Results 21 to 30 of about 20,416 (183)

A systematic bioinformatics approach for large-scale identification and characterization of host-pathogen shared sequences

open access: yesBMC Genomics, 2021
Background Biology has entered the era of big data with the advent of high-throughput omics technologies. Biological databases provide public access to petabytes of data and information facilitating knowledge discovery.
Stephen Among James   +3 more
doaj   +1 more source

New Insights into the Role and Therapeutic Potential of Heat Shock Protein 70 in Bovine Viral Diarrhea Virus Infection

open access: yesMicroorganisms, 2023
Bovine viral diarrhea virus (BVDV), a positive-strand RNA virus of the genus Pestivirus in the Flaviviridae family, is the causative agent of bovine viral diarrhea–mucosal disease (BVD-MD).
Nannan Chen   +6 more
doaj   +1 more source

Ultrastructural aspects of virus replication in one fatal case and several other isolates from a dengue type 2 outbreak in Rio de Janeiro

open access: yesMemorias do Instituto Oswaldo Cruz, 1994
Dengue virus replication in mosquito cell cultures was observed by electron microscopy in one fatal and 40 classical isolates from a dengue type 2 outbreak in Rio de Janeiro and compared with the prototype New Guinea C strain.
Ortrud Monika Barth   +3 more
doaj   +1 more source

In vitro and in silico Models to Study Mosquito-Borne Flavivirus Neuropathogenesis, Prevention, and Treatment

open access: yesFrontiers in Cellular and Infection Microbiology, 2019
Mosquito-borne flaviviruses can cause disease in the nervous system, resulting in a significant burden of morbidity and mortality. Disease models are necessary to understand neuropathogenesis and identify potential therapeutics and vaccines.
Megan Chesnut   +10 more
doaj   +1 more source

Cross-Protection of Dengue Virus Infection against Congenital Zika Syndrome, Northeastern Brazil

open access: yesEmerging Infectious Diseases, 2019
The Zika virus outbreak in Latin America resulted in congenital malformations, called congenital Zika syndrome (CZS). For unknown reasons, CZS incidence was highest in northeastern Brazil; one potential explanation is that dengue virus (DENV)–mediated ...
Celia Pedroso   +10 more
doaj   +1 more source

A New Subclass of Exoribonuclease-Resistant RNA Found in Multiple Genera of Flaviviridae

open access: yesmBio, 2020
Viruses have developed innovative strategies to exploit the cellular machinery and overcome the antiviral defenses of the host, often using specifically structured RNA elements.
Matthew J. Szucs   +4 more
doaj   +1 more source

The envelope protein of Zika virus interacts with apolipoprotein E early in the infectious cycle and this interaction is conserved on the secreted viral particles

open access: yesVirology Journal, 2022
Background Zika virus (ZIKV), a member of the Flaviviridae family, has caused massive outbreaks of infection in tropical areas over the last decade and has now begun spreading to temperate countries.
Yannick Tréguier   +7 more
doaj   +1 more source

West Nile Virus Infection

open access: yesPathogens, 2023
West Nile virus (WNV) is a mosquito-borne pathogen that belongs to the Flavivirus genus (family Flaviviridae) [...]
Francisco Llorente
doaj   +1 more source

Innate Immune Evasion Mediated by Flaviviridae Non-Structural Proteins

open access: yesViruses, 2017
Flaviviridae-caused diseases are a critical, emerging public health problem worldwide. Flaviviridae infections usually cause severe, acute or chronic diseases, such as liver damage and liver cancer resulting from a hepatitis C virus (HCV) infection and ...
Shun Chen   +3 more
doaj   +1 more source

FLAVi: An Enhanced Annotator for Viral Genomes of Flaviviridae

open access: yesViruses, 2020
Responding to the ongoing and severe public health threat of viruses of the family Flaviviridae, including dengue, hepatitis C, West Nile, yellow fever, and Zika, demands a greater understanding of how these viruses emerge and spread. Updated phylogenies
Adriano de Bernadi Schneider   +3 more
doaj   +1 more source

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