Results 71 to 80 of about 13,152 (241)

Comparative Antifungal Activity of Cilofungin (LY121019) against Candida Species, Including Evaluation of Susceptibility Testing Method

Canadian Journal of Infectious Diseases, 1992
The in vitro activity of cilofungin against 100 Candida species was compared with 5-flucytosine. amphotericin B and ketoconazole by two laboratories independently and in a blinded fashion using a macrotitre dilution broth method in saam-f medium ...
Abdul H Chagla, John H Hii, Daryl J Hoban, Andrew E Simor, Santiago Ferro, Evelyn Witwicki, Ruby Poon, Donald E Low   +7 more
doaj   +1 more source

Synthesis and Biological Evaluation of Novel 2‐(Piperidin‐4‐yl)‐1,2,3,4‐tetrahydroisoquinoline and 2‐(Piperidin‐4‐yl)decahydroisoquinoline Antimycotics

Archiv der Pharmazie, Volume 358, Issue 10, October 2025.
A series of 13 hybrid molecules of both lead structures were prepared using reductive amination as key reaction step. The antimycotic potency of the resulting compounds was evaluated against yeast and mold species. Two compounds showed remarkable potency against several yeasts, and even against Candida krusei.
Marie‐Christin Hain, Monika Klimt, Franz Bracher, Ulrike Binder, Jürgen Krauß   +4 more
wiley   +1 more source

Minimum Inhibitory Concentrations of Anidulafungin as a Potential Predictor of Biocide Susceptibility of Clade 1 Candidozyma (Candida) auris Isolates

MicrobiologyOpen, Volume 14, Issue 5, October 2025.
Our study shows that a decision tree trained on antifungal MIC profiles, especially anidulafungin, can predict how susceptible Candida auris is to triclosan, chlorine, and chlorhexidine. This shows a possible way to cut down on routine biocide testing in infection control surveillance. ABSTRACT Candidozyma (Candida) auris is a multidrug‐resistant yeast
Sidre Erganis, Ayse Seyer, Mubarak Taiwo Mustapha, Meliz Yuvali, Furkan Martli, Sena Algin, Sema Turan Uzuntas, Beyza Yavuz, Alper Dogan, Esra Kılıc, Fusun Kirca, Abdullahi Garba Usman, Elif Ayca Sahin, Cagrı Ergin, Bedia Dinc, Dilber Uzun Ozsahin, Ayse Kalkanci   +16 more
wiley   +1 more source

Repurposing drugs to fast-track therapeutic agents for the treatment of cryptococcosis [PDF]

, 2018
Many infectious diseases disproportionately affect people in the developing world. Cryptococcal meningitis is one of the most common mycoses in HIV-AIDS patients, with the highest burden of disease in sub-Saharan Africa.
Afeltra, Bicanic, Butts, Byrnes, Catterall, Ceballos, Chatterji, Chong, Chrysant, Clinical and Laboratory Standards Institute (CLSI), Clinical and Laboratory Standards Institute (CLSI), Cruz, Cruz, Cumino, Dehdashti, Del Poeta, Dzoyem, Edlind, Espinel-Ingroff, Feldmeier, Gaggi, Hagen, Hong, Hong, Horton, Jarvis, Joffe, Kneale, Lai, Lassègue, Liu, Liu, Loyse, Meiring, Nixon, Oprea, Park, Peiter, Perfect, Prole, Rabjohns, Rajasingham, Rhein, Samantaray, Smith, Spagnuolo, Spitzer, Teng, Téllez-Girón, Zhai, Zhai   +50 more
core   +3 more sources

Safety and efficacy of a feed additive consisting of Saccharomyces cerevisiae NBRC 0203 and Lacticaseibacillus rhamnosus NBRC 3425 as a silage additive for all animal species (EM‐Agriton B.V.)

EFSA Journal, Volume 23, Issue 10, October 2025.
Abstract Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the additive consisting of Saccharomyces cerevisiae NBRC 0203 and Lacticaseibacillus rhamnosus NBRC 3425 when used as a technological additive to improve ensiling of all fresh plant material for all animal species at a proposed minimum ...
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP), Roberto Edoardo Villa, Giovanna Azimonti, Eleftherios Bonos, Henrik Christensen, Mojca Durjava, Birgit Dusemund, Ronette Gehring, Boet Glandorf, Maryline Kouba, Marta López‐Alonso, Francesca Marcon, Carlo Nebbia, Alena Pechová, Miguel Prieto‐Maradona, Ilen Röhe, Katerina Theodoridou, Pier Sandro Cocconcelli, Secundino López, Andrey Yurkov, Montserrat Anguita, Rosella Brozzi, Nicole Bozzi Cionci, Matteo L. Innocenti, Jordi Ortuño, Piera Valeri, Yolanda García‐Cazorla   +26 more
wiley   +1 more source

High dose fluconazole in salvage therapy for HIV-uninfected cryptococcal meningitis. [PDF]

, 2018
BACKGROUND: The 2010 Infectious Diseases Society of America (IDSA) guidelines for management of cryptococcal diseases recommend high dose fluconazole (≥ 800 mg/day), either alone or with other antifungal drugs, as alternative anticryptococcal choices ...
A Loyse, AJ Berry, BH Segal, C Rothe, CH Liao, DA Stevens, E Milefchik, EJ Anaissie, F Menichetti, HS Rehan, Hua-Zhen Zhao, JC Nussbaum, JE Bennett, Jia-Hui Cheng, JN Day, JR Perfect, JR Perfect, KM Gaskell, Li-Ping Huang, Li-Ping Zhu, Ling-Hong Zhou, LP Zhu, M Cogliati, MA Rolfes, MG Netea, MH Nguyen, MN Gamaletsou, MS Saag, N Longley, NE Nierenberg, P Mootsikapun, P Pappas, P Pitisuttithum, PG Pappas, PG Pappas, PG Pappas, R Rajasingham, RD Diamond, RH Haubrich, Rui-Ying Wang, Thomas Stephen Harrison, TJ Walsh, V Pyrgos, WE Dismukes, Xuan Wang, Ying-Kui Jiang   +45 more
core   +1 more source

Flucytosine Monotherapy for Cryptococcosis [PDF]

Clinical Infectious Diseases, 1998
Flucytosine (5-FC) monotherapy for cryptococcosis is not advocated because drug resistance emerges during therapy. Reported documentation of this widely accepted belief is surprisingly scarce. Therefore, we reviewed our experience with 5-FC monotherapy for 27 patients treated between 1968 and 1973.
D R, Hospenthal, J E, Bennett
openaire   +2 more sources

Изучение острой и подострой токсичности субстанции с противогрибковым действием [PDF]

, 2017
В данной работе авторами исследована острая и подострая токсичность субстанции 2-(6-гидроксиметил-9-метил-2-(4-фторфенил)-5Н- пиридо[4',3':5,6]пирано[2,3-d]пиримидин-4-илсульфанил)-1-N- пиперидинилэтанона (производные 4Н-пиридо[4',3':5,6]пирано[2,3-d ...
Датхаев, У.М., Дербисбекова, У.Б., Момбеков, С.Е., Рахимов, К.Д., Шалабай, А.К., Шарапатдин, А.К.   +5 more
core  

HIV-Associated Cryptococcal Meningitis: Bridging the Gap Between Developed and Resource-Limited Settings. [PDF]

, 2016
Cryptococcal meningitis is a major cause of HIV-associated morbidity and mortality worldwide. Most cases occur in low-income countries, where over half of patients die within 10 weeks of diagnosis compared to as few as 10 % of patients from developed ...
Jarvis, Joseph N, Leeme, Tshepo, Tenforde, Mark W, Wake, Rae   +3 more
core   +1 more source

Cerebral Venous Thrombosis:Current Status and Challenges

Brain and Behavior, Volume 15, Issue 9, September 2025.
Our review introduces treatment strategies for short‐term, long‐term, and permanent CVT risk factors, focusing on anticoagulant selection and treatment duration. We also discuss the current status of endovascular therapy for CVT, noting that it remains a challenge due to limited evidence, and more research is needed to optimize this approach.
Wenbo Zuo, Shengcai Chen, Jiashuo Lin, Yan Wan, Fei Cao, Bo Hu   +5 more
wiley   +1 more source