Results 121 to 130 of about 111,183 (286)
, 2021 Flavoproteins are of key importance to all life on earth for both primary and secondary metabolism. Most flavin-dependent enzymes utilize flavin mononucleotide (FMN) or flavin adenine dinucleotide (FAD) as redox cofactor for single-electron and hydride transfer as well as oxidation and oxygenation chemistry at the C4a-locus.
Drenth, Jeroen, Fraaije, Marco W.
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iMeta, EarlyView.The pervasiveness of microplastic pollution poses a growing health risk, yet its long‐term metabolic consequences remain poorly defined. Here, we exposed mice to polyethylene terephthalate nanoparticle (NP) and combined histopathology, biochemistry, metabolomics, and metagenomics to resolve their interactions.
Yi Zhang +11 more
wiley +1 more source
Journal of the Science of Food and Agriculture, Volume 105, Issue 5, Page 2765-2776, 30 March 2025.Abstract BACKGROUND Over the past two decades, the global incidence of gout has markedly increased, affecting people worldwide. Considering the side effects of xanthine oxidase (XO) inhibitor drugs (e.g. allopurinol and febuxostat) used in the treatment of hyperuricemia and gout, the potential application of phytochemicals has been widely studied.
Tímea Bencsik +6 more
wiley +1 more source
JEADV Clinical Practice, EarlyView.ABSTRACT Background Porokeratoses represent a group of keratinization disorders characterized histopathologically by the presence of a cornoid lamella. The recognition of porokeratosis as a genodermatosis, along with its association with increased risk of skin cancer, underscores the importance of accurate and timely diagnosis.
Rahime Inci +5 more
wiley +1 more source
Energetics of the Citric Acid Cycle in the Deep Biosphere
Geophysical Monograph Series, Page 303-327., 2020 This book is Open Access. A digital copy can be downloaded for free from Wiley Online Library.
Explores the behavior of carbon in minerals, melts, and fluids under extreme conditions
Carbon trapped in diamonds and carbonate-bearing rocks in subduction zones are examples of the continuing exchange of substantial carbon ...
Peter A. Canovas III, Everett L. Shock
wiley +1 more source
Structure and Mechanism of PhdC, a Prenylated‐Flavin Maturase
Proteins: Structure, Function, and Bioinformatics, EarlyView.ABSTRACT Prenylated flavin mononucleotide (prFMN) is a modified flavin cofactor required by the UbiD family of (de)carboxylase enzymes. While the reduced prFMNH2 form is produced by the flavin prenyltransferase UbiX, the corresponding two‐electron oxidized prFMNiminium form is required to support UbiD catalysis. Thus, oxidative maturation of prFMNH2 is
Dominic R. Whittall +4 more
wiley +1 more source
Versatile roles of protein flavinylation in bacterial extracyotosolic electron transfer
mSystemsBacteria perform diverse redox chemistries in the periplasm, cell wall, and extracellular space. Electron transfer for these extracytosolic activities is frequently mediated by proteins with covalently bound flavins, which are attached through post ...
Shuo Huang +3 more
doaj +1 more source
Sustainable Development, EarlyView.ABSTRACT The promotion of clean energy is critical to achieving sustainable development. This study investigates the factors that affect the exports, trade potential, and revealed comparative advantage (RCA) of clean energy products (CEPs) in the emerging Asian economies (EAEs).
Arvind Goswami +2 more
wiley +1 more source
NQO1‐Responsive Prodrug for in Cellulo Release of Cytochalasin B as Cancer Cell‐Targeted Migrastatic
Small, EarlyView.The design, synthesis, biochemical, and cell biological evaluation of the NQO1‐targeted prodrug BQTML‐CB is reported. BQTML‐CB selectively releases cytochalasin B upon activation by the quinone‐oxidoreductase NQO1 associated with invasiveness of cancer cells, representing a novel approach to improve cancer selectivity and reduce immunosuppressive ...
Mervic D. Kagho +10 more
wiley +1 more source
Small, EarlyView.We present a high‐performance enzymatic biofuel cell based on a micro‐corrugated hydrogel electrode engineered via capillary force and ligand exchange‐induced assembly of tetra(octylammonium) (TOA)‐stabilized Au nanoparticles (Au NPs). The resulting metallic TOA‐Au NPs hydrogel structure enables seamless electron transfer and stable enzyme ...
Eunju Choi +10 more
wiley +1 more source