Results 51 to 60 of about 20,065 (197)

Application of Negative Curvature Hollow-Core Fiber in an Optical Fiber Sensor Setup for Multiphoton Spectroscopy

open access: yesSensors, 2017
In this paper, an application of negative curvature hollow core fiber (NCHCF) in an all-fiber, multiphoton fluorescence sensor setup is presented. The dispersion parameter (D) of this fiber does not exceed the value of 5 ps/nm × km across the optical ...
Maciej Andrzej Popenda   +6 more
doaj   +1 more source

Label-Free Fluorescence Spectroscopy for Detecting Key Biomolecules in Brain Tissue from a Mouse Model of Alzheimer’s Disease

open access: yesScientific Reports, 2017
In this study, label-free fluorescence spectroscopy was used for the first time to determine spectral profiles of tryptophan, reduced nicotinamide adenine dinucleotide (NADH), and flavin denine dinucleotide (FAD) in fresh brain samples of a mouse model ...
Lingyan Shi   +5 more
doaj   +1 more source

Structures and mechanism of the monoamine oxidase family

open access: yesBiomolecular Concepts, 2011
Members of the monoamine oxidase family of flavoproteins catalyze the oxidation of primary and secondary amines, polyamines, amino acids, and methylated lysine side chains in proteins.
Gaweska Helena, Fitzpatrick Paul F.
doaj   +1 more source

FLIM as a Promising Tool for Cancer Diagnosis and Treatment Monitoring

open access: yesNano-Micro Letters, 2021
Fluorescence lifetime imaging microscopy (FLIM) has been rapidly developed over the past 30 years and widely applied in biomedical engineering. Recent progress in fluorophore-dyed probe design has widened the application prospects of fluorescence ...
Yuzhen Ouyang   +4 more
doaj   +1 more source

Disulfide Bond–Modified Proteomics Reveals the Effects of Riboflavin on Protein Folding Dynamics

open access: yesAnimal Research and One Health, EarlyView.
Riboflavin deficiency impairs oxidative protein folding, causing ER misfolded protein accumulation, CHOP activation, and apoptosis, revealing a role of riboflavin in proteostasis. ABSTRACT Riboflavin is a crucial micronutrient essential for maintaining cellular homeostasis, acting as an important precursor for flavoproteins that utilize flavin ...
Bo Zhang, Shuisheng Hou, Jing Tang
wiley   +1 more source

Cyclic-FMN Is a Detectable, Putative Intermediate of FAD Metabolism

open access: yesBiomolecules
Free flavin adenine dinucleotide (FAD) is metabolized to flavin mononucleotide (FMN) and adenine monophosphate (AMP) by hydrolases and to 4′,5′-cyclic phosphoriboflavin (cFMN) and AMP by the triose kinase FMN cyclase (TKFC).
Luxene Belfleur   +5 more
doaj   +1 more source

Detecting benign uterine tumors by autofluorescence lifetime imaging microscopy through adjacent healthy cervical tissues [PDF]

open access: yesJournal of Innovative Optical Health Sciences, 2019
The endogenous fluorophores such as reduced nicotinamide adenine dinucleotide (phosphate) (NAD(P)H) and flavin adenine dinucleotide (FAD) in cells and tissues can be imaged by fluorescence lifetime imaging microscopy (FLIM) to show the tissue morphology ...
Maojia Huang   +9 more
doaj   +1 more source

Pyruvate dehydrogenase autoantibodies in autoantibody‐negative patients with seizures are associated with reduced pyruvate dehydrogenase activity

open access: yesEpilepsia, EarlyView.
Abstract Objective We investigated the presence and potential functional relevance of antimitochondrial autoantibodies in patients suspicious for autoimmune encephalitis (AIE) associated with psychiatric symptoms and/or seizures, who were negative for known antineuronal autoantibodies.
Annika Breuer   +12 more
wiley   +1 more source

Not Cleaving the His-tag of Thal Results in More Tightly Packed and Better-Diffracting Crystals

open access: yesCrystals, 2020
Flavin-dependent halogenases chlorinate or brominate their substrates in an environmentally friendly manner, only requiring the cofactor reduced flavin adenine dinucleotide (FADH2), oxygen, and halide salts.
Ann-Christin Moritzer   +2 more
doaj   +1 more source

Characterization of Two VAO-Type Flavoprotein Oxidases from Myceliophthora thermophila

open access: yesMolecules, 2018
The VAO flavoprotein family consists mostly of oxidoreductases harboring a covalently linked flavin cofactor. The linkage can be either monocovalent at position 8 with a histidine or tyrosine or bicovalent at position 8 with a histidine and at position 6
Alessandro R. Ferrari   +5 more
doaj   +1 more source

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