Mapping glycoprotein structure reveals defining events in the evolution of theFlaviviridae
bioRxivViral glycoproteins drive membrane fusion in enveloped viruses and determine host range, tissue tropism and pathogenesis. Despite their importance, there is a fragmentary understanding of glycoproteins within the Flaviviridae; for many species the ...
Mifsud JC +6 more
europepmc +2 more sources
Importin-7-dependent nuclear translocation of the Flavivirus core protein is required for infectious virus production. [PDF]
PLoS PathogensFlaviviridae is a family of positive-stranded RNA viruses, including human pathogens, such as Japanese encephalitis virus (JEV), dengue virus (DENV), Zika virus (ZIKV), and West Nile virus (WNV).
Yumi Itoh +12 more
doaj +2 more sources
Proposed revision to the taxonomy of the genus Pestivirus, family Flaviviridae [PDF]
Journal of General Virology, 2017 We propose the creation of seven new species in the genus Pestivirus (family Flaviviridae) in addition to the four existing species, and naming species in a host-independent manner using the format Pestivirus X. Only the virus species names would change;
Donald B. Smith +10 more
semanticscholar +7 more sources
A Review on The Pathogenesis of Cardiovascular Disease of Flaviviridea Viruses Infection [PDF]
VirusesMembers of the Flaviviridae family, encompassing the Flavivirus and Hepacivirus genera, are implicated in a spectrum of severe human pathologies. These diseases span a diverse spectrum, including hepatitis, vascular shock syndrome, encephalitis, acute ...
Tie-Hua Yang +7 more
doaj +2 more sources
Virus-Like Particle Systems for Vaccine Development against Viruses in the Flaviviridae Family
Vaccines, 2019 Viruses in the Flaviviridae family are important human and animal pathogens that impose serious threats to global public health. This family of viruses includes emerging and re-emerging viruses, most of which are transmitted by infected mosquito or tick ...
Shu Hui Wong +5 more
doaj +2 more sources
Proteochemometric Method for pIC50 Prediction of Flaviviridae [PDF]
BioMed Research International, 2022 Viruses remain an area of concern despite constant development of antiviral drugs and therapies. One of the contributors is the Flaviviridae family of viruses causing diseases that need attention. Among other anitviral methods, antiviral peptides are being studied as viable candidates.
Divye Singh +3 more
openalex +3 more sources
Frontiers in Microbiology, 2017 Lipid droplets (LDs) are endoplasmic reticulum (ER)-related dynamic organelles that store and regulate fatty acids and neutral lipids. They play a central role in cellular energy storage, lipid metabolism and cellular homeostasis.
Jingshu Zhang +3 more
doaj +2 more sources
Virus-encoded proteinases of the Flaviviridae.
Journal of General Virology, 1998 Martin D. Ryan +2 more
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hsa-miR-548d-3p: a potential microRNA to target nucleocapsid and/or capsid genes in multiple members of the Flaviviridae family. [PDF]
Front BioinformCayatineto HW, Hakim ST.
europepmc +2 more sources
The first study on analysis of the codon usage bias and evolutionary analysis of the glycoprotein envelope E2 gene of seven Pestiviruses [PDF]
Veterinary World, 2022 Background and Aim: Pestivirus, a genus of the Flaviviridae family, comprises viruses that affect bovines, sheep, and pigs. Symptoms, including hemorrhagic syndromes, abortion, respiratory complications, and deadly mucosal diseases, are produced in ...
Mohammad Shueb +12 more
doaj +1 more source