Results 91 to 100 of about 18,525 (157)

Design, development, and validation of multi-epitope proteins for serological diagnosis of Zika virus infections and discrimination from dengue virus seropositivity.

PLoS Neglected Tropical Diseases
Zika virus (ZIKV), an arbovirus from the Flaviviridae family, is the causative agent of Zika fever, a mild and frequent oligosymptomatic disease in humans. Nonetheless, on rare occasions, ZIKV infection can be associated with Guillain-Barré Syndrome (GBS)
Samille Henriques Pereira, Mateus Sá Magalhães Serafim, Thaís de Fátima Silva Moraes, Nathalia Zini, Jônatas Santos Abrahão, Maurício Lacerda Nogueira, Jordana Grazziela Alves Coelho Dos Reis, Flávia Fonseca Bagno, Flávio Guimarães da Fonseca   +8 more
doaj   +1 more source

Emerging Role of l-Dopa Decarboxylase in Flaviviridae Virus Infections

, 2019
l-dopa decarboxylase (DDC) that catalyzes the biosynthesis of bioactive amines, such as dopamine and serotonin, is expressed in the nervous system and peripheral tissues, including the liver, where its physiological role remains unknown.
Kolaitis, N., Kalliampakou, K.I., Kaimou, P., Boleti, H., Vassilacopoulou, D., Vassilaki, N., Frakolaki, E., Moraiti, M., Koskinas, J.   +8 more
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Pan-viral efficacy profile of ribavirin: quantitative potency and safety landscape across virus families [PDF]

Pharmacia
This study quantifies ribavirin’s pan-viral efficacy across seven virus families, compares it with favipiravir and remdesivir, and evaluates viral trait predictors alongside clinical concordance.
Fredmoore Orosco
doaj   +3 more sources

Zika virus infection – a new epidemic threat

Pediatria i Medycyna Rodzinna, 2016
Zika virus, like dengue and yellow fever viruses, is an RNA virus of the Flaviviridae family. The virus is transmitted by Aedes mosquitoes. On February 1, 2016, the World Health Organization declared Zika virus a Public Health Emergency of International
Dominika Pomorska, Ernest Kuchar
doaj   +1 more source

Epidemiological and clinical characteristics of Dengue virus outbreaks in two regions of China, 2014 - 2015.

PLoS ONE, 2019
Dengue virus (DENV), a single-stranded RNA virus and Flaviviridae family member, is transmitted by Aedes aegypti and Aedes albopictus mosquitoes. DENV causes dengue fever, which may progress to severe dengue.
Jiaqi Cao, Hong Deng, Lei Ye, Xuezheng Ma, Shuru Chen, Xiaohong Sun, Xuemin Wu, Tao Yan, Liping Zhang, Lijuan Liu, Lili Li, Wuping Li, Kongxin Hu   +12 more
doaj   +1 more source

A multi-variant, viral dynamic model of genotype 1 HCV to assess the in vivo evolution of protease-inhibitor resistant variants

, 2010
Variants resistant to compounds specifically targeting HCV are observed in clinical trials. A multi-variant viral dynamic model was developed to quantify the evolution and in vivo fitness of variants in subjects dosed with monotherapy of an HCV protease ...
Stefan Zeuzem, Randle, John C. R., Randle John C. R., Lin, Chao, Kwong Ann D., Bambang S Adiwijaya, John C. R. Randle, Sarrazin, Christoph, Paul R. Caron, Herrmann Eva, Zeuzem Stefan, Christoph Sarrazin, Garg Varun, Kieffer, Tara, Brian Hare, Hare, Brian, Varun Garg, Lin Chao, Kieffer Tara, Herrmann, Eva, Caron, Paul R., Kwong, Ann D., Tara Kieffer, Ann D Kwong, Sarrazin Christoph, Chao Lin, Bambang S. Adiwijaya, Adiwijaya, Bambang S., Hare Brian, Paul R Caron, Caron Paul R., Garg, Varun, Eva Herrmann, Ann D. Kwong, John C R Randle, Adiwijaya Bambang S., Zeuzem, Stefan   +36 more
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Iminosugars: A host-targeted approach to combat Flaviviridae infections. [PDF]

Antiviral Res, 2020
Evans DeWald L, Starr C, Butters T, Treston A, Warfield KL.   +4 more
europepmc   +1 more source

Rôle de la glycosylation des protéines d’enveloppe dans la morphogenèse des Flaviviridae et son inhibition par des antiviraux de nouvelles générations

, 2004
Several viruses of the Flaviviridae family are causing agents of human pathologies, including haemorrhagic fever (e.g. Dengue virus, Yellow fever virus), encephalitis (e.g. Japanese encephalitis virus), or chronic hepatitis (Hepatitis C virus).
Vuillermoz, I., Zitzmann, N, Zoulim, F., Durantel, D., Vuillermoz, I, Trépo, C, Chapel, C., Chapel, C, Trépo, C., Zoulim, F, Zitzmann, Nicole, Durantel, D   +11 more
core   +1 more source

Estudo in vitro das citocinas envolvidas na resposta inflamatória de macrófagos murinos à infecção pelo vírus da dengue. [PDF]

, 2012
TCC(graduação) - Universidade Federal de Santa Catarina. Centro de Ciências Biológicas. Biologia.A dengue é uma doença que tem como agente etiológico o Dengue virus (DENV), da família Flaviviridae, do gênero Flavivirus.
Souza, Ingrid Larissa Melo de
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An updated evolutionary study of Flaviviridae NS3 helicase and NS5 RNA-dependent RNA polymerase reveals novel invariable motifs as potential pharmacological targets

, 2016
The rate of Flaviviridae family virus infections worldwide has increased dramatically in the last few years. In addition, infections caused by arthropod vector viruses including Hepatitis C, West Nile, Dengue fever, Yellow fever and Japanese encephalitis
Papageorgiou, L., Loukatou, S., Vlachakis, D., Maroulis, D., Sofia, K.   +4 more
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