Results 41 to 50 of about 187,609 (313)

eQTL Meta‐Analysis Reveals Conserved and Population‐Specific Regulatory Variation Underlying Nutritional Trait Evolution and Domestication in Tomato

Advanced Science, EarlyView.
A comprehensive meta‐analysis of expression quantitative trait loci (eQTLs) across five diverse tomato populations reveals a high‐resolution atlas of transcriptional regulation and uncovers conserved and population‐specific regulatory architectures underlying fruit nutritional quality traits, including flavonoids, sugars, organic acids, carotenoids ...
Jiantao Zhao, Xin Wang, Jing Zhang, Ryan McQuinn, Je Min Lee, Itay Gonda, Ari Feder, Yimin Xu, Baike Wang, Qinghui Yu, Denise M. Tieman, Sanwen Huang, Harry Klee, James J. Giovannoni, Zhangjun Fei   +14 more
wiley   +1 more source

Study of Liposomes Containing Extract from the Leaves of Protium heptaphyllum (Aubl.) March in Animals Submitted to a Mutagenic Model Induced by Cyclophosphamide

Biology
Cyclophosphamide (CPA) is an alkylating agent used as a chemotherapy agent in the treatment of cancer, but it has immunosuppressive effects. Protium heptaphyllum (P.
Naiéle Sartori Patias, Valéria Dornelles Gindri Sinhorin, Ana Júlia Lopes Braga Ferneda, João Maurício Andrade Ferneda, Marina Mariko Sugui, Stela Regina Ferrarini, Gisele Facholi Bomfim, Joaz Wellington Lopes, Nadia Aline Bobbi Antoniassi, Larissa Cavalheiro, Nelson Luís de Campos Domingues, Adilson Paulo Sinhorin   +11 more
doaj   +1 more source

Insights into Molecular Interaction of Flavonoid Compounds in Citrus Peel Bound to Collagenase and Elastase Enzymes: A Computational Study

Pharmaceutical Sciences and Research, 2021
Citrus peels contain various phytochemical active compounds such as flavonoids that are useful for antiaging cosmetic products. This study was conducted to identify the anti-collagenase and anti-elastase activities of flavonoid compounds in citrus peel ...
Sani Ega Priani, Taufik Muhammad Fakih
doaj   +1 more source

Flavonoid-based cancer therapy

, 2019
Figure 1. All of the flavonoids subgroups have a basic chemical structure formed from two benzene rings, which have been connected by a 3‐carbon bond and finally shape a heterocycle (C6-C3-C6).Figure 2.
Ali Hassanzadeh (6924581)
core   +1 more source

Icariin Enhances the Enzymatic Activity of N‐acetylgalactosaminidase to Augment Akkermansia Abundance in Gut Microbiota for Improved PD‐1 Blockade Efficacy in Tumor Suppression

Advanced Science, EarlyView.
Icariin promoted the growth of Akk by enhancing the activity of N‐acetylgalactosaminidase (Amuc_0920), which enhanced mucin utilization and provided a favorable nutrient environment for bacterial growth. This icariin‐mediated enrichment of Akk further reshaped the tumor microenvironment and promoted CD8+ T cell infiltration, ultimately synergizing with
Shuangying Qiao, Liu Yang, Haibang Hao, Qiuxia Ding, Feng Ding, Zheng Chen, Jinfang Zhang, Yun He, Meng Li, Jun Xu, Chao Wang, Aiping Lu, Fangfei Li   +12 more
wiley   +1 more source

Neurotransmitter Availability and Anti-Inflammatory and Antioxidant Effects of Subacute Administration of Aloysia gratissima (Gillies & Hook) Tronc. and Rutin in Female Wistar Rats

BioChem
Background: Levels of chronic inflammation, oxidative stress, and neurotransmitter availability are altered in depressed patients and can be used as biological markers.
Gênifer Erminda Schreiner, Elizandra Gomes Schmitt, Gabriela Escalante Brittes, Laura Smolski dos Santos, Luana Tamires Maders, Itamar Luís Gonçalves, Sílvia Muller de Moura Sarmento, Nessana Dartora, Vanusa Manfredini   +8 more
doaj   +1 more source

Integration of Spatiotemporal Multi‐Omics in Peach Fruit Unravels a Metabolic Niche and the Genetic Basis of Trichome‐Mediated Stress Adaptation

Advanced Science, EarlyView.
This study constructed the first spatiotemporal multi‐omics map of peach fruit and discovered a key candidate gene that synergistically regulates trichome development and drought tolerance through the jasmonic acid signaling pathway, providing insights into the coupling mechanism between development and stress resistance.
Zhixin Liu, Ke Cao, Liping Guan, Aizhi Qin, Yong Li, Zihao Zhao, Yinpeng Zhang, Yaping Zhou, Lirong Wang, Xuwu Sun   +9 more
wiley   +1 more source

Flavonoids [PDF]

Advances in Nutrition, 2013
Diane F, Birt, Elizabeth, Jeffery
  +5 more sources

The BnTFL1‐BnJAM3‐BnSWEETs Module Orchestrates Seed Storage Reserve Accumulation in Brassica napus

Advanced Science, EarlyView.
BnaC03.TFL1 and BnaA01.JAM3 form a complex that facilitates the transport of soluble sugars from the seed coat to the embryo by directly activating the expression of BnSWEETs. Furthermore, BnaC03.TFL1 and BnaA01.JAM3 work cooperatively to promote soluble sugar and oil production while suppressing protein deposition.
Jianjun Wang, Zijin Liu, Minshan Jin, Junting Liu, Shihao Wei, Dengmao Yang, Saiqi Yang, Yuan Guo, Mingxun Chen   +8 more
wiley   +1 more source

Melanoxetin: A Hydroxylated Flavonoid Attenuates Oxidative Stress and Modulates Insulin Resistance and Glycation Pathways in an Animal Model of Type 2 Diabetes Mellitus

Pharmaceutics
Type 2 diabetes mellitus (DM) continues to escalate, necessitating innovative therapeutic approaches that target distinct pathways and address DM complications.
Sónia Rocha, Andreia Amaro, Marcos D. Ferreira-Junior, Carina Proença, Artur M. S. Silva, Vera M. Costa, Sara Oliveira, Diogo A. Fonseca, Sónia Silva, Maria Luísa Corvo, Marisa Freitas, Paulo Matafome, Eduarda Fernandes   +12 more
doaj   +1 more source