Results 21 to 30 of about 13,152 (241)
Microbiology Spectrum, 2021 The high morbidity and mortality of cryptococcal meningitis is due to the limited range of therapeutic options: only three classes of antifungal drugs are available (polyenes [amphotericin B], azoles [fluconazole], and pyrimidine analogues [flucytosine]).
Feng Yang +6 more
doaj +1 more source
Frontiers in Medicine, 2022 BackgroundCryptococcal meningitis (CM) is a leading cause of adult meningitis in countries with a high burden of HIV. It has remained a significant cause of morbidity and mortality in Africa despite the extensive rollout of HIV antiretroviral therapy ...
Seke G. Y. Muzazu +8 more
doaj +1 more source
Cryptococcal infection of the ventriculoperitoneal shunt in an immunocompetent patient [PDF]
, 2016 Patient: Male, 52 Final Diagnosis: Cryptococcal ventriculoperitoneal shunt infection Symptoms: Confusion • fever • Lethargy Medication: Amphotericin B • Flucytosine Clinical Procedure: Ventriculoperitoneal shunt removal Specialty: Infectious disease ...
Foong, Kap Sum +2 more
core +2 more sources
Wellcome Open Research, 2022 Introduction: Access to and the cost of induction treatment for cryptococcal meningitis (CM) is rapidly changing. The newly-announced price for flucytosine ($0.75 per 500 mg pill) and possibly lower prices for liposomal amphotericin B (AmB-L) create ...
Amir Shroufi +8 more
doaj +1 more source
First Report of Ventriculoperitoneal Shunt Infection due to Cyberlindnera fabianii. [PDF]
, 2015 Fungal infections in the central nervous system (CNS) are associated with significant morbidity and death. Transient fungemia in immunocompetent patients without any other risk factors for fungemia has been suggested as a possible mechanism that may lead
Baghdadi, Jonathan +3 more
core +3 more sources
Metabolites, 2020 We reviewed the licensed antifungal drugs and summarized their mechanisms of action, pharmacological profiles, and susceptibility to specific fungi. Approved antimycotics inhibit 1,3-β-d-glucan synthase, lanosterol 14-α-demethylase, protein ...
Jiří Houšť +2 more
doaj +1 more source
Pitfalls associated with the use of molecular diagnostic panels in the diagnosis of cryptococcal meningitis [PDF]
, 2017 We report the case of a kidney transplantation patient on chronic immunosuppressive therapy presenting with subacute meningitis. The final diagnosis of cryptococcal meningitis was delayed due to 2 false-negative cryptococcal results on a molecular ...
Burnham, Carey-Ann +5 more
core +2 more sources
Adhesive Properties and Sensitivity to Antifungal Drugs of Candida Albicans, Which Are Released From Patients of Gastroenterological Profile with Candidiasis of the Mucosa of the Upper Part of the Digestive Tract [PDF]
, 2016 Candida albicans were released from 146 loci from 89 patients in order to perform the investigation. The fourth stage of contamination by Candida albicans in the scrape from the tongue and candidiasis of the esophagus or /and the stomach during ...
Kushnirenko, I. (Inessa)
core +2 more sources
Treatment of acute cryptococcal meningitis in HIV infected adults, with an emphasis on resource-limited settings [PDF]
, 2018 BACKGROUND: Despite the advent and increasingly wide availability of antiretroviral therapy, cryptococcal meningitis (CM) remains a significant cause of mortality and morbidity amongst individuals with HIV infection in resource-limited settings.
Dedicoat, Martin +3 more
core +1 more source
New Horizons in Antifungal Therapy
Journal of Fungi, 2016 Recent investigations have yielded both profound insights into the mechanisms required by pathogenic fungi for virulence within the human host, as well as novel potential targets for antifungal therapeutics.
Kaila M. Pianalto, J. Andrew Alspaugh
doaj +1 more source