Results 91 to 100 of about 30,996 (190)

Identification and Optimization of a Truncated Hs‐1‐Derived Antimicrobial Peptide for Enhanced Broad‐Spectrum Antiviral Activity

ChemMedChem, Volume 21, Issue 13, 14 July 2026.
Can a shorter peptide be a better antiviral? Structure‐guided optimization of the amphibian peptide Hs‐1 reveals a minimal α‐helical core that, after terminal modification, displays enhanced stability and submicromolar broad‐spectrum activity against enveloped viruses while maintaining a favorable safety profile. Antimicrobial peptides (AMPs) represent
Carla Zannella, Annalisa Chianese, Rosa Giugliano, Roberta Della Marca, Alessandra Monti, Martina Dragone, Gaetano Malgieri, Nunzianna Doti, Carla Isernia, Anna De Filippis, Massimiliano Galdiero   +10 more
wiley   +1 more source

Spot the Difference—Development of a Syndrome Based Protein Microarray for Specific Serological Detection of Multiple Flavivirus Infections in Travelers [PDF]

, 2015
The family Flaviviridae, genus Flavivirus, holds many of the world’s most prevalent arboviral diseases that are also considered the most important travel related arboviral infections. In most cases, flavivirus diagnosis in travelers is primarily based on
Velasco-Salas, Z. I., Goeijenbier, M. (Marco), Johnson, Barbara W., Reimerink, Johan, Chantal B E M Reusken, Tami, A., Doorn, H.R. (H. Rogier van), Sambri, V, Velasco-Salas, Z.I. (Zoraida I.), Reusken, CBEM, Cleton, Natalie, Koopmans, Marion P. G., Velasco-Salas, Zoraida L., Godeke, Gert-Jan, Beersma, M. F., Sambri, V., Beersma, Mathias F., Cleton, Natalie B, Goeijenbier, M, Vittorio Sambri, Doorn, H. Rogier van, Jiménez-Clavero, Miguel Ángel, Jiménez-Clavero, M.A., Cleton, Natalie B., Niedrig, M, Godeke, G-J. (Gert-Jan), Koopmans D.V.M., M.P.G. (Marion), Koopmans, M. P. G., Johan Reimerink, Niedrig, M., Reusken, C. B. E. M., Mathias F Beersma, Koopmans, MPG, Marco Goeijenbier, H Rogier van Doorn, Koopmans, Mp, Cleton, Nb, Velasco-Salas, Zoraida I, van Doorn, HR, Sambri, V. (Vittorio), Tami, Adriana, Miguel A Jimenez-Clavero, Anna Papa, Zoraida I Velasco-Salas, Franco, L, Godeke, G-J, Jimenez-Clavero, MA, Goeijenbier, M., Tami, Adriana; id_orcid, van Doorn, H. Rogier, Reusken, Chantal, Godeke, G. J., Marion P G Koopmans, Franco, L., Reimerink, J, Johnson, B. W., Tami, A. (Adriana), Papa, A, Tami, A, Adriana Tami, Johnson, Bw, Velasco-Salas, ZI, Beersma, Mathias F, Gert-Jan Godeke, Godeke, Gj, Reusken, C.B.E.M. (Chantal), Niedrig, Matthias, Franco, Leticia, Beersma, Mf, Reusken, Cb, Beersma, Thijs, Koopmans, Marion P G, Doorn, Hr, Reusken, Chantal B E M, Johnson, B.W. (Barbara W.), Goeijenbier, Marco, Cleton, N. B., Beersma, M.F.C. (Thijs), Jimenez Clavero, Ma, Velasco-Salas, Zoraida I., Matthias Niedrig, Doorn, HRV, Velasco Salas, Zi, Franco, L. (Leticia), Natalie B Cleton, Doorn, H Rogier van, Cleton, N.B. (Natalie), Reimerink, J.H.J. (Johan), Jimenez-Clavero, Miguel A., Leticia Franco, Reimerink, J., Day, NP, Koopmans, Marion, Johnson, Barbara W, Papa, A. (Anna), Doorn, H. R., Papa, Anna, Reusken, Chantal B. E. M., Barbara W Johnson, Sambri, Vittorio   +99 more
core   +1 more source

The Regulation of Flavivirus Infection by Hijacking Exosome-Mediated Cell–Cell Communication: New Insights on Virus–Host Interactions

Viruses, 2020
The arthropod-borne flaviviruses are important human pathogens, and a deeper understanding of the virus–host cell interaction is required to identify cellular targets that can be used as therapeutic candidates.
José Manuel Reyes-Ruiz, Juan Fidel Osuna-Ramos, Luis Adrián De Jesús-González, Selvin Noé Palacios-Rápalo, Carlos Daniel Cordero-Rivera, Carlos Noe Farfan-Morales, Arianna Mahely Hurtado-Monzón, Carla Elizabeth Gallardo-Flores, Sofía L. Alcaraz-Estrada, Juan Santiago Salas-Benito, Rosa María del Ángel   +10 more
doaj   +1 more source

Le remodelage morphologique et fonctionnel du cytoplasme par les flavivirus [PDF]

Les infections par les flavivirus constituent un enjeu de santé publique majeur dans le monde avec dans la plupart des cas aucun traitement antiviral disponible.
Chatel-Chaix, Laurent
core  

A Novel Model for the Study of the Therapy of Flavivirus Infections Using the Modoc Virus [PDF]

, 2001
The murine Flavivirus Modoc replicates well in Vero cells and appears to be as equally sensitive as both yellow fever and dengue fever virus to a selection of antiviral agents.
Leyssen, Pieter, De Clercq, Erik, Drosten, Christian, Johan Neyts, De Clercq E, Pieter Leyssen, Van Lommel, Alfons, Schmitz, Herbert, Erik De Clercq, Schmitz, H., Christian Drosten, Neyts, Johan, Alfons Van Lommel, Drosten, C., Herbert Schmitz   +14 more
core   +1 more source

The Challenges of Flavivirus Drug Discovery [PDF]

, 2011
Many flaviviruses are human pathogens of global importance, but no antiviral medicines are currently available to manage these diseases. Over the past decade, significant progress has been made towards the understanding of flavivirus biology.
Qing-Yin Wang, Pei-Yong Shi, Thomas H. Keller   +2 more
core   +1 more source

Analysis of Molecular Interactions Between West Nile Virus and Host Cells [PDF]

Members of the genus Flavivirus are positive-stand RNA viruses that can cause a variety of human diseases, including fever, encephalitis, hepatitis and hemorrhagic fevers.
Espinola Estigarribia, Emilio
core   +1 more source

DEVELOPMENT OF A MODEL FOR SURVEILLANCE AND CONTROL OF FLAVIVIRUSES IN HUMAN POPULATION

Archives of Veterinary Medicine, 2015
The aim of this study is development of a model for monitoring and control of vector-transmitted diseases, which manifest increasing tendency during the last few decades.
Vesna Milošević, Sandra Stefan Mikić, Dušan Petrić, Tamaš Petrović, Jelena Radovanov, Gordana Kovačević, Ivana Hrnjaković Cvjetković   +6 more
doaj   +1 more source

Role of pattern recognition receptors in flavivirus infections [PDF]

, 2014
The flaviviral encephalitis has now become a major health concern in global scale. The efficient detection of viral infection and induction of the innate antiviral response by host's innate immune system are crucial to determine the outcome of infection.
Basu, Anirban, Hazra, Bibhabasu, Dutta, Kallol, Nazmi, Arshed   +3 more
core   +1 more source

New developments in flavivirus drug discovery [PDF]

, 2016
Introduction: Flaviviruses are major causes of infectious disease. The vast global, social and economic impact due to morbidity and mortality associated with diseases caused by these viruses urgently demands effective therapeutic interventions.
Kok, W. Mei
core   +1 more source