Results 51 to 60 of about 40,099 (291)

Revealing the molecular signatures of host-pathogen interactions. [PDF]

open access: yes, 2011
Advances in sequencing technology and genome-wide association studies are now revealing the complex interactions between hosts and pathogen through genomic variation signatures, which arise from evolutionary co ...
C Herdtweck   +53 more
core   +13 more sources

Complete replication of hepatitis C virus in cell culture. [PDF]

open access: yes, 2005
Many aspects of the hepatitis C virus (HCV) life cycle have not been reproduced in cell culture, which has slowed research progress on this important human pathogen.
Burton, Dennis R   +10 more
core   +1 more source

All genera of Flaviviridae host a conserved Xrn1-resistant RNA motif

open access: yesRNA Biology, 2021
After infection by flaviviruses like Zika and West Nile virus, eukaryotic hosts employ the well-conserved endoribonuclease Xrn1 to degrade the viral genomic RNA.
I. W. Dilweg   +5 more
semanticscholar   +1 more source

In vitro and in silico Models to Study Mosquito-Borne Flavivirus Neuropathogenesis, Prevention, and Treatment

open access: yesFrontiers in Cellular and Infection Microbiology, 2019
Mosquito-borne flaviviruses can cause disease in the nervous system, resulting in a significant burden of morbidity and mortality. Disease models are necessary to understand neuropathogenesis and identify potential therapeutics and vaccines.
Megan Chesnut   +10 more
doaj   +1 more source

Replication enhancer elements within the open reading frame of tick-borne encephalitis virus and their evolution within the Flavivirus genus [PDF]

open access: yes, 2011
We provide experimental evidence of a replication enhancer element (REE) within the capsid gene of tick-borne encephalitis virus (TBEV, genus Flavivirus).
Buckley, A.   +5 more
core   +3 more sources

Differential effects of lipid biosynthesis inhibitors on Zika and Semliki Forest viruses [PDF]

open access: yes, 2017
The recent outbreak of infection with Zika virus (ZIKV; Flaviviridae) has attracted attention to this previously neglected mosquito-borne pathogen and the need for efficient therapies.
Donald, Claire L.   +4 more
core   +1 more source

Ultrastructural aspects of virus replication in one fatal case and several other isolates from a dengue type 2 outbreak in Rio de Janeiro

open access: yesMemorias do Instituto Oswaldo Cruz, 1994
Dengue virus replication in mosquito cell cultures was observed by electron microscopy in one fatal and 40 classical isolates from a dengue type 2 outbreak in Rio de Janeiro and compared with the prototype New Guinea C strain.
Ortrud Monika Barth   +3 more
doaj   +1 more source

West Nile Virus Infection

open access: yesPathogens, 2023
West Nile virus (WNV) is a mosquito-borne pathogen that belongs to the Flavivirus genus (family Flaviviridae) [...]
Francisco Llorente
doaj   +1 more source

No Evidence of Mosquito Involvement in the Transmission of Equine Hepacivirus (Flaviviridae) in an Epidemiological Survey of Austrian Horses [PDF]

open access: goldViruses, 2019
Prevalence studies have demonstrated a global distribution of equine hepacivirus (EqHV), a member of the family Flaviviridae. However, apart from a single case of vertical transmission, natural routes of EqHV transmission remain elusive.
Marcha Badenhorst   +8 more
openalex   +2 more sources

Cross-Protection of Dengue Virus Infection against Congenital Zika Syndrome, Northeastern Brazil

open access: yesEmerging Infectious Diseases, 2019
The Zika virus outbreak in Latin America resulted in congenital malformations, called congenital Zika syndrome (CZS). For unknown reasons, CZS incidence was highest in northeastern Brazil; one potential explanation is that dengue virus (DENV)–mediated ...
Celia Pedroso   +10 more
doaj   +1 more source

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