Results 91 to 100 of about 3,670,778 (207)

Membrane‐Permeable Nucleoside T‐1106 Diphosphate and Triphosphate Analogues as Antiviral Pronucleotides

Chemistry – A European Journal, EarlyView.
Favipiravir (T‐705) and the non‐fluorinated counterpart (T‐1106) are antiviral agents that inhibit the RNA‐dependent RNA polymerase (RdRp) of various RNA viruses. The antiviral efficacy of nucleoside analogues is strongly dependent on their intracellular activation by cellular kinases to produce their corresponding triphosphate metabolites (T‐705‐RTP ...
Chris Meier, Duan Li, Leentje Persoons, Graciela Andrei, Robert Snoeck, Dominique Schols, Lieve Naesens, Xiao Jia   +7 more
wiley   +1 more source

Diagnosis of Fatal Human Case of St. Louis Encephalitis Virus Infection by Metagenomic Sequencing, California, 2016

Emerging Infectious Diseases, 2017
We used unbiased metagenomic next-generation sequencing to diagnose a fatal case of meningoencephalitis caused by St. Louis encephalitis virus in a patient from California in September 2016.
Charles Y. Chiu, Lark L. Coffey, Jamie Murkey, Kelly Symmes, Hannah A. Sample, Michael R. Wilson, Samia N. Naccache, Shaun Arevalo, Sneha Somasekar, Scot Federman, Doug Stryke, Paul Vespa, Gary Schiller, Sharon Messenger, Romney Humphries, Steve Miller, Jeffrey D. Klausner   +16 more
doaj   +1 more source

Retrospective identification of human cases of West Nile virus infection in Austria (2009 to 2010) by serological differentiation from Usutu and other flavivirus infections.

Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin, 2013
There is increasing evidence for the spread of West Nile virus (WNV) in southern, eastern and central Europe. In parallel, another flavivirus, the antigenically closely related Usutu virus, was introduced from Africa and first detected in Austria (2001),
K. Stiasny, S. Aberle, F. Heinz
semanticscholar   +1 more source

Does a decision support tool designed to depict West Nile virus risk explain variation in ruffed grouse Bonasa umbellus use of managed forests?

Wildlife Biology, EarlyView.
Infectious diseases are commonly cited as significant contributors to wildlife population declines. It is, therefore, important to investigate the extent to which tools designed to mitigate the effects of infectious diseases explain wildlife responses to habitat management.
Jacob Goldman, Darin J. McNeil, Lauren M. Chronister, Randall Koleck, Samuel Lapp, Jeffery T. Larkin, Reina Tyl, Justin Kitzes, Jeffery L. Larkin   +8 more
wiley   +1 more source

Tick‐Borne Encephalitis (TBE) Vaccine in the National Immunisation Programme—For Whom, When and Where?

Acta Paediatrica, EarlyView.
ABSTRACT The incidence of Tick‐borne encephalitis (TBE) cases has increased. The presumed location of transmission of Tick‐borne encephalitis virus (TBEV) has been expanding increasingly in the western parts of Europe during the past decade. There has also been an increased incidence of surveillance‐reported TBE cases in southern Sweden and southern ...
H. H. Askling, D. Zavadska
wiley   +1 more source

The Multifaceted Roles of Autophagy in Flavivirus-Host Interactions

, 2018
Autophagy is an evolutionarily conserved cellular process in which intracellular components are eliminated via lysosomal degradation to supply nutrients for organelle biogenesis and metabolic homeostasis.
Po-Yuan Ke
core   +1 more source

Universal primers that amplify RNA from all three flavivirus subgroups [PDF]

, 2008
Background: Species within the Flavivirus genus pose public health problems around the world. Increasing cases of Dengue and Japanese encephalitis virus in Asia, frequent outbreaks of Yellow fever virus in Africa and South America, and the ongoing spread
Gibbs, Mark J., Maher-Sturgess, Sheryl L, Wayper, Paul, Barnard Ross T, Roy A Hall, Naomi L Forrester, Forrester, Naomi L, Paul J Wayper, Wayper, Paul J., Ernest A Gould, Gibbs, Mark, Gould, Ernest A., Hall, Roy A., Gould Ernest A, Barnard, Ross T., Forrester Naomi L, Gould, Ernest A, Forrester, Naomi L., Hall, Roy A, Hall Roy A, Gibbs Mark J, Mark J Gibbs, Maher-Sturgess, Sheryl L., Barnard, Ross T, Wayper Paul J, Sheryl L Maher-Sturgess, Ross T Barnard, Maher-Sturgess Sheryl L   +27 more
core   +1 more source

Vectors and Vector‐Borne Diseases: Biology, Epidemiology and Integrated Control Strategies

Journal of Applied Entomology, EarlyView.
ABSTRACT Vector‐Borne Diseases (VBDs), transmitted by arthropods such as mosquitoes, ticks, fleas and sandflies, represent a significant threat to global health. These diseases can be caused by a variety of pathogens, including bacteria, viruses, protozoa, and helminths.
Roberta Rinaldi, Carmen Scieuzo, Federica De Stefano, Luca Masucci, Patrizia Falabella   +4 more
wiley   +1 more source

Pooled prevalence estimates of comorbidities in severe and non-severe cases of flavivirus infections dengue fever and West Nile virus.

, 2018
Pooled prevalence estimates of comorbidities in severe and non-severe cases of flavivirus infections dengue fever and West Nile virus.
Arrani Senthinathan (5497523), Mikayla Plishka (5497541), Russanthy Velummailum (5497529), Sahar Yaghoubi (5497532), Denitsa Vasileva (5497535), Paul Arora (141025), Marcel Soosaipillai (5497544), Emma Ostermeier (5497538), Alaa Badawi (521535), Seung Gwan Ryoo (5497526)   +9 more
core   +1 more source

Dengue virus activates polyreactive, natural IgG B cells after primary and secondary infection. [PDF]

, 2011
BACKGROUND: Dengue virus is transmitted by mosquitoes and has four serotypes. Cross-protection to other serotypes lasting for a few months is observed following infection with one serotype.
Low, Jenny G., Bela-Ong, D.B., Gu, F., Martin L. Hibberd, Fink, Katja, Mickey B Koh, Hibberd, Martin, L, Martin L Hibberd, Katja Fink, Ooi Eng Eong, Leo Yee Sin, Toh, Ying, Xiu, Balakrishnan, Thavamalar, Jenny G Low, Leo, Yee Sin, Balakrishnan, T., Devi, S., Toh Ying Xiu, Dennis B Bela-Ong, Marie Flamand, Flamand, M., Hibberd, Martin L., Flamand, Marie, Leo, Y.S., Flamand Marie, Devi Shamala, Bela-Ong, Dennis, B, Thavamalar Balakrishnan, Yee Sin Leo, Fink Katja, Fink, K., Hibberd, M.L., Jenny G. Low, Ying Xiu Toh, Ooi, E.E., Toh, Y.X., Gu Feng, Ooi, Eng, Eong, Leo, Yee, Sin, Koh, Mickey B., Hibberd Martin L., Bela-ong, Dennis B., Koh, Mickey, B, Eng Eong Ooi, Feng Gu, Low, J.G., Dennis B. Bela-Ong, Balakrishnan Thavamalar, Low, Jenny G, Low Jenny G., Shamala Devi, Toh, Ying Xiu, Bela-Ong, Dennis B, Low, Jenny, G, Mickey B. Koh, Koh Mickey B., Devi, Shamala, Ooi, Eng Eong, Hibberd, Martin L, Koh, M.B., Bela-Ong Dennis B., Koh, Mickey B, Gu, Feng   +62 more
core   +1 more source