Results 141 to 150 of about 27,453 (182)

The genetic basis of fluconazole resistance development in Candida albicans

open access: yesBiochimica Et Biophysica Acta - Molecular Basis of Disease, 2002
Infections by the opportunistic fungal pathogen Candida albicans are widely treated with the antifungal agent fluconazole that inhibits the biosynthesis of ergosterol, the major sterol in the fungal plasma membrane. The emergence of fluconazole-resistant
Joachim Morschhauser
exaly   +2 more sources

Emerging fluconazole resistance: Implications for the management of cryptococcal meningitis

open access: yesMedical Mycology Case Reports, 2018
We present the case of an HIV-seropositive individual with cryptococcal meningitis who was found to have a fluconazole resistant strain of Cryptococcus neoformans.
Edward Mpoza   +2 more
exaly   +2 more sources

A systematic review of fluconazole resistance in clinical isolates ofCryptococcusspecies

open access: yesMycoses, 2018
Fluconazole is the most commonly used antifungal agent for both the treatment of cryptococcal meningitis, and for prophylaxis against the disease. However, its prolonged use has the potential to exert selection pressure in favour of fluconazole-resistant
Felix Bongomin   +2 more
exaly   +3 more sources

Fluconazole-Resistant Candida albicans

Clinical Infectious Diseases, 1993
Mucocutaneous candidiasis caused by Candida albicans is a common complication of human immunodeficiency virus (HIV) infection. Recent reports of isolation of resistant strains of C. albicans raise the specter of more widespread resistance, but limited series are available to analyze situations in which the likelihood of resistance is greatest.
D J, Boken, S, Swindells, M G, Rinaldi
openaire   +2 more sources

Fluconazole in combination with flucytosine in the treatment of fluconazole-resistant Candida infections

Diagnostic Microbiology and Infectious Disease, 2003
Two patients with renal failure and fluconazole resistant but flucytosine susceptible Candida deep infection were successfully treated with the combination of the two drugs. In vitro susceptibility, determined by microdilution and time-kill methods, and fungostatic activity of the serum showed an additive interaction of fluconazole and flucytosine.
Corrado Girmenia   +2 more
openaire   +3 more sources

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