Results 91 to 100 of about 33,331 (204)
Deconvolution of pro- and antiviral genomic responses in Zika virus-infected and bystander macrophages. [PDF]
Genome-wide investigations of host-pathogen interactions are often limited by analyses of mixed populations of infected and uninfected cells, which lower sensitivity and accuracy.
Benner, Christopher +9 more
core
Dolphin Morbillivirus in Eurasian Otters, Italy [PDF]
We report biomolecular evidence of dolphin morbillivirus in 4 wild Eurasian otters (Lutra lutra) from southern Italy; 2 animals showed simultaneous immunohistochemical reactivity against morbilliviral antigen.
Cafiero, Maria Assunta +13 more
core +1 more source
The Role of Companion Animals as ‘Sentinels’ From the One Health Perspective
One Health emphasizes the interconnection of human, animal and environmental health. As emotional extensions of humans, companion dogs and cats can serve as sentinels, detecting hazards that can help protect human health from the One Health perspective. When symptoms appear in pets, owners should notice the changes that may pose risks to both human and
Shenchen Kang, Yu Chen, Mengmeng Liu
wiley +1 more source
Spectrum of Viral Pathogens in Blood of Malaria-Free Ill Travelers Returning to Canada
Malaria is the most common specific cause of fever in returning travelers, but many other vectorborne infections and viral infections are emerging and increasingly encountered by travelers.
Ruwandi Kariyawasam +6 more
doaj +1 more source
The Restrictome of Flaviviruses
Flaviviruses are a genus of mostly arthropod-borne RNA viruses that cause a range of pathologies in humans. Basic knowledge on flaviviruses is rapidly expanding, partly due to their status as frequent emerging or re-emerging pathogens. Flaviviruses include the dengue, Zika, West Nile, tick-borne encephalitis and yellow fever viruses (DENV, ZIKV, WNV ...
openaire +3 more sources
NAD+ Homeostasis Attenuates Japanese Encephalitis Virus Infection Progression
JEV infection in brain tissue triggers inflammation and stress in neuronal cells, leading to NAD+ depletion via the overactivation of PARPs and SIRTs. While compensatory biosynthetic pathways (de novo and salvage) were upregulated, the NAD+ level fell critically. In vitro NAMPT inhibition exacerbates this deficit and viral load.
Takele Adugna Kassegn +10 more
wiley +1 more source
Adugna Endale,1,2 Girmay Medhin,1 Koyamo Darfiro,3 Nigatu Kebede,1 Mengistu Legesse1 1Aklilu Lemma Institute of Pathobiology, Addis Ababa University, Addis Ababa, Ethiopia; 2School of Medicine, College of Medicine and Health Sciences, Dire Dawa ...
Endale A +4 more
doaj
Identification of Novel Natural Products as Effective and Broad-Spectrum Anti-Zika Virus Inhibitors
Zika virus (ZIKV) infection during pregnancy leads to severe congenital Zika syndrome, which includes microcephaly and other neurological malformations.
Yaning Gao +7 more
doaj +1 more source
Specific detection of dengue and Zika virus antibodies using envelope proteins with mutations in the conserved fusion loop [PDF]
Detection of antibodies is widely used for the diagnosis of infections with arthropod-borne flaviviruses including dengue (DENV) and Zika virus (ZIKV). Due to the emergence of ZIKV in areas endemic for DENV, massive co-circulation is observed and methods
Barzon, Luisa +12 more
core +2 more sources
Introduction: Dengue virus (DENV) remains a global health threat, with four distinct serotypes (DENV1-4) that complicate vaccine development due to low-affinity, cross-reactive antibodies that increase the risk of antibody-dependent enhancement (ADE ...
Dominik A. Rothen +11 more
doaj +1 more source

