Results 101 to 110 of about 30,996 (190)

Implicações do peptídeo conservado E250-270 da proteína "E" na infectividade do vírus da dengue [PDF]

, 2014
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Biotecnologia e Biociências, Florianópolis, 2014Os vírus de genoma RNA apresentam uma ampla variabilidade genética, devido à ...
Fleith, Renata Cristina
core  

[New approaches to the treatment of the flavivirus infections].

Voprosy virusologii, 2015
Since spontaneous mutagenesis and quasi-species rearrangements of the RNA-containing viruses, as well as an absence of both viral and cellular RNA reparation systems, causes resistance to originally effective antiviral drugs, combination therapy with nucleoside and non-nucleoside inhibitors of the viral enzymes in combination with immunomodulators is ...
Morozova, Olga Vladimirovna, Isaeva, Elena I., Viazov, Sergei O.   +2 more
openaire   +2 more sources

High‐throughput peptide array analysis and computational techniques for serological profiling of flavivirus infections: Implications for diagnostics and vaccine development [PDF]

Arthropod-borne viruses, such as dengue virus (DENV), pose significant global health threats, with DENV alone infecting around 400 million people annually and causing outbreaks beyond endemic regions. This study aimed to enhance serological diagnosis and
Grifantini, Renata, Abrignani, Sergio, Baldanti, Fausto, Percivalle, Elena, Bombaci, Mauro, Pesce, Elisa, Cassaniti, Irene, Gismondo, Maria Rita, Mileto, Davide, Colombo, Giorgio, Sammartino, Jose', Ferrari, Alessandro, Grande, Romualdo, Gobbini, Andrea, Marchisio, Edoardo, Fassi, Enrico Mario Alessandro, Casali, Emanuele, Mancon, Alessandro   +17 more
core   +1 more source

Proposed algorithm of using multiplex NS1 IgG MIA to distinguish three flavivirus infections. [PDF]

, 2019
Based on positivity to NS1 proteins of three serocomplexes (DENV [DENV1, 2, 3 or 4], ZIKV and WNV NS1), the samples that were negative to all NS1 proteins or positive to NS1 protein of one serocomplex (DENV, ZIKV or WNV) could be flavivirus naïve or ...
Jasmine Tyson (5892029), Ludvig Mässgård (7305194), Jih-Jin Tsai (189820), Axel T. Lehrer (5944625), Wei-Kung Wang (108070), Susan L. Stramer (7305197), Vivek R. Nerurkar (7305200), Wen-Yang Tsai (108058)   +7 more
core   +1 more source

Efficient transplacental IgG transfer in women infected with Zika virus during pregnancy.

PLoS Neglected Tropical Diseases, 2019
Zika virus (ZIKV) is a newly-identified infectious cause of congenital disease. Transplacental transfer of maternal IgG to the fetus plays an important role in preventing many neonatal infections.
Tulika Singh, Cesar A Lopez, Camila Giuberti, Maria L Dennis, Hannah L Itell, Holly J Heimsath, Helen S Webster, Hunter K Roark, Paulo R Merçon de Vargas, Allison Hall, Ralph G Corey, Geeta K Swamy, Reynaldo Dietze, Helen M Lazear, Sallie R Permar   +14 more
doaj   +1 more source

Signal transduction in immune cells and extracellular matrix role in viral tick-borne encephalitis

Инфекция и иммунитет
Tick-borne encephalitis virus, a member of the genus Orthoflavivirus, consisting of Flaviviridae, is the causative agent of tick-borne encephalitis, a neuroviral disease, the severity of which varies from mild (febrile form) to severe and life ...
Jeanne P. Belokrylova
doaj   +1 more source

Detection of specific ZIKV IgM in travelers using a multiplexed flavivirus microsphere immunoassay [PDF]

, 2018
Zika virus (ZIKV) has spread widely in the Pacific and recently throughout the Americas. Unless detected by RT-PCR, confirming an acute ZIKV infection can be challenging.
Carmel Taylor, Moore, Peter R., Jamie McMahon, Sarah L. Wheatley, Sarah Wheatley, McMahon, Jamie L., Glen Hewitson, Ian Mackay, Frederick Moore, Taylor, Carmel T., Hewitson, Glen R., Wheatley, Sarah L., Peter Moore, Finger, Mitchell J., Moore, Frederick A., Jamie L. McMahon, Mackay, Ian M., Ian M. Mackay, Peter R. Moore, Mitchell J. Finger, Frederick A. Moore, Glen R. Hewitson, Mitchell Finger, Carmel T. Taylor   +23 more
core   +1 more source

Molecular and Cellular Mechanisms Underlying Neurologic Manifestations of Mosquito-Borne Flavivirus Infections. [PDF]

Viruses, 2023
Blackhurst BM, Funk KE.
europepmc   +1 more source

Cholesterol-Lowering Drugs as Potential Antivirals: A Repurposing Approach against Flavivirus Infections. [PDF]

Viruses, 2023
Osuna-Ramos JF, Farfan-Morales CN, Cordero-Rivera CD, De Jesús-González LA, Reyes-Ruiz JM, Hurtado-Monzón AM, Palacios-Rápalo SN, Jiménez-Camacho R, Meraz-Ríos MA, Del Ángel RM.   +9 more
europepmc   +1 more source

The glycosylation deficiency of flavivirus NS1 attenuates virus replication through interfering with the formation of viral replication compartments

Journal of Biomedical Science
Background Flavivirus is a challenge all over the world. The replication of flavivirus takes place within membranous replication compartments (RCs) derived from endoplasmic reticulum (ER).
Shuhan Huang, Pan-Deng Shi, Xiao-Xuan Fan, Yang Yang, Cheng-Feng Qin, Hui Zhao, Lei Shi, Yali Ci   +7 more
doaj   +1 more source