Results 81 to 90 of about 26,788 (261)

Flavivirus Receptors: Diversity, Identity, and Cell Entry

Frontiers in Immunology, 2018
Flaviviruses are emerging and re-emerging arthropod-borne pathogens responsible for significant mortality and morbidity worldwide. The genus comprises more than seventy small, positive-sense, single-stranded RNA viruses, which are responsible for a ...
Mathilde Laureti, Mathilde Laureti, Divya Narayanan, Divya Narayanan, Julio Rodriguez-Andres, Julio Rodriguez-Andres, John K. Fazakerley, John K. Fazakerley, Lukasz Kedzierski, Lukasz Kedzierski   +9 more
doaj   +1 more source

The bright and the dark side of human antibody responses to flaviviruses: lessons for vaccine design

EMBO Reports, 2017
Zika and dengue viruses belong to the Flavivirus genus, a close group of antigenically related viruses that cause significant arthropod‐transmitted diseases throughout the globe.
F. Rey, K. Stiasny, M. Vaney, M. Dellarole, F. Heinz   +4 more
semanticscholar   +1 more source

Does a decision support tool designed to depict West Nile virus risk explain variation in ruffed grouse Bonasa umbellus use of managed forests?

Wildlife Biology, EarlyView.
Infectious diseases are commonly cited as significant contributors to wildlife population declines. It is, therefore, important to investigate the extent to which tools designed to mitigate the effects of infectious diseases explain wildlife responses to habitat management.
Jacob Goldman, Darin J. McNeil, Lauren M. Chronister, Randall Koleck, Samuel Lapp, Jeffery T. Larkin, Reina Tyl, Justin Kitzes, Jeffery L. Larkin   +8 more
wiley   +1 more source

Tick‐Borne Encephalitis (TBE) Vaccine in the National Immunisation Programme—For Whom, When and Where?

Acta Paediatrica, EarlyView.
ABSTRACT The incidence of Tick‐borne encephalitis (TBE) cases has increased. The presumed location of transmission of Tick‐borne encephalitis virus (TBEV) has been expanding increasingly in the western parts of Europe during the past decade. There has also been an increased incidence of surveillance‐reported TBE cases in southern Sweden and southern ...
H. H. Askling, D. Zavadska
wiley   +1 more source

Antigenic Characterization of New Lineage II Insect-Specific Flaviviruses in Australian Mosquitoes and Identification of Host Restriction Factors

Msphere, 2020
The globally important flavivirus pathogens West Nile virus, Zika virus, dengue viruses, and yellow fever virus can infect mosquito vectors and be transmitted to humans and other vertebrate species in which they cause significant levels of disease and ...
J. Harrison, J. Hobson-Peters, Agathe M. G. Colmant, Joanna Koh, N. Newton, D. Warrilow, H. Bielefeldt-Ohmann, Thisun B. H. Piyasena, Caitlin A. O’Brien, Laura J. Vet, Devina Paramitha, James R. Potter, S. Davis, C. Johansen, Y. X. Setoh, A. Khromykh, R. Hall   +16 more
semanticscholar   +1 more source

Ubiquitination dynamics in human tumour viruses: Viral infection, oncogenesis and antiviral therapy

The FEBS Journal, EarlyView.
The ubiquitin system is essential for cellular homeostasis and regulates many processes. Viruses, including oncogenic ones, exploit or evade this system to survive and replicate. This review explores how human tumour viruses manipulate the ubiquitination system to complete their life cycle, evade immunity and promote cancer.
Oscar Trejo‐Cerro, Martina Bergant Marušič, Justyna Broniarczyk   +2 more
wiley   +1 more source

New insights into flavivirus evolution, taxonomy and biogeographic history, extended by analysis of canonical and alternative coding sequences.

PLoS ONE, 2015
To generate the most diverse phylogenetic dataset for the flaviviruses to date, we determined the genomic sequences and phylogenetic relationships of 14 flaviviruses, of which 10 are primarily associated with Culex spp. mosquitoes. We analyze these data,
Gregory Moureau, Shelley Cook, Philippe Lemey, Antoine Nougairede, Naomi L Forrester, Maxim Khasnatinov, Remi N Charrel, Andrew E Firth, Ernest A Gould, Xavier de Lamballerie   +9 more
doaj   +1 more source

Unravelling the biochemical aspects of the interaction between ticks and Leishmania using a tick cell line

Medical and Veterinary Entomology, EarlyView.
Leishmania infantum propagated in IDE8 tick cell line in vitro. L. infantum reduces tick cell viability and induces reactive oxygen species production. Lipidic profile of IDE8 tick cell line is altered during Leishmania infection. Abstract Leishmaniasis comprises a group of vector‐borne neglected tropical diseases caused by species of the obligatory ...
Beatriz Filgueiras Silvestre, Karoline dos Anjos Lima, Fernanda de Paula Pepino, Daniela Cosentino‐Gomes, Adivaldo Fonseca, Lesley Bell‐Sakyi, Georgia Correa Atella, Lucia H. Pinto‐da‐Silva   +7 more
wiley   +1 more source

Sexual transmission of Zika virus and other flaviviruses: A living systematic review

PLoS Medicine, 2018
Background Health authorities in the United States and Europe reported an increasing number of travel-associated episodes of sexual transmission of Zika virus (ZIKV) following the 2015–2017 ZIKV outbreak.
M. Counotte, Caron R Kim, Jingying Wang, K. Bernstein, C. Deal, N. Broutet, N. Low   +6 more
semanticscholar   +1 more source

Posttranslational modifications of heterologous proteins expressed in Nicotiana benthamiana

Plant Biotechnology Journal, EarlyView.
Summary The success of Nicotiana benthamiana as a workhorse for heterologous protein production is closely linked to its accessibility and tolerance to genetic manipulation, allowing efficient engineering of posttranslational protein modifications (PTMs) that are critical for the function and stability of heterologous proteins.
Kathrin Göritzer, Somanath Kallolimath, Richard Strasser   +2 more
wiley   +1 more source