Results 91 to 100 of about 10,862,036 (305)

Adjunctive Therapeutic Plasma Exchange in Refractory Adult‐Onset Still's Disease Complicated by Secondary Macrophage Activation Syndrome: A Single‐Center Experience

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Adult‐onset Still's disease (AOSD) complicated by macrophage activation syndrome (MAS) carries substantial mortality. The role of therapeutic plasma exchange (TPE) remains uncertain. Methods We retrospectively analyzed patients with AOSD‐MAS treated with TPE at a single‐center.
Masataka Ueda, Tomohiro Saito, Masahide Mizobuchi, Tomoki Shimomura, Saki Kawamori, Mitsuru Kawanishi, Natsuko Hattori, Jo Sugiyama, Satoshi Tsubata, Hanami Horiguchi, Kazuki Abe, Nao Iida, Yuki Kajio, Nao Oguro, Ryo Yanai, Hirokazu Honda   +15 more
wiley   +1 more source

Efficient reduced-order modelling based on HODMD to predict intraventricular flow dynamics

Flow
Accurate and efficient modelling of cardiac blood flow is crucial for advancing data-driven tools in cardiovascular research and clinical applications. Recently, the accuracy and availability of computational fluid dynamics methodologies for simulating ...
Eneko Lazpita, Jesús Garicano-Mena, Soledad Le Clainche   +2 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Flow over a cylinder with a small triangular bump

Flow
The surface pressure distribution over a circular cylinder with a small, full-span, triangular bump is examined. The geometry of the bump is an isosceles triangle, the height of which is varied from 1.33 % to 5.33 % of the diameter of the cylinder and ...
Jack Elliott, Alex Nielson, Barton L. Smith   +2 more
doaj   +1 more source

Flow instabilities of magnetic flux tubes II. Longitudinal flow

, 2007
Flow-induced instabilities are relevant for the storage and dynamics of magnetic fields in stellar convection zones and possibly also in other astrophysical contexts.
Achterberg, Achterberg, Achterberg, Andries, Andries, Andries, Cairns, Cheng, D'Silva, D. Schmitt, Ferrari, Ferriz-Mas, Ferriz-Mas, Goossens, Hollweg, Joarder, Kolesnikov, Lashmore-Davies, M. Schüssler, Moreno-Insertis, Moreno-Insertis, Nakariakov, Osin, Parker, Parker, Rae, Ray, Ryutova, Ryutova, Satya Narayanan, Schmitt, Schüssler, Spruit, Spruit, Tirry, V. Holzwarth, Walker   +36 more
core   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Thermally driven cross-shore flows in stratified basins: a review on the thermal siphon dynamics

Flow
The sloping boundaries of stratified aquatic systems, such as lakes, are crucial environmental dynamic zones. While the role of sloping boundaries as energy dissipation hotspots is well established, their contribution to triggering large-scale motions ...
Damien Bouffard, Tomy Doda, Cintia L. Ramón, Hugo N. Ulloa   +3 more
doaj   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Flow distributed oscillation, flow velocity modulation and resonance

, 2005
We examine the effects of a periodically varying flow velocity on the standing and travelling wave patterns formed by the flow-distributed oscillation (FDO) mechanism.
D. A. Care, M. Kærn, M. Menzinger, M. Messerli, M. Messerli, Michael Menzinger, P. V. Kuptsov, Patrick N. McGraw   +7 more
core   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source