Results 111 to 120 of about 2,379,902 (206)

Differentially expressed proteins in fluconazole-susceptible and fluconazole-resistant isolates of Candida glabrata.

Drug discoveries & therapeutics, 2015
The current study aimed to identify the differences presented in the proteome of fluconazole-susceptible isolates of Candida glabrata compared to those with fluconazole-resistant ones. Two-dimensional differential gel electrophoresis was applied to identify proteins that were differentially expressed in fluconazole-susceptible and fluconazole-resistant
Shen, Yinzhong, Zhang, Lijun, Jia, Xiaofang, Zhang, Yongxin, Lu, Hongzhou   +4 more
openaire   +2 more sources

Chronic Recurrent Septic Peritonitis in a Diabetic Dog Caused by Staphylococcus pseudintermedius With Splendore–Hoeppli Reaction (Botryomycosis‐Like/Bacterial Pseudomycetoma)

Veterinary Medicine and Science, Volume 12, Issue 6, November 2026.
Chronic, recurrent septic peritonitis due to Staphylococcus pseudintermedius with Splendore‐Hoeppli reaction can be challenging to eradicate, particularly in the presence of diabetes mellitus, and the regional antimicrobial delivery may be considered as a salvage strategy when source control and systemic therapy alone are insufficient.
Diamond Taylor, Kyle L. Granger, Anne Cohen   +2 more
wiley   +1 more source

Mutations in ERG11, TAC1B, and CDR1 reduce fluconazole accumulation in drug-resistant Candidozyma auris isolates

mBio
Fluconazole (FLC)-resistant Candidozyma auris isolates have reduced drug accumulation compared to azole-susceptible isolates. Of 119 C. auris isolates, 83 out of 87 resistant isolates (~95%) had extremely low fluconazole uptake, whereas 30 out of 32 ...
Brooke D. Esquivel, Amanda Santos, Jeffrey M. Rybak, Darian J. Santana, P. David Rogers, Theodore C. White   +5 more
doaj   +1 more source

Adaptive Mistranslation Accelerates the Evolution of Fluconazole Resistance and Induces Major Genomic and Gene Expression Alterations in Candida albicans

mSphere, 2017
Regulated erroneous protein translation (adaptive mistranslation) increases proteome diversity and produces advantageous phenotypic variability in the human pathogen Candida albicans.
Tobias Weil, Rodrigo Santamaría, Wanseon Lee, Johan Rung, Noemi Tocci, Darren Abbey, Ana R. Bezerra, Laura Carreto, Gabriela R. Moura, Mónica Bayés, Ivo G. Gut, Attila Csikasz-Nagy, Duccio Cavalieri, Judith Berman, Manuel A. S. Santos   +14 more
doaj   +1 more source

Histone deacetylase inhibitors as venetoclax‐sensitising partners in acute myeloid leukaemia: Mechanisms, pharmacology and translational perspectives

British Journal of Pharmacology, Volume 183, Issue 21, Page 6261-6290, November 2026.
Abstract Venetoclax combined with hypomethylating agents has improved treatment for older or unfit patients with acute myeloid leukaemia (AML), but resistance and relapse remain common. This review analyses the rationale for combining venetoclax with inhibitors of histone deacetylase (HDAC).
Jaebok Lee, Marc Diederich
wiley   +1 more source

Combination of different molecular mechanisms leading to fluconazole resistance in a Candida lusitaniae clinical isolate.

, 2009
International audienceWe report on the underlying molecular mechanisms likely responsible for the high-level fluconazole resistance in a Candida lusitaniae clinical isolate.
Papon, Nicolas, Chapeland-Leclerc, Florence, Favel, Anne, Boisnard, Stéphanie, Chevalier, Virginie, Florent, Martine, Noël, Thierry, Conti, Audrey, Fallague, Karim, da Silva, Bruno, Reboutier, David, Ruprich-Robert, Gwenaël, Gibot-Leclerc, Stéphanie, Chastin, Christiane, Piednoël, Mathieu   +14 more
core   +1 more source

Peer review of the pesticide risk assessment of the active substance Trichoderma gamsii ICC080

EFSA Journal, Volume 24, Issue 11, November 2026.
Abstract The conclusions of the European Food Safety Authority (EFSA) following the peer review of the initial risk assessments carried out by the competent authorities of the rapporteur Member State, Sweden, and co‐rapporteur Member State, Italy, for the pesticide active substance Trichoderma gamsii ICC080 are reported.
European Food Safety Authority (EFSA), Fernando Álvarez, Maria Arena, Domenica Auteri, Sofia Batista Leite, Marco Binaglia, Anna Federica Castoldi, Teresa Chavez Capilla, Arianna Chiusolo, Angelo Colagiorgi, Mathilde Colas, Federica Crivellente, Chloe De Lentdecker, Isabella De Magistris, Julia Fabrega, Gabriella Fait, Franco Ferilli, German Giner Santonja, Varvara Gouliarmou, Alessio Ippolito, Frederique Istace, Dimitra Kardassi, Aude Kienzler, Anna Lanzoni, Roberto Lava, Renata Leuschner, Alberto Linguadoca, Mariano Lopez Romano, Jochem Louisse, Christopher Lythgo, Iris Mangas, Silvia Mazzega, Andrea Mioč, Ileana Miron, Tunde Molnar, Laura Padovani, Vincenzo Padricello, Martina Panzarea, Juan Manuel Parra Morte, Simone Rizzuto, Miguel Santos, Rositsa Serafimova, Rachel Sharp, Csaba Szentes, Anne Theobald, Manuela Tiramani, Adriana Scattareggia Marchese, Giorgia Vianello, Laura Villamar‐Bouza   +48 more
wiley   +1 more source

Fluconazole resistance Candida albicans in females with recurrent vaginitis and Pir1 overexpression [PDF]

, 2015
Background: Some genes may be associated with Candida albicans resistance to azoles. Pir1 gene is described as responsible to induce resistance in C. albicans.
Roudbari, M., Nikoomanesh, F., Nasrollahi, Z., Poor, M.H., Bazl, M.R., Yadegari, M.H., Mohammadi, S.R.   +6 more
core  

Peer review of the pesticide risk assessment of the active substance Trichoderma asperellum ICC012

EFSA Journal, Volume 24, Issue 11, November 2026.
Abstract The conclusions of the European Food Safety Authority (EFSA) following the peer review of the initial risk assessments carried out by the competent authorities of the rapporteur Member State, Sweden, and co‐rapporteur Member State, France, for the pesticide active substance Trichoderma asperellum ICC012 are reported.
European Food Safety Authority (EFSA), Fernando Álvarez, Maria Arena, Domenica Auteri, Sofia Batista Leite, Marco Binaglia, Anna Federica Castoldi, Teresa Chavez Capilla, Arianna Chiusolo, Angelo Colagiorgi, Mathilde Colas, Federica Crivellente, Chloe De Lentdecker, Isabella De Magistris, Julia Fabrega, Gabriella Fait, Franco Ferilli, German Giner Santonja, Varvara Gouliarmou, Alessio Ippolito, Frederique Istace, Dimitra Kardassi, Aude Kienzler, Anna Lanzoni, Roberto Lava, Renata Leuschner, Alberto Linguadoca, Mariano Lopez Romano, Jochem Louisse, Christopher Lythgo, Iris Mangas, Silvia Mazzega, Andrea Mioč, Ileana Miron, Tunde Molnar, Laura Padovani, Vincenzo Padricello, Martina Panzarea, Juan Manuel Parra Morte, Simone Rizzuto, Miguel Santos, Rositsa Serafimova, Rachel Sharp, Csaba Szentes, Anne Theobald, Manuela Tiramani, Giorgia Vianello, Laura Villamar‐Bouza, Adriana Scattareggia Marchese   +48 more
wiley   +1 more source

Mechanisms of fluconazole resistance in Candida parapsilosis clinical isolates

, 2013
Candida parapsilosis is an emerging fungal pathogen and a leading cause of hospital-acquired bloodstream fungal infections. The prophylactic and long-term use of fluconazole, a widely used antifungal, has resulted in an increased prevalence of resistance
Wanamaker, Eileen B.
core