Identification of novel neutralizing determinants for protection against HCV
Identification of novel neutralizing determinants for protection against hepatitis C virus. Abstract Background and Aims HCV evasion of neutralizing antibodies (nAb) results in viral persistence and poses challenges to the development of an urgently needed vaccine.
Garazi P. Alzua +12 more
wiley +1 more source
West Nile Virus: Seroprevalence and Epidemiological Study in Blood Donors in North Central Anatolia Amid Global Threats. [PDF]
ABSTRACT West Nile virus (WNV) is a pathogen belonging to the family Flaviviridae and the genus Flavivirus. This study examined WNV IgG antibodies in healthy blood donors at Hitit University Blood Centre in Corum, Türkiye, during 2019–2020 using ELISA, thereby providing seroepidemiological data on WNV in northern central Anatolia.
Gureser AS +3 more
europepmc +2 more sources
Flaviviridae Nonstructural Proteins: The Role in Molecular Mechanisms of Triggering Inflammation
Members of the Flaviviridae family are posing a significant threat to human health worldwide. Many flaviviruses are capable of inducing severe inflammation in humans.
Anastasia Latanova +2 more
doaj +1 more source
Virus-host coevolution: common patterns of nucleotide motif usage in Flaviviridae and their hosts. [PDF]
Virus-host biological interaction is a continuous coevolutionary process involving both host immune system and viral escape mechanisms. Flaviviridae family is composed of fast evolving RNA viruses that infects vertebrate (mammals and birds) and/or ...
Francisco P Lobo +7 more
doaj +1 more source
The family Flaviviridae comprises the genus Flavivirus, which contains 65 related species and two possible members. They are small, enveloped RNA viruses (diameter 45 nm) with peplomers comprising a single glycoprotein E. Other structural proteins are designated C (core) and M (membrane-like).
Horzinek, M.C. +9 more
openaire +3 more sources
Deep Sequencing Analysis of RNAs from Citrus Plants Grown in a Citrus Sudden Death-Affected Area Reveals Diverse Known and Putative Novel Viruses. [PDF]
Citrus sudden death (CSD) has caused the death of approximately four million orange trees in a very important citrus region in Brazil. Although its etiology is still not completely clear, symptoms and distribution of affected plants indicate a viral ...
Coletta-Filho, Helvecio D +7 more
core +3 more sources
Powassan Meningoencephalitis, New York, New York, USA
Disease caused by Powassan virus (POWV), a tick-borne flavivirus, ranges from asymptomatic to severe neurologic compromise and death. Two cases of POWV meningoencephalitis in New York, USA, highlight diagnostic techniques, neurologic outcomes, and the ...
Simon Sung +7 more
doaj +1 more source
Differential effects of lipid biosynthesis inhibitors on Zika and Semliki Forest viruses [PDF]
The recent outbreak of infection with Zika virus (ZIKV; Flaviviridae) has attracted attention to this previously neglected mosquito-borne pathogen and the need for efficient therapies.
Donald, Claire L. +4 more
core +1 more source
Phylogeny of Culex theileri virus flavivirus in Spain, Myanmar, Portugal and Turkey
Objective: To study the genetic diversity of Culex theileri flavivirus and the spread of this virus among Spain, Portugal and Turkey. Methods: A database consisting of 55 sequences of the NS5/3’UTR region of Culex theileri flavivirus group downloaded ...
Eleonora Cella +6 more
doaj +1 more source
Background Biology has entered the era of big data with the advent of high-throughput omics technologies. Biological databases provide public access to petabytes of data and information facilitating knowledge discovery.
Stephen Among James +3 more
doaj +1 more source

