Results 11 to 20 of about 40,099 (291)
Flaviviridae Nonstructural Proteins: The Role in Molecular Mechanisms of Triggering Inflammation
Viruses, 2022 Members of the Flaviviridae family are posing a significant threat to human health worldwide. Many flaviviruses are capable of inducing severe inflammation in humans.
Anastasia Latanova +2 more
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Mapping glycoprotein structure reveals Flaviviridae evolutionary history [PDF]
NatureViral glycoproteins drive membrane fusion in enveloped viruses and determine host range, tissue tropism and pathogenesis1. Despite their importance, there is a fragmentary understanding of glycoproteins within the Flaviviridae2, a large virus family that
Jonathon C O Mifsud +2 more
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Molecular Events Occurring in Lipophagy and Its Regulation in Flaviviridae Infection
Frontiers in Microbiology, 2021 Diseases caused by Flaviviridae have a wide global and economic impact due to high morbidity and mortality. Flaviviridae infection usually leads to severe, acute or chronic diseases, such as liver injury and liver cancer resulting from hepatitis C virus (
Keke Wu +19 more
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Proteochemometric Method for pIC50 Prediction of Flaviviridae
BioMed Research International, 2022 Viruses remain an area of concern despite constant development of antiviral drugs and therapies. One of the contributors is the Flaviviridae family of viruses causing diseases that need attention. Among other anitviral methods, antiviral peptides are being studied as viable candidates.
Divye Singh +3 more
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A New Subclass of Exoribonuclease-Resistant RNA Found in Multiple Genera of
mBio, 2020 Viruses have developed innovative strategies to exploit the cellular machinery and overcome the antiviral defenses of the host, often using specifically structured RNA elements.
Matthew J. Szucs +4 more
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European College of Equine Internal Medicine consensus statement on equine flaviviridae infections in Europe [PDF]
Journal of Veterinary Internal Medicine, 2022 Horses and other equids can be infected with several viruses of the family Flaviviridae, belonging to the genus Flavivirus and Hepacivirus. This consensus statement focuses on viruses with known occurrence in Europe, with the objective to summarize the ...
Jessika‐M. V. Cavalleri +6 more
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Viruses, 2020 The Flaviviridae virus family is classified into four different genera, including flavivirus, hepacivirus, pegivirus, and pestivirus, which cause significant morbidity and mortality in humans and other mammals, including ruminants and pigs.
Nabeel Alzahrani +3 more
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FLAVi: An Enhanced Annotator for Viral Genomes of Flaviviridae
Viruses, 2020 Responding to the ongoing and severe public health threat of viruses of the family Flaviviridae, including dengue, hepatitis C, West Nile, yellow fever, and Zika, demands a greater understanding of how these viruses emerge and spread. Updated phylogenies
Adriano de Bernadi Schneider +3 more
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ICTV Virus Taxonomy Profile: Flaviviridae
Journal of General Virology, 2017 The Flaviviridae is a family of small enveloped viruses with RNA genomes of 9000–13 000 bases. Most infect mammals and birds. Many flaviviruses are host-specific and pathogenic, such as hepatitis C virus in the genus Hepacivirus. The majority of known members in the genus Flavivirus are arthropod borne, and many are important human and veterinary ...
Simmonds, P +11 more
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Flaviviridae Viruses and Oxidative Stress: Implications for Viral Pathogenesis [PDF]
Oxidative Medicine and Cellular Longevity, 2019 Oxidative stress is induced once the balance of generation and neutralization of reactive oxygen species (ROS) is broken in the cell, and it plays crucial roles in a variety of natural and diseased processes.
Zhenzhen Zhang, Rong Liang, Yi‐Ping Li
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