Results 71 to 80 of about 70,065 (302)

Sulfated Cyclocarya Paliurus Polysaccharide Sorchestrates the Gut Microbiome to Mobilize a Host‐Derived 12‐HEPE Against Ulcerative Colitis

Advanced Science, EarlyView.
A sulfated polysaccharide (SCP) from Cyclocarya paliurus alleviates ulcerative colitis by reshaping the gut microbiome. This remodeled microbiota orchestrates the upregulation of the host‐derived lipid 12‐HEPE, which directly inhibits the TLR4/NF‐κB pathway to suppress inflammation.
Xianxiang Chen, Mingyue Shen, Rui Zhang, Zhibing Huang, Hui Niu, Qiang Yu, Yi Chen, Xiangwen Pan, Liyuan Rong, Huiliang Wen, Jun Yang, Jianhua Xie   +11 more
wiley   +1 more source

Transcriptome and metabolome analysis reveals the effects of fatty acid degradation on flavonoid biosynthesis in apple

Fruit Research
In flavonoid biosynthesis, the phenylpropanoid branch has received increasing attention, but little attention has been paid to the fatty acid β-oxidation branch involved in providing the necessary malonyl-Coenzyme A (CoA) moieties of flavonoids. Here, we
Haoliang Wan, Tongtong Wang, Zhongyu Wang, Yuanming Zhou, Mengyao Yang, Kangni Yang, Jiyun Nie   +6 more
doaj   +1 more source

Mechanism of Fruit Ripening - Chapter 16 [PDF]

, 2010
The fruit ripening process has been viewed over the last decades as being successively of physiological, biochemical, and molecular nature. Fruit ripening is accompanied by a number of biochemical events, including changes in color, sugar, acidity ...
Bouzayen, Mondher, Latché, Alain, Nath, Pavendra, Pech, Jean-Claude   +3 more
core   +1 more source

The Flavonoid Biosynthesis and Regulation in Brassica napus: A Review

International Journal of Molecular Sciences, 2022
Brassica napus is an important crop for edible oil, vegetables, biofuel, and animal food. It is also an ornamental crop for its various petal colors. Flavonoids are a group of secondary metabolites with antioxidant activities and medicinal values, and are important to plant pigmentation, disease resistance, and abiotic stress responses. The yellow seed
Yuan-Yuan Chen, Hai-Qin Lu, Kai-Xuan Jiang, Yi-Ran Wang, You-Ping Wang, Jin-Jin Jiang   +5 more
openaire   +2 more sources

NIR‐II‐Trackable LYTACs Phyto‐Nanotheranostics for Source‐Microenvironment Dual‐Track ROS Regulation in Acute Gouty Arthritis

Advanced Science, EarlyView.
The TPR‐LYTACs nanomaterial offers a dual‐pathway strategy for precise gouty arthritis treatment by targeting and degrading the ROS‐producing enzyme NOX2 inside macrophages while its antioxidant core clears accumulated ROS outside. This “source inhibition and microenvironment scavenging” approach, guided by NIR‐II imaging, effectively controls local ...
Jian Zhang, Yingying Wang, Lujie Yu, Chunmei Jiang, Haoyu Liu, Yaohua Chen, Shutong Wu, Qin Liu, Lingling Wei, Xiaochun Zheng, Huifang Hao, Mengting Gao, Weiwei Kang, Rong Dai, Ziliang Zheng, Ruiping Zhang   +15 more
wiley   +1 more source

Heat Shock Protein 90: From Molecular Chaperone Function to Therapeutic Targeting in Malignancies

Advanced Science, EarlyView.
In this review, an integrated conceptual framework linking HSP90's molecular chaperone functions to its pathological roles in cancer is proposed. HSP90 serves as a central node that integrates oncogenic signaling, buffers proteotoxic stress, maintains cancer stem cell plasticity, and shapes tumor‐immune interactions, all of which converge to drive ...
Beibei Zhang, Xinxin Zou, Jiansong Zhou, Qinmiao Sun, Dahua Chen   +4 more
wiley   +1 more source

Transcriptome‐Wide Association Analysis of Flavonoid Biosynthesis Genes and Their Correlation With Leaf Phenotypes in Hawk Tea (Litsea coreana var. sinensis)

Ecology and Evolution
Hawk tea (Litsea coreana var. sinensis), derived from the tender shoots or leaves, rich in flavonoids can promote healthcare for humans. The primary flavonoid are kaempferol‐3‐O‐β‐D‐glucoside, kaempferol‐3‐O‐β‐D‐galactoside, quercetin‐3‐O‐β‐D‐glucoside ...
Lan Yang, Huie Li, Na Xie, Gangyi Yuan, Qiqiang Guo   +4 more
doaj   +1 more source

Topical Application of Ethanol Extract of Starfruit Leaves (Averrhoa Bilimbi Linn) Increases Fibroblasts in Gingival Wounds Healing of White Male Rats [PDF]

, 2012
Injuries to the gingiva are often encountered because of abnormalities in the oral cavity. Gingival wound healing is more complex because it lies in an open area, often contaminated and exposed to various types of bacteria in the oral cavity.
Hartini, I. (IGAA)
core   +2 more sources

Optimizing Oleaginous Yeast Cell Factories for Flavonoids and Hydroxylated Flavonoids Biosynthesis [PDF]

ACS Synthetic Biology, 2019
Plants possess myriads of secondary metabolites with a broad spectrum of health-promoting benefits. To date, plant extraction is still the primary route to produce high-value natural products which inherently suffers from economics and scalability issues.
Yongkun Lv, Monireh Marsafari, Mattheos Koffas, Jingwen Zhou, Peng Xu   +4 more
openaire   +2 more sources

Resistant Peanut Genotype Reprograms Rhizosphere Metabolism to Enhance Bacterial Wilt Suppression

Advanced Science, EarlyView.
The resistant peanut genotype selectively recruits beneficial bacteria, which coincides with the activation of salicylic acid (SA)‐dependent systemic acquired resistance (SAR) against Ralstonia solanacearum. Keystone rhizosphere metabolites are positively correlated with both beneficial microbiome assembly and SAR gene expression.
Rui Ren, Xiaogang Li, Hao Li, Zenghui Cao, Mengtian Hou, Chunlei Zhao, Nan Lou, Sasa Hu, Yanzhe Li, Qian Ma, Yaoyao Li, Yi Fan, Kunkun Zhao, Kai Zhao, Ding Qiu, Fangping Gong, Zhongfeng Li, Haitao Liu, Xingli Ma, Xingxiang Wang, Dongmei Yin   +20 more
wiley   +1 more source