Results 31 to 40 of about 2,218 (130)

Treatment of experimental cryptococcal meningitis with fluconazole: impact of dose and addition of flucytosine on mycologic and pathophysiologic outcome

, 1996
Fluconazole is effective in the therapy of cryptococcal meningitis in patients with AIDS. The optimal dosage of fluconazole and the impact of combination with flucytosine are not known.
Kartalija, M, Kaye, K, Täuber, MG, Tureen, JH, Liu, Q, Elliott, BR, Sande, MA, J. H. Tureen, M. A. Sande, Q. Liu, B. R. Elliott, K. Kaye, M. Kartalija, M. G. Tauber, Täuber, Martin G.   +14 more
core   +1 more source

A Pilot Study Showing Fluconazole and Flucytosine Activities against Candida glabrata are Affected by Low pH: Implications for the Treatment of Recurrent Vulvovaginal Candidiasis

Clinical and Experimental Obstetrics & Gynecology
Background: Candida albicans (C. albicans) and Candida glabrata (C. glabrata) are mainly associated with vulvovaginal candidiasis (VVC). Management of VVC caused by C.
Ziauddin Khan, Suhail Ahmad, Mohammad Asadzadeh   +2 more
doaj   +1 more source

Intratumoral Microbiota in Fueling Cancer and Steering Treatment Response

MedComm, Volume 7, Issue 10, October 2026.
Emerging research underscores the tumor‐specific colonization of microbiota and the role of intratumoral microbiota in cancer development and treatment resistance across multiple malignancies. Here, we provide a systematic review exploring the latest biotechnological advancements for studying low‐abundance intratumoral microbiota, their origins ...
Minhui Xu, Jie Yu, Ying Chen, Shengfang Ge, Lin Ye, Yefei Wang, Yixiong Zhou, Renbing Jia   +7 more
wiley   +1 more source

Formulation and evaluation of flucytosine-loaded nanoemulgel for enhanced antifungal activity through in vitro and in vivo studies

Journal of Applied Pharmaceutical Research
Background: Fungal skin infections constitute a prevalent global health issue, accompanied by increasing resistance to traditional antifungal medications.
Rajat Srivastava, Ajay Kumar Singh Rawat   +1 more
doaj   +1 more source

Symptomatic Cryptococcal Meningitis with Negative Serum and Cerebrospinal Fluid Cryptococcal Antigen Tests

HIV/AIDS: Research and Palliative Care, 2021
Vivien Nanfuka,1,* Mkhoi L Mkhoi,2– 4,* Jane Gakuru,2 Richard Kwizera,2 Joseph Baruch Baluku,5 Felix Bongomin,6,7 David B Meya1,2,6 1Infectious Diseases Unit, Kiruddu National Referral Hospital, Kampala, Uganda; 2Infectious Diseases Institute ...
Nanfuka V, Mkhoi ML, Gakuru J, Kwizera R, Baluku JB, Bongomin F, Meya DB   +6 more
doaj  

Parallel and cross-resistances of clinical yeast isolates determined by susceptibility pattern analysis

GMS Infectious Diseases, 2016
For calculated initial antifungal therapy, knowledge on parallel and cross-resistances are vitally important particularly in the case of multiresistant isolates.
Schmalreck, Arno F., Willinger, Birgit, Idelevich, Evgeny A., Fegeler, Christian, Lass-Flörl, Cornelia, Fegeler, Wolfgang, Becker, Karsten   +6 more
doaj   +1 more source

Antifungal susceptibility of non-albicans Candida spp. isolated from raw milk and human blood in Alborz and Tehran provinces

Iranian Journal of Microbiology, 2020
Background and Objectives: Recent reports indicate high prevalence of fungal infections due to non-albicans Candida spp. which are present in various environments such as raw milk.
Zahra Namvar, Abbas Akhavan Sepahy, Robab Rafiei Tabatabaei, Sassan Rezaie   +3 more
doaj   +1 more source

Antifungal Dispensing in Denmark: Patterns Across Primary Care, Secondary Care, and Over‐the‐Counter Sectors

APMIS, Volume 134, Issue 10, October 2026.
ABSTRACT Fungal infections pose a significant health burden in Denmark. Increasing global antifungal use and emerging antifungal resistance underscore the need for ongoing characterization of national prescribing trends to inform antifungal stewardship.
Aditya K. Gupta, Elizabeth M. Teasell, Gregory Pellegrino, Vasiliki Economopoulos, Ditte M. L. Saunte   +4 more
wiley   +1 more source

Flucytosine-fluconazole cross-resistance in purine-cytosine permease-deficient Candida lusitaniae clinical isolates: indirect evidence of a fluconazole uptake transporter

, 2003
An unusual interaction between flucytosine and fluconazole was observed when a collection of 60 Candida lusitaniae clinical isolates was screened for cross-resistance.
Noël, Thierry, Paumard, Patrick, Villard, Jean, Chastin, Christiane, François, Fabienne, Brèthes, Daniel   +5 more
core   +1 more source

Genetic mechanisms of in vitro-induced flucytosine resistance in Candidozyma auris [PDF]

Клиническая микробиология и антимикробная химиотерапия
Objective. To develop an in vitro model for the development of Candidozyma auris resistance to flucytosine (5-FC) and characterize its associated mutational profile. Materials and Methods. An adaptive laboratory evolution study was performed on seven
Oganesyan E.G., Gusarova K.V., Kovyrshin S.V., Zhuk A.S., Taraskina A.E., Lyubimova A.V., Vasilyeva N.V.   +6 more
doaj   +1 more source