Results 81 to 90 of about 26,547 (202)
The WHO Classification of Genetic Tumour Syndromes: Considerations for Genetics
The WHO Classification of Tumours underpins the diagnosis of neoplastic conditions. The new WHO classification of genetic tumour syndromes (GTS) provides international standards for their diagnosis. This diagram highlights the chromosomal distribution of the genes involved in the GTS covered in this classification.
Ian A. Cree +18 more
wiley +1 more source
A Comparative Biochemical Study of Oleate Hydratases
Four oleate hydratases (Ohys) from diverse homologous families (HFams) were characterized side‐by‐side in terms of expression levels, oligomeric state, flavin adenine dinucleotide (FAD) affinity, thermostability, and activity. A general favorable effect of the reduction of FAD to FADH2 for Ohy activity was demonstrated, with (R)‐10‐hydroxystearic acid (
Maxim van Delft +3 more
wiley +1 more source
A physics‐grounded framework based on decoherence timescales (τ_dec vs τ_func), Markovian validity, and falsifiability criteria is applied across molecular systems to distinguish where quantum effects are necessary, marginal, or irrelevant. The analysis integrates quantum chemistry, biological quantum mechanisms, and quantum computing under a unified ...
Sarfaraz K. Niazi
wiley +1 more source
ERβ activation restores glucose and lipid homeostasis by remodeling the hepatic lipidome. Mechanistically, it promotes complete fatty acid oxidation and decreases Acetyl‐CoA levels, leading to reduced ketogenesis and lipotoxicity, as demonstrated through in vivo and in vitro approaches.
Debora Santos Rocha +9 more
wiley +1 more source
ABSTRACT Objectives It is well known that Porphyromonas gingivalis, a major pathogen in periodontitis, causes systemic diseases. This study investigated the expression of PGC‐1α (the most important factor in muscle mitochondria synthesis) following endurance training to clarify the relationship between P.
Kairi Hayashi +6 more
wiley +1 more source
ABSTRACT BorF is a short‐chain flavin reductase from a desert soil bacterium that uses NADH to reduce FAD to FADH2, which is used by the tryptophan‐6‐halogenase BorH to chlorinate tryptophan in the biosynthetic pathway of borregomycin A. The X‐ray crystal structure of BorF bound to FAD was solved to 2.37 Å by molecular replacement.
Zheng Ma +3 more
wiley +1 more source
Bacillus proteolyticus OA7, isolated from textile wastewater, efficiently removed Acid Red 88 (69.74%) and Acid Blue 193 (41.01%) through substrate‐dependent mechanisms. Acid Red 88 removal involved both biosorption and biodegradation, whereas Acid Blue 193 was mainly biosorbed. FT‐IR revealed functional group changes associated with EPS, proteins, and
Safiye Elif Korcan +5 more
wiley +1 more source
‘Seeing’ the electromagnetic spectrum: spotlight on the cryptochrome photocycle
Cryptochromes are widely dispersed flavoprotein photoreceptors that regulate numerous developmental responses to light in plants, as well as to stress and entrainment of the circadian clock in animals and humans.
Blanche Aguida +14 more
doaj +1 more source
Life on Mars? The physiological perspective
Experimental Physiology, EarlyView.
Ronan M. G. Berg, Damian M. Bailey
wiley +1 more source
Anaerobic biodegradation of benzene by sulphate‐reducing strain BzS1 was studied by combining genomics, differential proteomics and targeted metabolite analyses. Strain BzS1 has an exceptionally streamlined metabolism. A highly abundant heterotrimeric flavoprotein may add benzene to either enolpyruvate or glutaconyl‐CoA followed by channelling into the
Florin Musat +11 more
wiley +1 more source

