Results 21 to 30 of about 6,094 (193)
Dual-Role Ubiquitination Regulation Shuttling the Entire Life Cycle of the Flaviviridae
Frontiers in Microbiology, 2022 Ubiquitination is a reversible protein post-translational modification that regulates various pivotal physiological and pathological processes in all eukaryotes.
Dongjie Cai +12 more
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Molecular Events Occurring in Lipophagy and Its Regulation in Flaviviridae Infection
Frontiers in Microbiology, 2021 Diseases caused by Flaviviridae have a wide global and economic impact due to high morbidity and mortality. Flaviviridae infection usually leads to severe, acute or chronic diseases, such as liver injury and liver cancer resulting from hepatitis C virus (
Keke Wu +19 more
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CRISPR–Cas system to discover host-virus interactions in Flaviviridae [PDF]
Virology Journal, 2023 The Flaviviridae virus family members cause severe human diseases and are responsible for considerable mortality and morbidity worldwide. Therefore, researchers have conducted genetic screens to enhance insight into viral dependency and develop potential
Zahra Ramezannia +2 more
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Viruses, 2021 Pestiviruses are plus-stranded RNA viruses belonging to the family Flaviviridae. They comprise several important pathogens like classical swine fever virus and bovine viral diarrhea virus that induce economically important animal diseases.
Alexander Postel +2 more
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A New Subclass of Exoribonuclease-Resistant RNA Found in Multiple Genera of
mBio, 2020 Viruses have developed innovative strategies to exploit the cellular machinery and overcome the antiviral defenses of the host, often using specifically structured RNA elements.
Matthew J. Szucs +4 more
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Implementation of IFPTML Computational Models in Drug Discovery Against Flaviviridae Family [PDF]
Journal of Chemical Information and ModelingThe Flaviviridae family consists of single-stranded positive-sense RNA viruses, which contains the genera Flavivirus, Hepacivirus, Pegivirus, and Pestivirus.
Yendrek Velásquez-López +3 more
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Virus-Host Coevolution: Common Patterns of Nucleotide Motif Usage in Flaviviridae and Their Hosts [PDF]
PLoS ONE, 2009 Virus-host biological interaction is a continuous coevolutionary process involving both host immune system and viral escape mechanisms. Flaviviridae family is composed of fast evolving RNA viruses that infects vertebrate (mammals and birds) and/or ...
Francisco P Lobo
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Genetic dissection of Flaviviridae host factors through genome-scale CRISPR screens
Nature, 2016 The Flaviviridae are a family of viruses that cause severe human diseases. For example, dengue virus (DENV) is a rapidly emerging pathogen causing an estimated 100 million symptomatic infections annually worldwide. No approved antivirals are available to
Andreas S Puschnik +2 more
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Viruses, 2020 The Flaviviridae virus family is classified into four different genera, including flavivirus, hepacivirus, pegivirus, and pestivirus, which cause significant morbidity and mortality in humans and other mammals, including ruminants and pigs.
Nabeel Alzahrani +3 more
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Perspectives for the Treatment of Infections withFlaviviridae [PDF]
Clinical Microbiology Reviews, 2000 SUMMARYThe family Flaviviridae contains three genera: Hepacivirus, Flavivirus, and Pestivirus. Worldwide, more than 170 million people are chronically infected with Hepatitis C virus and are at risk of developing cirrhosis and/or liver cancer. In addition, infections with arthropod-borne flaviviruses (such as dengue fever, Japanese encephalitis, tick ...
Pieter Leyssen +2 more
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