Results 81 to 90 of about 18,525 (157)

Toll-Like Receptors and RIG-I-Like Receptors Play Important Roles in Resisting Flavivirus

Journal of Immunology Research, 2018
Flaviviridae family is a class of single-stranded RNA virus, which is fatal to human and animals and mainly prevalent in subtropic and tropic countries.
Hong-Yan Guo, Xing-Cui Zhang, Ren-Yong Jia   +2 more
doaj   +1 more source

Isolation of Metabolites With Antiviral Activity From the Brown Algae Dictyota fasciola and Dictyota mediterranea

Chemistry &Biodiversity, Volume 23, Issue 6, June 2026.
Twenty‐one compounds, including six dolabellanes diterpenes and one germacrene sesquiterpene that are new natural products, are reported from the brown algae Dictyota fasciola and Dictyota mediterranea collected from the Aegean Sea. Among them, some exhibit considerable antiviral activity against RNA (HCoV‐NL63, ZIKV) and DNA (HSV‐1) viruses.
Aikaterini Koutsaviti, Elsi‐Evangelia Andriotaki, Maria Harizani, Katarzyna Owczarek, Magdalena Pachota, Aleksandra Synowiec, Artur Szczepański, Paweł Botwina, Krzysztof Pyrć, Vassilios Roussis, Efstathia Ioannou   +10 more
wiley   +1 more source

ProTides for Antiviral Activity Beyond Liver Cells

Chemistry – A European Journal, Volume 32, Issue 21, 1 June 2026.
A strategy for obtaining prodrugs of antiviral nucleotides with broad tissue activity is presented that relies on cycloalkyl or cycloalkylalkyl esters, improving uptake and esterase cleavage, and producing nanomolar inhibitors in kidney, colon, and lung cells.
Felix Goebel, Adrian Humboldt, Heeyoung Kim, Carl J. M. Schölzel, Ralf Bartenschlager, Clemens Richert   +5 more
wiley   +1 more source

Hepatitis C Virus Infection in the PERSIAN Guilan Cohort Study Population: Intrafamilial Transmission Incidence and Response to SOVODAK‐Based Therapy

Health Science Reports, Volume 9, Issue 6, June 2026.
ABSTRACT Background Hepatitis C virus (HCV) infection is one of the leading causes of liver‐related diseases such as cirrhosis and hepatocellular carcinoma. Despite ongoing efforts, no effective vaccine has been developed to date due to the virus's high mutation rate and extensive genetic variability. This study aimed to determine the prevalence of HCV
Farahnaz Joukar, Sara Yeganeh, Narges Eslami, Fariborz Mansour‐Ghanaei   +3 more
wiley   +1 more source

Differentiation of West Nile and Usutu Virus Infections by Antibodies Directed to the Non-Structural Protein 1

Viruses
The genus Orthoflavivirus (family Flaviviridae) comprises several important pathogens that are widespread across the globe, often co-circulating in many regions.
Lena Roßbacher, Samuel Taschler, Elena Cecchettin, Amelie Popovitsch, Stephan W. Aberle, Judith H. Aberle, Iris Medits-Weiss, Karin Stiasny   +7 more
doaj   +1 more source

The Structural Basis of Flaviviridae Interaction with Antibodies and Receptors

, 2011
Flaviviridae are a family of enveloped, positive-stranded RNA viruses responsible for a variety of diseases including encephalitis, hemorrhagic fever and hepatocellular carcinoma.
Luca, Vincent
core   +1 more source

Current viral infections and epidemics of flaviviridae; lots of grief but also some hope

, 2012
Flaviviridae is a family of RNA viruses that includes numerous important human and animal pathogens. Recent studies on subgenomic flaviviridae replicons have revealed that the non-structural (NS) proteins, which are encoded by the C-terminal part of the ...
Champeris Tsaniras, Spyridon, Kossida, Sophia; Biomedical Research Foundation, Academy of Athens, Athens, Greece, Vlachakis, Dimitrios   +2 more
core  

An in-depth exploration of snake venom-derived molecules for drug discovery in advancing antiviral therapeutics

Heliyon
Snake venom is a cocktail and rich source of various bioactive compounds that have been extensively studied for their potential as pharmaceutical agents due to their diverse chemical structures and wide range of biological activities.
Hicham Hboub, Reda Ben Mrid, Najat Bouchmaa, Naoual Oukkache, Rachid El Fatimy   +4 more
doaj   +1 more source

West Nile Virus Infections in (European) Birds [PDF]

, 2016
West Nile virus (WNV), a member of the Flaviviridae family is an important emerging pathogen transmitted by mosquitoes of the Culex sp . wild-and (peri) domesticated birds act as the natural hosts of WNV.
Martina, Byron EE, BARZON, LUISA, Koraka, Penelope   +2 more
core   +1 more source

Identification of a previously undescribed divergent virus from the Flaviviridae family in an outbreak of equine serum hepatitis

, 2013
Theiler’s disease is an acute hepatitis in horses that is associated with the administration of equine blood products; its etiologic agent has remained unknown for nearly a century.
Divers, Thomas J., Zhong, Weidong, Van Blaricum, Anita J., Tennant, Bud C., Ganem, Donald, Chandriani, Sanjay, Skewes-Cox, Peter, Kistler, Amy   +7 more
core   +1 more source