Results 121 to 130 of about 40,564 (224)

Fluconazole and Ibuprofen Combination: A Potential Treatment for Mucosal Candidiasis

Medical Laboratory Journal, 2020
Background and objectives: The incidence of drug-resistant candidiasis has increased dramatically. This study aimed to evaluate antifungal effects of fluconazole alone and in combination with ibuprofen on isolates from patients with mucosal candidiasis.  
Tahere Shamoushaki, Leila Fozouni
doaj  

Adaptive Mistranslation Accelerates the Evolution of Fluconazole Resistance and Induces Major Genomic and Gene Expression Alterations in Candida albicans

mSphere, 2017
Regulated erroneous protein translation (adaptive mistranslation) increases proteome diversity and produces advantageous phenotypic variability in the human pathogen Candida albicans.
Tobias Weil, Rodrigo Santamaría, Wanseon Lee, Johan Rung, Noemi Tocci, Darren Abbey, Ana R. Bezerra, Laura Carreto, Gabriela R. Moura, Mónica Bayés, Ivo G. Gut, Attila Csikasz-Nagy, Duccio Cavalieri, Judith Berman, Manuel A. S. Santos   +14 more
doaj   +1 more source

Transcriptome assembly and profiling of Candida auris reveals novel insights into biofilm-mediated resistance [PDF]

, 2018
Candida auris has emerged as a significant global nosocomial pathogen. This is primarily due to its antifungal resistance profile but also its capacity to form adherent biofilm communities on a range of clinically important substrates.
Ben-Ami, Berkow, Berkow, Bizerra, Bongomin, Borman, Borman, Calvo, Chatterjee, Chowdhary, Defosse, Denning, Dominguez, Fisher, Fonseca, Fox, Fu, Grahl, Haas, Hager, Hashemi, Hunter, Jeffery-Smith, Kean, Kean, Kean, Kean, Kempf, Kordalewska, Kordalewska, Larkin, Liu, Liu, Lockhart, Lohse, Martínez, Mukherjee, Naglik, Naglik, Nailis, Nobile, Perfect, Pierce, Rajendran, Rajendran, Rajendran, Ramage, Ramage, Ramage, Rodrigues, Ruiz-Gaitán, Schelenz, Sherry, Sherry, Silva, Soldini, Taff, Taff, Tumbarello, Tunney, Winter, Zarnowski, Zhao, Zhao   +63 more
core   +4 more sources

Preparation and Characterization of Emulsion‐Based Fucoidan‐Whey Protein Film Activated With Geranium Essential Oil for Food Applications

Food Science &Nutrition, Volume 14, Issue 5, May 2026.
The geranium essential oil (EO) nanoemulsion was incorporated into fucoidan‐whey protein film. Active fucoidan‐whey protein film showed higher mechanical, antioxidant, and water barrier properties. Fucoidan‐whey protein film loaded with geranium EO nanoemulsion exhibited antimicrobial and antifungal activities.
Najmeh Oliyaei, Frahang Hameed Awlqadr, Cambyz Irajie, Somayeh Yazdanpanah, Kamyar Zomorodian, Aida Iraji   +5 more
wiley   +1 more source

Mutations in ERG11, TAC1B, and CDR1 reduce fluconazole accumulation in drug-resistant Candidozyma auris isolates

mBio
Fluconazole (FLC)-resistant Candidozyma auris isolates have reduced drug accumulation compared to azole-susceptible isolates. Of 119 C. auris isolates, 83 out of 87 resistant isolates (~95%) had extremely low fluconazole uptake, whereas 30 out of 32 ...
Brooke D. Esquivel, Amanda Santos, Jeffrey M. Rybak, Darian J. Santana, P. David Rogers, Theodore C. White   +5 more
doaj   +1 more source

Antimicrobial use in European acute care hospitals: results from the second point prevalence survey (PPS) of healthcare-associated infections and antimicrobial use, 2016 to 2017 [PDF]

, 2018
Antimicrobial agents used to treat infections are life-saving. Overuse may result in more frequent adverse effects and emergence of multidrug-resistant microorganisms.
Aghdassi, S., Alberg, T., Arendt, V., Arvaniti, K., Asensio, A., Berg, T. C., Berger-Carbonne, A., Borg, M. A., Bosnjak, Z., Budimir, A., Burns, K., Cairns, S., Cantero, M., Daniau, C., Debacker, M., Deptula, A., Dimina, E., Dobreva, E., Dragovac, G., Florentin, D., Gastmeier, P., Gibbons, C., Gudlaugsson, O., Hadjihannas, L., Hajdu, A., Hansen, S., Harrison, W., Hopkins, S., Hopmans, T., Hristova, R., Ivanov, I. N., Jindrak, V., Johnson, A., Karki, T., Kinross, P., Kontopidou, F., Korosec, A., Latour, K., Litvova, S., Lyytikainen, O., Markovic-Denic, L., Martin, P., McConaghy, M., Mitt, P., Monnet, D. L., Moro, M. L., Nedyalkov, M., Neves, I., Niculcea, A. S., Pacheco, P., Plachouras, D., Presterl, E., Quattrocolo, F., Reilly, J., Rydygier, L., Sartaj, M., Sarvikivi, E., Serban, R. I., Smid, E., Staniulyte, J., Stefkovicova, M., Strauss, R., Suetens, C., Vandael, E., Vilde, A., Weist, K., Zarb, P., Zingg, W., Zotti, C. M., Zupanc, T. L.   +69 more
core   +7 more sources

Azole antifungal contaminants disrupt mycorrhizal function and risk agricultural sustainability

PLANTS, PEOPLE, PLANET, Volume 8, Issue 3, Page 952-964, May 2026.
Global food production is increasingly threatened by soil degradation, climate change and the rising costs of synthetic fertilisers. Circular agriculture, which promotes resource reuse, is a promising solution, but using treated wastewater and biosolids in farming introduces risks from emerging contaminants like pharmaceutical residues.
Emily K. Durant, Katie J. Field, J. Brett Sallach, Sara Moeskjær, Alex Williams, Laura J. Carter   +5 more
wiley   +1 more source

Multidrug-resistant Candida glabrata strains obtained by induction of anidulafungin resistance in planktonic and biofilm cells

Brazilian Journal of Pharmaceutical Sciences, 2019
Candida glabrata has emerged as a common cause of serious life-threatening fungal infections, largely owing to their low susceptibility to azole antifungals. Recent guidance indicates the use of echinocandins as the first-choice drug for the treatment of
Camila Hatwig, Eduardo A. Balbueno, Vanessa Z. Bergamo, Bruna Pippi, Alexandre M. Fuentefria, Gustavo P. Silveira   +5 more
doaj   +1 more source

Resistance of Candida species to fluconazole [PDF]

Antimicrobial Agents and Chemotherapy, 1995
J H, Rex, M G, Rinaldi, M A, Pfaller
openaire   +2 more sources

An integrated social and natural sciences case study for the reuse of organic wastes as soil amendments

PLANTS, PEOPLE, PLANET, Volume 8, Issue 3, Page 965-982, May 2026.
Reusing organic waste materials, such as animal manure, as soil amendments reduces water and fertiliser demand, contributing to achieving the Sustainable Development Goals. However, organic wastes may contain contaminants of emerging concern (CECs), posing potential ecosystem and human health risks. Despite the importance of this issue, there is a lack
Felicity C. T. Elder, Jose‐Luis Fajardo‐Escoffié, Laura Carter, Emily K. Durant, Katie J. Field, John Nightingale, Brett Sallach, Andrea‐Lorena Garduño‐Jiménez   +7 more
wiley   +1 more source