Results 111 to 120 of about 29,105 (237)

Antioxidant supplementation blunts the proteome response to 3 weeks of sprint interval training preferentially in human type 2 muscle fibres

The Journal of Physiology, EarlyView.
Abstract figure legend Sprint interval training (SIT) is a popular time‐efficient type of endurance training. Healthy young men performed nine SIT sessions (4–6 × 30 s all‐out cycling sprints) over 3 weeks while being supplemented with antioxidants (high doses of vitamins C and E) or placebo. Muscle biopsies taken before and after the first SIT session
Victoria L. Wyckelsma, Marta Murgia, Sigitas Kamandulis, Stefano Gastaldello, Marius Brazaitis, Audrius Snieckus, Nerijus Eimantas, Mati Pääsuke, Sebastian Edman, William Apro, Daniel C. Andersson, Håkan Westerblad, Tomas Venckunas   +12 more
wiley   +1 more source

Vitamin‐Responsive Disorders: From Molecular Basis to Clinical Presentation and Therapy

Journal of Inherited Metabolic Disease, Volume 49, Issue 4, July 2026.
ABSTRACT Vitamin‐dependent cofactors are essential for numerous metabolic reactions, and defects affecting their uptake, conversion, utilisation, or regeneration constitute a heterogeneous group of inherited metabolic disorders (IMDs). Although dietary vitamin intake is sufficient to sustain coenzyme synthesis in healthy individuals, it is insufficient
Cécile Acquaviva, Yann Nadjar, Manuel Schiff, Christine Vianey‐Saban, Alain Fouilhoux, Jean‐François Benoist   +5 more
wiley   +1 more source

Unfolding intermediate in the peroxisomal flavoprotein D-amino acid oxidase of Rhodotorula gracilis

, 2004
A "molten globule"-like intermediate in the unfolding of the peroxisomal flavoprotein D-amino acid ...
CALDINELLI, LAURA, BONOMI F, F. Bonomi, M. Pilone, FERRANTI, PASQUALE, IAMETTI, STEFANIA, L. Piubelli, S. Iametti, POLLEGIONI, LOREDANO, PIUBELLI, LUCIANO, FERRANTI P, BARBIROLI A, PILONE, MIRELLA, PICARIELLO G, BARBIROLI, ALBERTO GIUSEPPE, A. Barbiroli, BONOMI, FRANCESCO, IAMETTI S, M. S. Pilone, L. Caldinelli, L. Pollegioni, G. Picariello, P. Ferranti   +22 more
core   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, Volume 16, Issue 6, Page 1166-1180, June 2026.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

The electron transfer flavoprotein: Ubiquinone oxidoreductases

, 2010
Electron transfer flavoprotein:ubiqionone oxidoreductase (ETF-QO) is a component of the mitochondrial respiratory chain that together with electron transfer flavoprotein (ETF) forms a short pathway that transfers electrons from 11 different mitochondrial
Watmough, Nicholas J., Nicholas J. Watmough, Frerman, Frank E., Frank E. Frerman   +3 more
core   +1 more source

Nature's Nanotech Warriors: The Role of Metalloproteins and Protein Cages for Environmental Remediation

Advanced Sustainable Systems, Volume 10, Issue 6, June 2026.
Cartoon representation of five major classes of metalloproteins and their brief mechanisms of bioremediation. The five classes include metallothioneins, metal‐precipitating enzymes, P.‐type ATPases, protein cages, and synthetic metalloproteins (de novo‐designed proteins/peptides for selective adsorption). These natural and engineered protein structures
Sian D'Silva, Celin Acharya, Soumyananda Chakraborti   +2 more
wiley   +1 more source

Wave Mechanics of Ciliary Proteins: Quantum‐Enabled Sensing and Energy Transfer in the “Cellular Antenna”

Aggregate, Volume 7, Issue 6, June 2026.
This review surveys eukaryotic cilia as putative quantum‐enabled sensory and regulatory centers. It highlights their multifaceted roles in the cell, focuses on the nontrivial roles of quantum mechanics in their membrane and cytoskeletal proteins, and introduces the essential building blocks enabling quantum properties to survive in the warm, wet, and ...
Daniel L. Bilezikian, Dylan Davidoff, Justin R. Caram, Thomas P. Fay, Aarat P. Kalra, Paul S. Weiss   +5 more
wiley   +1 more source

Pro‐ and Anti‐Inflammatory Macrophages Adjust UCP2 Protein Levels Based on Their Intrinsic Metabolism and Available Metabolites

European Journal of Immunology, Volume 56, Issue 6, June 2026.
LPS‐stimulated macrophages exhibit high glycolytic flux, with pyruvate preferentially converted to lactate even under normoglycemic conditions, limiting pyruvate availability for the tricarboxylic acid (TCA) cycle and reducing oxygen consumption rate (OCR).
Jila Nasirzade, Felix Sternberg, Andrea Vogel, Roko Sango, Taraneh Beikbaghban, Thomas Kolbe, Thomas Rattei, Thomas Weichhart, Elena E. Pohl   +8 more
wiley   +1 more source

‘Seeing’ the electromagnetic spectrum: spotlight on the cryptochrome photocycle

Frontiers in Plant Science
Cryptochromes are widely dispersed flavoprotein photoreceptors that regulate numerous developmental responses to light in plants, as well as to stress and entrainment of the circadian clock in animals and humans.
Blanche Aguida, Jonathan Babo, Soria Baouz, Nathalie Jourdan, Maria Procopio, Mohamed A. El-Esawi, Dorothy Engle, Stephen Mills, Stephan Wenkel, Alexander Huck, Kirstine Berg-Sørensen, Sotirios C. Kampranis, Justin Link, Margaret Ahmad, Margaret Ahmad   +14 more
doaj   +1 more source

Chemical aspects of amine oxidation by flavoprotein enzymes

, 2004
The mechanism of amine oxidation by flavoprotein enzymes is critically analysed through analysis of available experimental data. The review assesses available evidence for radical and polar mechanisms, drawing on data from model reactions, kinetic and ...
Scrutton, Nigel S., Nigel S. Scrutton
core   +1 more source