Results 51 to 60 of about 26,788 (261)
Nature Communications, 2021 Subgenomic flaviviral RNAs (sfRNAs) are virus-derived noncoding RNAs produced by pathogenic mosquito-borne flaviviruses (MBF) to counteract the host antiviral response.
A. Slonchak +12 more
semanticscholar +1 more source
The thermal stability of yellow fever vaccines
Memorias do Instituto Oswaldo Cruz, 1990 The assessment of yellow fever vaccine thermostability both in lyophilized form and after reconstitution were analyzed. Two commercial yellow fever vaccines were assayed for their thermal stability. Vaccines were exposed to test temperatures in the range
Ricardo Ishak, Colin R. Howard
doaj +1 more source
Dengue, Yellow Fever, Zika and Chikungunya epidemic arboviruses in Brazil: ultrastructural aspects [PDF]
Memorias do Instituto Oswaldo Cruz, 2021 BACKGROUND The impact of arbovirus cocirculation in Brazil is unknown. Dengue virus (DENV) reinfection may result in more intense viraemia or immunopathology, leading to more severe disease.
Debora Ferreira Barreto-Vieira +4 more
doaj +1 more source
Broadly neutralizing monoclonal antibodies protect against multiple tick-borne flaviviruses
Journal of Experimental Medicine, 2021 VanBlargan et al. describe a novel panel of neutralizing monoclonal antibodies against the emerging tick-borne Powassan virus, including domain III– and fusion loop–binding cross-reactive antibodies that confer broad protection in vivo against Powassan ...
L. VanBlargan +15 more
semanticscholar +1 more source
The Restrictome of Flaviviruses
Virologica Sinica, 2020 Flaviviruses are a genus of mostly arthropod-borne RNA viruses that cause a range of pathologies in humans. Basic knowledge on flaviviruses is rapidly expanding, partly due to their status as frequent emerging or re-emerging pathogens. Flaviviruses include the dengue, Zika, West Nile, tick-borne encephalitis and yellow fever viruses (DENV, ZIKV, WNV ...
openaire +3 more sources
Flaviviruses: braking the entering [PDF]
Current Opinion in Virology, 2013 Flaviviruses are small spherical virus particles covered by a dense icosahedral array of envelope (E) proteins that mediate virus attachment to cells and the fusion of viral and cellular membranes. Our understanding of the mechanism by which flavivirus E proteins orchestrate entry into cells has been advanced by studies of E structure and arrangement ...
Theodore C, Pierson, Margaret, Kielian
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Membrane curvature in flaviviruses [PDF]
Journal of Structural Biology, 2013 Coordinated interplay between membrane proteins and the lipid bilayer is required for such processes as transporter function and the entrance of enveloped viruses into host cells. In this study, three-dimensional cryo-electron microscopy density maps of mature and immature flaviviruses were analyzed to assess the curvature of the membrane leaflets and ...
Wei, Zhang +4 more
openaire +2 more sources
Replicon RNA Viral Vectors as Vaccines
Vaccines, 2016 Single-stranded RNA viruses of both positive and negative polarity have been used as vectors for vaccine development. In this context, alphaviruses, flaviviruses, measles virus and rhabdoviruses have been engineered for expression of surface protein ...
Kenneth Lundstrom
doaj +1 more source
Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes
Advanced Functional Materials, EarlyView.Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth +2 more
wiley +1 more source
Zika Virus Vaccines: Challenges and Perspectives
Vaccines, 2018 Zika virus is an arbovirus that has rapidly spread within the Americas since 2014, presenting a variety of clinical manifestations and neurological complications resulting in congenital malformation, microcephaly, and possibly, in male infertility. These
Raquel das Neves Almeida +3 more
doaj +1 more source