Results 31 to 40 of about 20,519 (176)

FLAVi: An Enhanced Annotator for Viral Genomes of Flaviviridae

Viruses, 2020
Responding to the ongoing and severe public health threat of viruses of the family Flaviviridae, including dengue, hepatitis C, West Nile, yellow fever, and Zika, demands a greater understanding of how these viruses emerge and spread. Updated phylogenies
Adriano de Bernadi Schneider, Denis Jacob Machado, Sayal Guirales, Daniel A. Janies   +3 more
doaj   +1 more source

Omsk Hemorrhagic Fever Virus: A Comprehensive Review from Epidemiology to Diagnosis and Treatment

Microorganisms
Omsk hemorrhagic fever virus (OHFV) is the etiological agent of a poorly studied acute viral disease, causing several epidemic waves observed in the western Siberia regions of Omsk, Kurgan, Novosibirsk, and Tyumen.
Erica Diani, Riccardo Cecchetto, Emil Tonon, Marco Mantoan, Virginia Lotti, Anna Lagni, Asia Palmisano, Pier Paolo Piccaluga, Davide Gibellini   +8 more
doaj   +1 more source

The core protein of classical Swine Fever virus is dispensable for virus propagation in vitro. [PDF]

PLoS Pathogens, 2012
Core protein of Flaviviridae is regarded as essential factor for nucleocapsid formation. Yet, core protein is not encoded by all isolates (GBV- A and GBV- C).
Christiane Riedel, Benjamin Lamp, Manuela Heimann, Matthias König, Sandra Blome, Volker Moennig, Christian Schüttler, Heinz-Jürgen Thiel, Tillmann Rümenapf   +8 more
doaj   +1 more source

Test systems for the laboratory detection and differentiation of Powassan virus from tick-borne encephalitis virus (Flaviviridae: Orthoflavivirus) using RT-PCR and RT-qPCR

Вопросы вирусологии
Introduction. Powassan virus (POWV) is a tick-borne orthoflavivirus capable of causing neurological diseases. In the Russian Far East, the area affected by POWV overlaps with that of another neurotropic orthoflavivirus, tick-borne encephalitis virus ...
Maria P. Fedina, Roman I. Ivannikov, Galina G. Karganova, Alexander G. Litov   +3 more
doaj   +1 more source

Atypical Porcine Pestivirus Molecular Evolution within a Persistently Infected Swine Farm

Proceedings, 2020
Atypical porcine pestivirus (APPV) is a single stranded RNA virus from the family Flaviviridae. [...]
Alba Folgueiras-González, Robin van den Braak, Bartjan Simmelink, Martin Deijs, Ad de Groof, Lia van der Hoek   +5 more
doaj   +1 more source

CRISPR–Cas system to discover host-virus interactions in Flaviviridae

Virology Journal, 2023
The Flaviviridae virus family members cause severe human diseases and are responsible for considerable mortality and morbidity worldwide. Therefore, researchers have conducted genetic screens to enhance insight into viral dependency and develop potential
Zahra Ramezannia, Ali Shamekh, Hossein Bannazadeh Baghi   +2 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Human Pegivirus Encephalitis With Brain Detection and Response to Sofosbuvir Ledipasvir

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Human pegivirus (HPgV‐1) has been associated with severe encephalomyelitis in immunocompromised patients. Its neurological spectrum remains poorly defined. We report a slowly progressive encephalitis in a person living with well‐controlled HIV, characterized by white matter abnormalities and inflammatory cerebrospinal fluid (CSF). HPgV RNA was
Antoine Moulignier, Françoise Heran, Francis Lallemand, Pierre Bourdillon   +3 more
wiley   +1 more source

Vaccine development for mosquito-borne viral diseases

Frontiers in Immunology, 2023
Mosquito-borne viral diseases are a group of viral illnesses that are predominantly transmitted by mosquitoes, including viruses from the Togaviridae and Flaviviridae families.
Zhiwei Huang, Yuxuan Zhang, Hongyu Li, Jiajie Zhu, Wanchen Song, Keda Chen, Yanjun Zhang, Yongliang Lou   +7 more
doaj   +1 more source

UCHL3 Regulates Subgenomic Flaviviral RNA Condensates to Promote Virus Propagation

Advanced Science, EarlyView.
ABSTRACT Flavivirus subgenomic RNAs (sfRNAs) antagonise antiviral defences, yet how sfRNAs are organized and maintained in cells remains poorly understood. Here we identify ubiquitin C‐terminal hydrolase L3 (UCHL3) as a post‐translational regulator of flavivirus sfRNA stability and function.
Oscar Trejo‐Cerro, Anna Beekmayer‐Dhillon, Qi Wen Teo, Lewis Siu, Ming Yuan Li, Kate J. Heesom, Adán Pinto‐Fernández, Sumana Sanyal   +7 more
wiley   +1 more source