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Intrinsically disordered protein domains in flavivirus infection
Archives of Biochemistry and Biophysics, 2020Intrinsically disordered protein regions are at the core of biological processes and involved in key protein-ligand interactions. The Flavivirus proteins, of viruses of great biomedical importance such as Zika and dengue viruses, exemplify this. Several proteins of these viruses have disordered regions that are of the utmost importance for biological ...
Ivo C, Martins, Nuno C, Santos
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Dynamics of Flavivirus Infection in Mosquitoes
2003Abstract Mosquito-borne flaviviruses are emerging as the cause of some of the most serious and widespread arthropod-borne viral diseases in the world. Flavivirus outbreaks are influenced by intrinsic (e.g., viral strain, vector competence, host susceptibility) and extrinsic (e.g., temperature, rainfall, human land use) factors that affect mosquito ...
Laura D, Kramer, Gregory D, Ebel
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Serological Detection of Flavivirus Infections in Saudi Baboons
EcoHealth, 2021To evaluate the risk to public health from Flaviviruses in the southwest region of the Kingdom of Saudi Arabia, we screened as sentinels, 50 commensal hamadryas baboons located at a peri-domestic site on the outskirts of Ta'if City in February 2013. Of the baboons, 12% [95% CI 5, 24], 0% [95% CI 0, 7] and 10% [95% CI 3, 22] were seropositive in a pan ...
Ayodeji Oluwadare Olarinmoye +8 more
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Polarization of avian macrophages upon avian flavivirus infection
Veterinary Microbiology, 2021Avian Tembusu virus (TMUV) is a newly emerging avian pathogenic flavivirus that spreads rapidly, has an expanding host range and undergoes cross-species transmission. Our previous study identified avian monocytes/macrophages as the key targets of TMUV infection, since the infection of host monocytes/macrophages was crucial for the replication ...
Lu, Cui +10 more
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Nucleic acid-based inhibition of flavivirus infections
Frontiers in Bioscience, 2008The genus Flavivirus in the family Flaviviridae consists of many arthropod-transmitted human pathogens, including dengue, yellow fever, Japanese encephalitis, West Nile, St. Louis encephalitis, Murray Valley encephalitis, and tick-borne encephalitis viruses. Treatment options against flaviviral disease are extremely limited, with no effective drugs yet
David A, Stein, Pei-Yong, Shi
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Antibody Prophylaxis and Therapy for Flavivirus Encephalitis Infections
Annals of the New York Academy of Sciences, 2001Abstract: The outbreak of West Nile (WN) encephalitis in the United States has rekindled interest in developing direct methods for prevention and control of human flaviviral infections. Although equine WN vaccines are currently being developed, a WN vaccine for humans is years away. There is also no specific therapeutic agent for flaviviral infections.
J T, Roehrig +4 more
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Dengue and other flavivirus infections.
Revue scientifique et technique (International Office of Epizootics), 2015Flaviviruses are responsible for yellow fever, Zika fever and dengue, all of which are major human diseases found in tropical regions of the globe. They are zoonoses with a transmission cycle that involves primates as reservoirs and mosquitoes of the genus Aedes as vectors.
Choumet, Valérie, Desprès, Philippe
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La dengue et autres infections à flavivirus
Revue Scientifique et Technique de l'OIE, 2015Flaviviruses are responsible for yellow fever, Zika fever and dengue, all of which are major human diseases found in tropical regions of the globe. They are zoonoses with a transmission cycle that involves primates as reservoirs and mosquitoes of the genus Aedes as vectors.
V. CHOUMET, P. DESPRES
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Reducing uncertainty about flavivirus infections
The Lancet Infectious Diseases, 2017Adam, Kucharski, Steven, Riley
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Diagnostics of human flavivirus infections
Knjiga sažetaka: Ptičji flavivirusi u kontekstu "Jednog zdravlja" – Epidemiologija, klinička slika i dijagnostikaZbog preklapanja geografske rasprostranjenosti i nespecifičnih kliničkih simptoma, dijagnozu flavivirusnih infekcija potrebno je potvrditi virološkim metodama. Prema Europskom centru za kontrolu i prevenciju bolesti (European Centre for Disease Control and Prevention; ECDC), laboratorijski kriteriji za potvrdu bolesti uključuju: izolaciju virusa u ...
Vilibić Čavlek, Tatjana +5 more
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