Results 81 to 90 of about 13,152 (241)

Efficacy of Oral Encochleated Amphotericin B in a Mouse Model of Cryptococcal Meningoencephalitis

open access: yesmBio, 2019
Cryptococcus neoformans is an encapsulated yeast responsible for approximately a quarter of a million deaths worldwide annually despite therapy, and upwards of 11% of HIV/AIDS-related deaths, rivaling the impact of tuberculosis and malaria.
R. Lu   +13 more
doaj   +1 more source

Antifungal resistance of candida species isolated from HIV patients in a tertiary care hospital, Mysuru, Karnataka

open access: yesIndian Journal of Dermatology, 2020
Context: Candidiasis still remains as a common opportunistic infection in patients with human immunodeficiency virus (HIV). Drug resistance has become a serious health concern because of indiscriminate usage and dosage.
Umamaheshwari Shivaswamy, M N Sumana
doaj   +1 more source

Promising Cancer Vaccine for Glioblastoma Therapy: A Focus on mRNA Vaccine

open access: yesCancer Medicine, Volume 14, Issue 18, September 2025.
ABSTRACT Background Glioblastoma (GBM) is an aggressive primary brain tumor with poor prognosis and low survival rates. Standard treatments, such as surgery and radiotherapy, are limited by tumor infiltration and resistance. To review current vaccine strategies for GBM, including peptide, virotherapy, cell‐based, and genetic vaccines, with a focus on ...
Sama Barati   +5 more
wiley   +1 more source

Kajian Molekuler Resistensi Candida Albicans Terhadap Antifungi [PDF]

open access: yes, 2014
Candida albicans is one of the species Candida which mostly cause infection in human. Antifungal agent azole, polyene, echinocandin, and flucytosine are commonly used for Candida albicans infection treatment.
Candrasari, D. S. (Damiana)
core   +3 more sources

Sentinel Case of Candida auris in the Western United States Following Prolonged Occult Colonization in a Returned Traveler from India. [PDF]

open access: yes, 2019
Candida auris is an emerging multidrug-resistant yeast with high mortality. We report the sentinel C. auris case on the United States West Coast in a patient who relocated from India.
Crawford, Emily D   +12 more
core   +1 more source

Molecular Fingerprints to Identify Candida Species [PDF]

open access: yes, 2013
A wide range of molecular techniques have been developed for genotyping Candida species. Among them, multilocus sequence typing (MLST) and microsatellite length polymorphisms (MLP) analysis have recently emerged.
Leonardi, Darío   +1 more
core   +4 more sources

Repurposing Mercaptopurine Through Collateral Lethality to Treat Cancers with Somatic RB1–NUDT15 Loss

open access: yesMedComm, Volume 6, Issue 9, September 2025.
In this study, we found the close proximity of NUDT15 and RB1 in terms of chromosome location and exploited the fact that NUDT15 deficiency induces 6MP‐related adverse drug reactions, thus providing a possible collateral lethality (a specific type of synthetic lethality) strategy to treat RB1‐deficient tumors (created with www.biorender.com).
Tao Zhou   +21 more
wiley   +1 more source

In vitro evaluation of antifungal combinations against neurotropic dematiaceous fungi associated with primary cerebral phaeohyphomycosis

open access: yesMicrobiology Spectrum
Primary cerebral phaeohyphomycosis is a life-threatening disease caused by neurotropic dematiaceous fungi. At present, there are no consensus guidelines regarding optimal antifungal therapy in such cases.
Arghadip Samaddar   +6 more
doaj   +1 more source

Resistance of Asian Cryptococcus neoformans serotype A is confined to few microsatellite genotypes.

open access: yesPLoS ONE, 2012
BackgroundCryptococcus neoformans is a pathogenic yeast that causes cryptococcosis, a life threatening disease. The prevalence of cryptococcosis in Asia has been rising after the onset of the AIDS epidemic and estimates indicate more than 120 cases per 1,
Weihua Pan   +19 more
doaj   +1 more source

Clinical efficacy of flucytosine on urinary candidiasis [PDF]

open access: yes, 1988
An antifungal agent (Flucytosine) was used to treat urinary candidiasis in 9 patients who had an indwelling catheter and developed fungal colony counts greater than 10(4).
安本, 亮二   +7 more
core  

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