Results 51 to 60 of about 40,077 (289)
Chimeric Yellow Fever/Dengue Virus as a Candidate Dengue Vaccine: Quantitation of the Dengue Virus-Specific CD8 T-Cell Response [PDF]
, 2000 We have constructed a chimeric yellow fever/dengue (YF/DEN) virus, which expresses the premembrane (prM) and envelope (E) genes from DEN type 2 (DEN-2) virus in a YF virus (YFV-17D) genetic background. Immunization of BALB/c mice with this chimeric virus
Ahmed, Rafi +3 more
core +2 more sources
Broadly neutralizing monoclonal antibodies protect against multiple tick-borne flaviviruses
Journal of Experimental Medicine, 2021 VanBlargan et al. describe a novel panel of neutralizing monoclonal antibodies against the emerging tick-borne Powassan virus, including domain III– and fusion loop–binding cross-reactive antibodies that confer broad protection in vivo against Powassan ...
L. VanBlargan +15 more
semanticscholar +1 more source
Replicon RNA Viral Vectors as Vaccines
Vaccines, 2016 Single-stranded RNA viruses of both positive and negative polarity have been used as vectors for vaccine development. In this context, alphaviruses, flaviviruses, measles virus and rhabdoviruses have been engineered for expression of surface protein ...
Kenneth Lundstrom
doaj +1 more source
Presence of Segmented Flaviviruses in Wild Rodents, Pennsylvania, USA
Emerging Infectious Diseases, 2020 Identifying viruses in synanthropic animals is necessary for understanding the origin of many viruses that can infect human hosts and developing strategies to prevent new zoonotic infections.
Arvind Kumar +7 more
doaj +1 more source
Zika Virus Vaccines: Challenges and Perspectives
Vaccines, 2018 Zika virus is an arbovirus that has rapidly spread within the Americas since 2014, presenting a variety of clinical manifestations and neurological complications resulting in congenital malformation, microcephaly, and possibly, in male infertility. These
Raquel das Neves Almeida +3 more
doaj +1 more source
Replication enhancer elements within the open reading frame of tick-borne encephalitis virus and their evolution within the Flavivirus genus [PDF]
, 2011 We provide experimental evidence of a replication enhancer element (REE) within the capsid gene of tick-borne encephalitis virus (TBEV, genus Flavivirus).
Buckley, A. +5 more
core +3 more sources
Chimeric Vaccines Based on Novel Insect-Specific Flaviviruses
Vaccines, 2021 Vector-borne flaviviruses are responsible for nearly half a billion human infections worldwide each year, resulting in millions of cases of debilitating and severe diseases and approximately 115,000 deaths.
J. Harrison +3 more
semanticscholar +1 more source
Frontiers in Microbiology, 2018 Flaviviruses are arboviruses, which comprises more than 70 viruses, covering broad geographic ranges, and responsible for significant mortality and morbidity globally. Due to the lack of efficient inhibitors targeting flaviviruses, the designing of novel
Akanksha Rajput, Manoj Kumar
doaj +1 more source
Zika virus and the never-ending story of emerging pathogens and transfusion medicine [PDF]
, 2016 In the last few years, the transfusion medicine community has been paying special attention to emerging vector-borne diseases transmitted by arboviruses.
Grazzini, Giuliano +4 more
core +1 more source
Insects, 2021 Simple Summary The presence of flavivirus-specific antibodies in neotropical non-human primates (NPs) (i.e., dengue virus) is well known. However, it is unclear if dengue virus or other flaviviruses could be maintained in sylvatic cycles. We detected the
A. Chaves +6 more
semanticscholar +1 more source