced flavin adenine dinucleotide (FADH2), could ensure the sustainable ...
Yuqing Cheng, Jiafu Shi, Yizhou Wu, Xueying Wang, Yiying Sun, Ziyi Cai, Yu Chen, Zhongyi Jiang   +7 more
doaj   +1 more source

Effects of catechins, resveratrol, silymarin components and some of their conjugates on xanthine oxidase‐catalyzed xanthine and 6‐mercaptopurine oxidation

Journal of the Science of Food and Agriculture, Volume 105, Issue 5, Page 2765-2776, 30 March 2025.
Abstract BACKGROUND Over the past two decades, the global incidence of gout has markedly increased, affecting people worldwide. Considering the side effects of xanthine oxidase (XO) inhibitor drugs (e.g. allopurinol and febuxostat) used in the treatment of hyperuricemia and gout, the potential application of phytochemicals has been widely studied.
Tímea Bencsik, Orsolya Balázs, Róbert G Vida, Balázs Z Zsidó, Csaba Hetényi, Kateřina Valentová, Miklós Poór   +6 more
wiley   +1 more source

Unusual folded conformation of nicotinamide adenine dinucleotide bound to flavin reductase P

, 2008
The 2.1 Å resolution crystal structure of flavin reductase P with the inhibitor nicotinamide adenine dinucleotide (NAD) bound in the active site has been determined.
Len Barbour (20810465), J.J. Tanner (21360332), C.L. Barnes (21359894), K.L. Krause (21360338), S.-C. Tu (21360335)   +4 more
core   +4 more sources

Production of Vitamin B2 (Riboflavin) by Microorganisms: An Overview

Frontiers in Bioengineering and Biotechnology, 2020
Riboflavin is a crucial micronutrient that is a precursor to coenzymes flavin mononucleotide and flavin adenine dinucleotide, and it is required for biochemical reactions in all living cells.
Liudmila A. Averianova, Larissa A. Balabanova, Larissa A. Balabanova, Oksana M. Son, Oksana M. Son, Anna B. Podvolotskaya, Anna B. Podvolotskaya, Liudmila A. Tekutyeva, Liudmila A. Tekutyeva   +8 more
doaj   +1 more source