FLAVi: An Enhanced Annotator for Viral Genomes of Flaviviridae [PDF]
Viruses, 2020 Responding to the ongoing and severe public health threat of viruses of the family Flaviviridae, including dengue, hepatitis C, West Nile, yellow fever, and Zika, demands a greater understanding of how these viruses emerge and spread. Updated phylogenies
Adriano de Bernadi Schneider +3 more
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Proteochemometric Method for pIC50 Prediction of Flaviviridae [PDF]
BioMed Research International, 2022 Viruses remain an area of concern despite constant development of antiviral drugs and therapies. One of the contributors among others is the flaviviridae family of viruses.
Divye Singh +3 more
semanticscholar +4 more sources
ICTV Virus Taxonomy Profile: Flaviviridae
Journal of General Virology, 2017 The Flaviviridae is a family of small enveloped viruses with RNA genomes of 9000–13 000 bases. Most infect mammals and birds. Many flaviviruses are host-specific and pathogenic, such as hepatitis C virus in the genus Hepacivirus.
Peter Simmonds +10 more
semanticscholar +4 more sources
Flaviviridae Nonstructural Proteins: The Role in Molecular Mechanisms of Triggering Inflammation
Viruses, 2022 Members of the Flaviviridae family are posing a significant threat to human health worldwide. Many flaviviruses are capable of inducing severe inflammation in humans.
Anastasia Latanova +2 more
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Dual-Role Ubiquitination Regulation Shuttling the Entire Life Cycle of the Flaviviridae
Frontiers in Microbiology, 2022 Ubiquitination is a reversible protein post-translational modification that regulates various pivotal physiological and pathological processes in all eukaryotes.
Dongjie Cai +12 more
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Molecular Events Occurring in Lipophagy and Its Regulation in Flaviviridae Infection
Frontiers in Microbiology, 2021 Diseases caused by Flaviviridae have a wide global and economic impact due to high morbidity and mortality. Flaviviridae infection usually leads to severe, acute or chronic diseases, such as liver injury and liver cancer resulting from hepatitis C virus (
Keke Wu +19 more
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A New Subclass of Exoribonuclease-Resistant RNA Found in Multiple Genera of
mBio, 2020 Viruses have developed innovative strategies to exploit the cellular machinery and overcome the antiviral defenses of the host, often using specifically structured RNA elements.
Matthew J. Szucs +4 more
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Proposed revision to the taxonomy of the genus Pestivirus, family Flaviviridae [PDF]
Journal of General Virology, 2017 We propose the creation of seven new species in the genus Pestivirus (family Flaviviridae) in addition to the four existing species, and naming species in a host-independent manner using the format Pestivirus X. Only the virus species names would change;
Donald B. Smith +10 more
semanticscholar +7 more sources
In Vivo Dynamics of Reporter Flaviviridae Viruses [PDF]
Journal of Virology, 2019 In vivo applications of reporter viruses are necessary to understand viral pathogenesis and provide a robust platform for antiviral development. In developing such applications, determination of an ideal locus to accommodate foreign genes is important ...
Tomokazu Tamura +13 more
semanticscholar +6 more sources
Innate Immune Evasion Mediated by Flaviviridae Non-Structural Proteins
Viruses, 2017 Flaviviridae-caused diseases are a critical, emerging public health problem worldwide. Flaviviridae infections usually cause severe, acute or chronic diseases, such as liver damage and liver cancer resulting from a hepatitis C virus (HCV) infection and ...
Shun Chen +3 more
doaj +2 more sources