Results 21 to 30 of about 2,218 (130)

Quantitative and qualitative analysis of the antifungal activity of allicin alone and in combination with antifungal drugs. [PDF]

PLoS ONE, 2012
The antifungal activity of allicin and its synergistic effects with the antifungal agents flucytosine and amphotericin B (AmB) were investigated in Candida albicans (C. albicans). C.
Young-Sun Kim, Kyung Sook Kim, Ihn Han, Mi-Hyun Kim, Min Hyung Jung, Hun-Kuk Park   +5 more
doaj   +1 more source

AMBITION-cm : intermittent high dose AmBisome on a high dose fluconazole backbone for cryptococcal meningitis induction therapy in sub-Saharan Africa : study protocol for a randomized controlled trial [PDF]

, 2015
Cryptococcal meningitis (CM) is a leading cause of mortality among HIV-infected individuals in Africa. Poor outcomes from conventional antifungal therapies, unavailability of flucytosine, and difficulties administering 14 days of amphotericin B are key ...
Leeme, Tshepo, Síle F. Molloy, Changalucha, John M., Molefi, Mooketsi, Molloy, Síle F, Meintjes, Graeme, Molloy, Síle F., Goldberg, Drew W, John R. Perfect, Drew W. Goldberg, Kalluvya, Samuel, Cainelli, Francesca, Letang, Emili, Ndhlovu, Chiratidzo E, Perfect, John R, Ndhlovu, Chiratidzo E., Bisson, Gregory P., Miriam Haverkamp, Burton, Rosie, Rosie Burton, Tariro Makadzange, Harrison, Thomas S, Francesca Cainelli, Hope, William, Haverkamp, Miriam, Chiratidzo E. Ndhlovu, Harrison, Thomas S., Jarvis, Joseph N., Chofle, Awilly A, William Hope, Jarvis, Joseph N, Changalucha, John M, Fenner, Lukas, Perfect, John R., Makadzange, Tariro, Joseph N. Jarvis, Tshepo Leeme, Mooketsi Molefi, Nametso Lekwape, Lekwape, Nametso, John M. Changalucha, Emili Letang, Goldberg, Drew W., Lukas Fenner, Bisson, Gregory P, Awilly A. Chofle, Samuel Kalluvya, Thomas S. Harrison, Graeme Meintjes, Chofle, Awilly A., Gregory P. Bisson   +50 more
core   +2 more sources

Antifungal Susceptibility of Saccharomyces cerevisiae Isolated from Clinical Specimens

Pathogens
(1) Background: Despite being considered a non-pathogenic yeast, recently, a growing occurrence of Saccharomyces cerevisiae infections has been noted. There is little knowledge about the drug susceptibility of this species.
Aleksandra Górzyńska, Kamila Kondracka, Agnieszka Korzeniowska-Kowal, Urszula Nawrot   +3 more
doaj   +1 more source

Short-Course Rather Than Low-Dose Amphotericin B May Exert Potential Influence on Mortality in Cryptococcal Meningitis Patients Treated With Amphotericin B Plus Flucytosine Alone or in Combination With Fluconazole

Frontiers in Microbiology, 2019
BackgroundThe influence of Amphotericin B (AmB) dose and the addition of fluconazole (Flu) on the AmB + 5-flucytosine (5FC) regimen for cryptococcal meningitis (CM) treatment remain debatable.MethodsA retrospective study was conducted to compare 44 CM ...
Lijun Xu, Lijun Xu, Ran Tao, Ran Tao, Jingjing Wu, Xiahong Dai, Caiqin Hu, Ying Huang, YaoKai Chen, Biao Zhu, Biao Zhu, Jianqin He, Jianqin He   +12 more
doaj   +1 more source

In Vitro Characterization of Twenty-One Antifungal Combinations against Echinocandin-Resistant and -Susceptible Candida glabrata

Journal of Fungi, 2021
This study was designed to analyze the interaction of 21 antifungal combinations consisting of seven major antifungal agents against 11 echinocandin- susceptible and six-resistant C. glabrata isolates. The combinations were divided into five major groups
Hazim O. Khalifa, Hidetaka Majima, Akira Watanabe, Katsuhiko Kamei   +3 more
doaj   +1 more source

In vitro activity of amphotericin B and itraconazole in combination with flucytosine, sulfadiazine and quinolones against Exophiala spinifera. [PDF]

, 2003
Item does not contain fulltextThe combined effects of antifungal and antibiotic drugs against Exophiala spinifera were evaluated in vitro by the chequer-board method, calculated as a fractional inhibitory concentration (FIC) index.
Vitale, R.G., Hoog, G.S. de, Afeltra, J., Rijs, A.J.M.M., Verweij, P.E., R. G. Vitale   +5 more
core   +1 more source

Does DHN-Melanin Always Protect Fungi against Antifungal Drugs? The Fonsecaea/Micafungin Paradigm

Microbiology Research, 2022
Several human pathogenic fungi produce melanin. One of its properties during parasitism is the protection against antifungal drugs. This occurs with the agents of chromoblastomycosis, in which DHN-melanin reduces antifungal susceptibility to terbinafine ...
Rowena Alves Coelho, Maria Helena Galdino Figueiredo-Carvalho, Juliana Vitória dos Santos Silva, Dario Correa-Junior, Susana Frases, Rosely Maria Zancopé-Oliveira, Dayvison Francis Saraiva Freitas, Rodrigo Almeida-Paes   +7 more
doaj   +1 more source

Acquired Flucytosine Resistance during Combination Therapy with Caspofungin and Flucytosine for Candida glabrata Cystitis

, 2016
International audienceTreatment of Candida glabrata cystitis remains a therapeutic challenge, and an antifungal combination using flucytosine is one option. We describe two patients with refractory C.
Quesne, Gilles, Legendre, Christophe, Charlier, Caroline, Lortholary, Olivier, Bachelier-Bassi, Sophie, El Sissy, Carine, Scemla, Anne, Bougnoux, Marie-Elisabeth, Sitterlé, Emilie   +8 more
core   +1 more source

Quantitative and qualitative analyses of the cell death process in Candida albicans treated by antifungal agents. [PDF]

PLoS ONE, 2011
The death process of Candida albicans was investigated after treatment with the antifungal agents flucytosine and amphotericin B by assessing morphological and biophysical properties associated with cell death. C.
Kyung Sook Kim, Young-Sun Kim, Ihn Han, Mi-Hyun Kim, Min Hyung Jung, Hun-Kuk Park   +5 more
doaj   +1 more source

Feasibility and clinical outcomes of routine point‐of‐care screening for opportunistic infections among people with advanced HIV disease in Guyana

HIV Medicine, EarlyView.
Abstract Objectives We evaluated the feasibility and outcomes of implementing comprehensive Point‐of‐care (POC) opportunistic infections (OIs) screening among people with Advanced HIV disease (AHD) in Guyana. Methods We conducted a prospective multicentre cohort study across seven sites between February 2024 and March 2025.
Antonio Camiro‐Zúñiga, Tariq Jagnarine, Divya Shivdas, Lakshmi Narain, Kwesi Vanccoten, Kampta Prashad, Abiola Jacobs, Quacy Grant, Mallika Mootoo, Narissa Lawerence, Suzanne Siebs, Escalada Rainier, Omar Sued, Freddy Perez   +13 more
wiley   +1 more source