Results 31 to 40 of about 36,247 (268)

Perspectives for the Treatment of Infections withFlaviviridae [PDF]

Clinical Microbiology Reviews, 2000
SUMMARYThe family Flaviviridae contains three genera: Hepacivirus, Flavivirus, and Pestivirus. Worldwide, more than 170 million people are chronically infected with Hepatitis C virus and are at risk of developing cirrhosis and/or liver cancer. In addition, infections with arthropod-borne flaviviruses (such as dengue fever, Japanese encephalitis, tick ...
Pieter Leyssen, Erik De Clercq, Johan Neyts   +2 more
openalex   +5 more sources

Trends in the Seroprevalence of Dengue in a Tertiary Care Hospital of North Karnataka, India [PDF]

National Journal of Laboratory Medicine, 2022
Introduction: Dengue virus of the Flaviviridae family is the causative agent of dengue fever. The Aedes aegypti mosquito is the main vector for its transmission.
Aisha Parande, Rupali Shinde, Mahantesh Parande, Rubeena Ishrat Mulla, Uma Chikkaraddi   +4 more
doaj   +1 more source

Implementation of IFPTML Computational Models in Drug Discovery Against Flaviviridae Family. [PDF]

J Chem Inf Model
Velásquez-López Y, Ruiz-Escudero A, Arrasate S, González-Díaz H.   +3 more
europepmc   +3 more sources

Continuous surveillance of potentially zoonotic avian pathogens detects contemporaneous occurrence of highly pathogenic avian influenza viruses (HPAIV H5) and flaviviruses (USUV, WNV) in several wild and captive birds

Emerging Microbes and Infections, 2023
Three avian viral pathogens circulate in Germany with particular importance for animal disease surveillance due to their zoonotic potential, their impact on wild bird populations and/or poultry farms: Highly pathogenic (HP) avian influenza virus (AIV) of
Anne Günther, Anne Pohlmann, Anja Globig, Ute Ziegler, Sten Calvelage, Markus Keller, Dominik Fischer, Christoph Staubach, Martin H. Groschup, Timm Harder, Martin Beer   +10 more
doaj   +1 more source

Transcriptome mining extends the host range of the Flaviviridae to non-bilaterians

bioRxiv, 2022
The Flaviviridae are a family of positive-sense RNA viruses that include well-documented agents of human disease. Despite their importance and ubiquity, the time-scale of flaviviral evolution is uncertain.
Jonathon C. O. Mifsud, Vincenzo A. Costa, M. Petrone, E. Marzinelli, E. Holmes, Erin Harvey   +5 more
semanticscholar   +1 more source

Identification of novel neutralizing determinants for protection against HCV

Hepatology, EarlyView., 2022
Identification of novel neutralizing determinants for protection against hepatitis C virus. Abstract Background and Aims HCV evasion of neutralizing antibodies (nAb) results in viral persistence and poses challenges to the development of an urgently needed vaccine.
Garazi P. Alzua, Anne F. Pihl, Anna Offersgaard, Rodrigo Velázquez‐Moctezuma, Carlos R. Duarte Hernandez, Elias H. Augestad, Ulrik Fahnøe, Christian K. Mathiesen, Henrik Krarup, Mansun Law, Jannick Prentoe, Jens Bukh, Judith M. Gottwein   +12 more
wiley   +1 more source

Integrated analysis of protein sequence and structure redefines viral diversity and the taxonomy of theFlaviviridae

Simmonds P, Butković A, Grove J, Mayne R, Mifsud JCO, Beer M, Bukh J, Drexler JF, Kapoor A, Lohmann V, Smith DB, Stapleton JT, Vasilakis N, Kuhn JH.   +13 more
europepmc   +2 more sources

Insect‐specific viruses used in biocontrol of mosquito‐borne diseases

Interdisciplinary Medicine, Volume 1, Issue 1, January 2023., 2023
Insect‐specific RNA viruses (ISRVs) are involved in a wide range of families including Flaviviridae, Bunyaviridae, Negeviruses, Togaviridae, Reoviridae, Mesoniviridae, and Rhabdoviridae, which cannot infect vertebrates, including humans. However, ISRVs can infect and replicate in mosquitoes, interfering with the replication of mosquito‐borne viruses ...
Jiating Chen, Shengqun Deng, Hongjuan Peng   +2 more
wiley   +1 more source

Structural Motifs and Spatial Structures of Helicase (NS3) and RNA-dependent RNA-polymerase (NS5) of a Flavi-like Kindia tick virus (unclassified Flaviviridae)

Вопросы вирусологии, 2023
Introduction. Kindia tick virus (KITV) is a novel segmented unclassified flavi-like virus of the Flaviviridae family. This virus is associated with ixodes ticks and is potentially pathogenic to humans.
A. A. Gladysheva, A. V. Gladysheva, V. A. Ternovoi, V. B. Loktev   +3 more
doaj   +1 more source

Non‐cytopathic bovine viral diarrhoea virus 2 induces autophagy to enhance its replication

Veterinary Medicine and Science, Volume 9, Issue 1, Page 405-416, January 2023., 2023
Ncp BVDV2 infection induced autophagy in MDBK cells via anti‐apoptosis and PKR suppression. Autophagy may play a role in establishing persistent infection caused by ncp BVDV. Abstract Background Bovine viral diarrhoea virus (BVDV) is an important viral pathogen that has an economic impact on the livestock industry worldwide.
Seung‐Uk Shin, Du‐Gyeong Han, Hyung‐Chul Cho, Eun‐Mi Kim, Kyoung‐Seong Choi   +4 more
wiley   +1 more source