Results 101 to 110 of about 29,105 (237)

Identification of stable normalization genes for quantitative real-time PCR in porcine articular cartilage

Journal of Animal Science and Biotechnology, 2012
Background Expression levels for genes of interest must be normalized with an appropriate reference, or housekeeping gene, to make accurate comparisons of quantitative real-time PCR results.
McCulloch Ryan S, Ashwell Melissa S, O’Nan Audrey T, Mente Peter L   +3 more
doaj   +1 more source

Deciphering Cold Stress Resilience: Multiomics Insights in Contrasting Wheat Genotypes From the Western Himalayas

Plant Biotechnology Journal, EarlyView.
ABSTRACT Cold stress threatens wheat productivity, particularly in regions with extreme climatic conditions. To elucidate the molecular mechanisms underlying wheat's response to cold stress, we performed a multiomics analysis integrating lipidomics, transcriptomics, proteomics and metabolomics.
Sofora Jan, Farkhandah Jan, Mukesh Rathore, Yogita Singh, Prexha Kapoor, Palak Chaturvedi, Arindam Ghatak, Palakurthi Ramesh, Upendra Kumar, Manoj Prasad, Sundeep Kumar, Sachin Rustgi, Wolfram Weckwerth, Sanjay Kalia, Rajeev Kumar Varshney, Reyazul Rouf Mir   +15 more
wiley   +1 more source

Systematic Assessment of Uncoupling in Flavoprotein Oxidases and Monooxygenases

, 2021
Flavin as a cofactor is an extremely versatile molecule that participates in a wide range of biochemical reactions. A special characteristic of the flavin cofactor, unique for a metal free cofactor, is its ability to react in its reduced form with ...
Alejandro Gran-Scheuch (5526992), Loreto Parra (5526995), Marco W. Fraaije (1642837)   +2 more
core   +1 more source

Lysine Biosynthesis Defines a Metabolic Checkpoint for Gibberellin‐Mediated Growth in Arabidopsis thaliana

Plant, Cell &Environment, EarlyView.
ABSTRACT Lysine represents a metabolic hub linking mitochondrial energy status with amino acid catabolism, yet its role in coordinating plant growth and development remains poorly characterised. The dapat mutant, which is deficient in L,L‐diaminopimelate aminotransferase (DAPAT), exhibits severe growth inhibition associated with broad metabolic ...
Débora Gonçalves Gouveia, Wesley E Bhering Barrios, Auxiliadora Oliveira Martins, João Henrique Cavalcanti, Laíse Rosado‐Souza, João Antonio Siqueira, Danilo de Menezes Daloso, Alisdair R. Fernie, Adriano Nunes‐Nesi, Andreas P. M. Weber, Wagner L. Araújo   +10 more
wiley   +1 more source

Mechanisms underlying metabolic and neural defects in zebrafish and human multiple acyl-CoA dehydrogenase deficiency (MADD).

PLoS ONE, 2009
In humans, mutations in electron transfer flavoprotein (ETF) or electron transfer flavoprotein dehydrogenase (ETFDH) lead to MADD/glutaric aciduria type II, an autosomal recessively inherited disorder characterized by a broad spectrum of devastating ...
Yuanquan Song, Mary A Selak, Corey T Watson, Christopher Coutts, Paul C Scherer, Jessica A Panzer, Sarah Gibbs, Marion O Scott, Gregory Willer, Ronald G Gregg, Declan W Ali, Michael J Bennett, Rita J Balice-Gordon   +12 more
doaj   +1 more source

Photoinduced monooxygenation involving NAD(P)H-FAD sequential single-electron transfer

Nature Communications, 2020
The number of usable light-responsive enzymes is limited, despite the potential biotechnological applications. Here, the authors report a flavoprotein monooxygenase which is controllable by blue light illumination, and propose a mechanism involving ...
Simon Ernst, Stefano Rovida, Andrea Mattevi, Susanne Fetzner, Steffen L. Drees   +4 more
doaj   +1 more source

Metabolic and neuronal origins of the intrinsic flavoprotein signal response.

, 2016
(A) Mean flavoprotein signal amplitude of the light phase (black) and dark phase (gray) from the GL (solid) and EPL (dash) upon treatment with 10 μM DPI.
Cedric R. Uytingco (3371243), Adam C. Puche (266747), Steven D. Munger (266748)   +2 more
core   +1 more source

The growing VAO flavoprotein family [PDF]

, 2008
The VAO flavoprotein family is a rapidly growing family of oxidoreductases that favor the covalent binding of the FAD cofactor. In this review we report on the catalytic properties of some newly discovered VAO family members and their mode of flavin ...
Heuts, D.P.H.M., Leferink, Nicole G.H., Leferink, Nicole G.H.,, Leferink, Nicole G. H., Fraaije, M.W., van Berkel, W.J.H., Berkel, W.J.H., van, Heuts, Dominic P.H.M.,, Berkel, Willem J.H. van,, Leferink, N.G.H., Fraaije, Marco W., Fraaije, Marco W.,, van Berkel, Willem J. H., Heuts, Dominic P.H.M., Heuts, Dominic P. H. M., van Berkel, Willem J.H.   +15 more
core   +1 more source

Flavoprotein signal profile in the glomerular and external plexiform layers.

, 2016
(A) (top) Flavoprotein response at 2.5s post-stimulus initiation. ONL, olfactory nerve layer; GL, glomerular layer; EPL, external plexiform layer; MCL, mitral cell layer; IPL, internal plexiform layer; GrL, granule cell layer; R, rostral; C, caudal ...
Cedric R. Uytingco (3371243), Adam C. Puche (266747), Steven D. Munger (266748)   +2 more
core   +1 more source

Skeletal muscle‐specific myostatin overexpression promotes muscle oxidative capacity and fatigue resistance in transgenic mice

Experimental Physiology, EarlyView.
Abstract In addition to controlling muscle mass, myostatin may support oxidative metabolism and endurance. Loss of function through gene knockout or post‐natal blockade generally lowers muscle oxidative capacity and increases fatigability. These observations imply that myostatin activation could promote a more oxidative and less fatigable muscle ...
Andy V. Khamoui, Andrea Abraham, Janos Porszasz, Istvan Kovanecz, Silvana Constantinescu, Harry B. Rossiter, Suzanne Reisz‐Porszasz   +6 more
wiley   +1 more source