Acid-sensing ion channel 3 decreases phosphorylation of extracellular signal-regulated kinases and induces synoviocyte cell death by increasing intracellular calcium. [PDF]
IntroductionAcid-sensing ion channel 3 (ASIC3) is expressed in synoviocytes, activated by decreases in pH, and reduces inflammation in animal models of inflammatory arthritis.
Boyle, David L +6 more
core +2 more sources
A plant-derived glucocorticoid receptor modulator attenuates inflammation without provoking ligand-induced resistance [PDF]
Background: Acquired resistance to glucocorticoids constitutes a major clinical challenge, often overlooked in the search for improved alternatives to classic steroids.
De Bosscher, Karolien +5 more
core +2 more sources
Deep u*- and g-band Imaging of the Spitzer Space Telescope First Look Survey Field : Observations and Source Catalogs [PDF]
We present deep u*-, and g-band images taken with the MegaCam on the 3.6 m Canada-France-Hawaii Telescope (CFHT) to support the extragalactic component of the Spitzer First Look Survey (hereafter, FLS).
Dario Fadda +7 more
core +3 more sources
The Power of Feminist Judgments? [PDF]
Recent years have seen the advent of two feminist judgment-writing projects, the Women’s Court of Canada, and the Feminist Judgments Project in England.
Aileen McColgan +19 more
core +1 more source
Rheumatoid Arthritis Naive T Cells Share Hypermethylation Sites With Synoviocytes. [PDF]
ObjectiveTo determine whether differentially methylated CpGs in synovium-derived fibroblast-like synoviocytes (FLS) of patients with rheumatoid arthritis (RA) were also differentially methylated in RA peripheral blood (PB) samples.MethodsFor this study ...
Barcellos, Lisa F +16 more
core +1 more source
Trial lntern Program Starts; Dean\u27s Day Draws 175 FLS Alumni; Adjunct Prof Investigated After Newspaper\u27s Allegations; Birnbaum, Harper Will Debate ERA; Spring Party Tonighthttps://ir.lawnet.fordham.edu/student_the_advocate/1080/thumbnail ...
The Advocate, Fordham Law School
core +2 more sources
Using Fuzzy Linear Regression Models to Identify the Factors Affecting Myocardial Infarction [PDF]
This study focuses on the application of many fuzzy linear regression models to analyses medical data concerning myocardial infarction, particularly with the level of the troponin, which is vital for identifying heart attacks.
Wafaa Hasanain, Aya Hussein
doaj +1 more source
A two-herb formula inhibits hyperproliferation of rheumatoid arthritis fibroblast-like synoviocytes
Fibroblast-like synoviocytes (FLS) play a pathogenic role in rheumatoid arthritis (RA). STAT3 signaling is activated in FLS of RA patients (RA-FLS), which in turn causes RA-FLS hyperproliferation.
Ying-Jie Chen +14 more
doaj +1 more source
Prevention of osteoporotic refractures in regional Australia [PDF]
Objective: Clinical guidelines recommend that patients who sustain a minimal trauma fracture (MTF) should receive a bone mineral density (BMD) scan and bisphosphonate (or equivalent) therapy if diagnosed with osteoporosis.
Davidson, E +4 more
core +2 more sources
The content and organization of hyaluronan (HA) in the extracellular matrix (ECM) have been identified as strong indicators of inflammation in joint disease, although the source and role of HA as an effector of inflammation is not clear.
Inkyung Kang +11 more
doaj +1 more source

