Results 81 to 90 of about 33,331 (204)

Flavivirus Receptors: Diversity, Identity, and Cell Entry

Frontiers in Immunology, 2018
Flaviviruses are emerging and re-emerging arthropod-borne pathogens responsible for significant mortality and morbidity worldwide. The genus comprises more than seventy small, positive-sense, single-stranded RNA viruses, which are responsible for a ...
Mathilde Laureti, Mathilde Laureti, Divya Narayanan, Divya Narayanan, Julio Rodriguez-Andres, Julio Rodriguez-Andres, John K. Fazakerley, John K. Fazakerley, Lukasz Kedzierski, Lukasz Kedzierski   +9 more
doaj   +1 more source

Tick-borne Flaviviruses

, 2003
Tick-borne encephalitis (TBE), one of the most dangerous neuroinfections in Europe and Asia, is caused by tick-borne encephalitis virus (TBEV) and currently involves approximately 11,000 human cases annually, mostly in Russia. This chapter describes the main problems associated with the epidemiology, ecology, pathogenesis, and control of this disease ...
Gritsun, T, Nuttall, P, Gould, E
openaire   +3 more sources

Expression of Purinergic and Endothelial Activation Markers in Brain Tissue From Fatal Microcephaly Associated With ZIKV

Immunity, Inflammation and Disease, Volume 14, Issue 3, March 2026.
ABSTRACT Background Zika virus (ZIKV) is a flavivirus that has gained global attention due to its association with congenital microcephaly and neuroinflammatory responses. Markers of endothelial activation and purinergic signaling have been identified in the context of ZIKV neuropathogenesis, although the underlying mechanisms remain poorly understood.
Jorge Rodrigues de Sousa, Gustavo Batista Ferro, Leticia Vieira Teixeira, Carlos Silva, Ligia Lima, Orlando Neto, Raimunda Azevedo, Jannifer Oliveira Chiang, Livia Medeiros Neves Casseb, Arnaldo Jorge Martins Filho, Lívia Caricio Martins, Juarez Antônio Simões Quaresma, Pedro Fernando da Costa Vasconcelos   +12 more
wiley   +1 more source

Akkermansia muciniphila enhances chicken resistance to infectious bronchitis virus by boosting GABA synthesis and suppressing the NF‐κB inflammatory pathway

iMetaOmics, Volume 3, Issue 1, March 2026.
Infectious bronchitis virus (IBV) represents a major threat to poultry production, with current control strategies offering limited protection. In this study, we demonstrate gut microbiome is a critical determinant of IBV resistance using fecal microbiota transplantation.
Ouyang Peng, Yufang Liu, Xuanci Wang, Yihui Huang, Yiqin Yang, Qixiang Kang, Rui Geng, Guangli Hu, Aiping Lv, Fangyu Hu, Yongbo Xia, Xin Luo, Jiamin Liao, Yihong He, Zhanpeng Kuang, Yunping Du, Yun Zhang, Chunyi Xue, Zongxi Han, Wen‐Jun Li, Lei Dong, Hao Zhang, Yongchang Cao   +22 more
wiley   +1 more source

Non-structural protein-1 is required for West Nile virus replication complex formation and viral RNA synthesis [PDF]

, 2013
BACKGROUND: Flavivirus NS1 is a non-structural glycoprotein that is expressed on the cell surface and secreted into the extracellular space, where it acts as an antagonist of complement pathway activation.
Ambrose, Rebecca L, Diamond, Michael S, Mackenzie, Jason M, Youn, Soonjeon   +3 more
core   +3 more sources

Human Cyclophilins—An Emerging Class of Drug Targets

Medicinal Research Reviews, Volume 46, Issue 2, Page 475-512, March 2026.
ABSTRACT Cyclophilins are a family of enzymes with peptidyl‐prolyl isomerase activity found in all cells of all organisms. To date, 17 cyclophilin isoforms have been identified in the human body, participating in diverse biological processes. Consequently, cyclophilins have emerged as promising targets for drug development to address a wide array of ...
Katarina Jurkova, Hana Navratilova, Kamil Musilek, Ondrej Benek   +3 more
wiley   +1 more source

Langat Virus Biology and Infection

Reviews in Medical Virology, Volume 36, Issue 2, March 2026.
ABSTRACT Flaviviruses pose a major threat to global health and can cause severe disease in animals and humans. Among them, tick‐borne encephalitis virus (TBEV) and related members of the tick‐borne encephalitis (TBE) serocomplex are transmitted primarily by ticks and can lead to neurological disease, including encephalitis and death. Despite many years
Zinaida Klestova, Daniel Sauter, Michael Schindler, Thomas Iftner   +3 more
wiley   +1 more source

New insights into flavivirus evolution, taxonomy and biogeographic history, extended by analysis of canonical and alternative coding sequences.

PLoS ONE, 2015
To generate the most diverse phylogenetic dataset for the flaviviruses to date, we determined the genomic sequences and phylogenetic relationships of 14 flaviviruses, of which 10 are primarily associated with Culex spp. mosquitoes. We analyze these data,
Gregory Moureau, Shelley Cook, Philippe Lemey, Antoine Nougairede, Naomi L Forrester, Maxim Khasnatinov, Remi N Charrel, Andrew E Firth, Ernest A Gould, Xavier de Lamballerie   +9 more
doaj   +1 more source

Mosquito surveillance for prevention and control of emerging mosquito-borne diseases in Portugal - 2008-2014 [PDF]

, 2014
Mosquito surveillance in Europe is essential for early detection of invasive species with public health importance and prevention and control of emerging pathogens.
Alves, M.J., Amaro, F., Osório, H.C., Zé-Zé, Líbia   +3 more
core   +2 more sources

Unravelling Electronic Structure and Molecular Vibrations of Proteins in Virus Using Novel Correlated Plasmon‐Enhanced Raman Spectroscopy With Machine Learning

Small, Volume 22, Issue 14, 6 March 2026.
A novel, non‐destructive, stable, direct technique, named correlated plasmon‐enhanced Raman spectroscopy (CP‐ERS), which is based on a newly‐developed highly oriented single crystalline gold quantum dots (HOSG‐QDs) chip, is developed to measure and quantify molecular vibrations and electronic structure of analytes.
Vashu Kamboj, Shermine Ho, Fakhriedzwan Idris, Donald Heng Rong Ting, Khadijah Bte Kamsari Sanuh, Sylvie Alonso, Eng Soon Tok, Andrivo Rusydi   +7 more
wiley   +1 more source