Results 1 to 10 of about 5,842 (196)

Fludrocortisone Induces Aortic Pathologies in Mice

Biomolecules, 2022
Background and Objective: In an experiment designed to explore the mechanisms of fludrocortisone-induced high blood pressure, we serendipitously observed aortic aneurysms in mice infused with fludrocortisone.
Dien Ye, Congqing Wu, Hui Chen, Ching-Ling Liang, Deborah A. Howatt, Michael K. Franklin, Jessica J. Moorleghen, Samuel C. Tyagi, Estrellita Uijl, A. H. Jan Danser, Hisashi Sawada, Alan Daugherty, Hong S. Lu   +12 more
doaj   +4 more sources

Extreme metabolic alkalosis with fludrocortisone therapy [PDF]

Postgraduate Medical Journal, 1983
Summary We present an unusual case of extreme metabolic alkalosis resulting from severe hypokalaemia caused by unmonitored fludrocortisone therapy. Biochemical aspects of the disorder are discussed, as is the successful treatment with diuretics and potassium replacement.
P. Semple, T. M. Brown, A. Burns
openaire   +5 more sources

Pharmacokinetics of oral fludrocortisone in septic shock [PDF]

British Journal of Clinical Pharmacology, 2016
AimThe combination of hydrocortisone and fludrocortisone improved outcomes in septic shock. However, the specific role of fludrocortisone remains controversial and its pharmacokinetics (PK) has never been investigated in septic shock. This study aimed at characterizing the PK of fludrocortisone in septic shock.MethodsThis was a single‐centre ancillary ...
Eric Bellissant, Eric Bellissant, Andrea Polito, Bruno Laviolle, Bruno Laviolle, Angelo Polito, Noureddine Hamitouche, Noureddine Hamitouche, Jean-Claude Alvarez, Mégane Ribot, Djillali Annane   +10 more
openaire   +6 more sources

Use of fludrocortisone for intradialytic hypotension

Kidney Research and Clinical Practice, 2018
Intradialytic hypotension during dialysis adversely affects a patient's prognosis and increases mortality. We report a case in which intradialytic hypotension that persisted after the administration of midodrine was relieved after the use of ...
Yuri Seo, Soomin Jeung, Sun-myoung Kang, Won Seok Yang, Hyosang Kim, Soon Bae Kim   +5 more
doaj   +4 more sources

Access to fludrocortisone and to hydrocortisone in children with congenital adrenal hyperplasia in the WHO Eastern Mediterranean Region: it takes a village… [PDF]

BMJ Global Health, 2021
Congenital adrenal hyperplasia (CAH), if untreated, carries high morbidity and mortality. A higher incidence of CAH is expected in countries where consanguinity is common, such as in the countries of the WHO Eastern Mediterranean Region (EMRO).
, Asma Deeb, Jean-Pierre Chanoine, Jamal Raza, Amanda Rowlands, Abdulsalam Abu-Libdeh, Asmahane Ladjouze, Rasha T Hamza, Salwa A Musa, Farida Jennane, Bouferoua Fadila, Delileche Hana, Djahlat Larbi, Noumi Mustapha, Haya Alkhayyat, Abdourahman Douksie, Ali Rabbani, Ali Al-Jumaili, Rasha Odeh, Hessa Alkandari, Hala Tfayli, Suleiman Abusrewil, Millad Ghawil, Aisha Al senani, Fawziya Alkhalaf, Abdelhadi Habeb, Noman Ahmad, Omer Elshareef, Mohamed Abdullah, Olivia Al-Hassan, Dima Karah, Mongia Hachicha, Mohammed Alshakka   +32 more
doaj   +2 more sources

Chronic urine acidification by fludrocortisone to treat infectious kidney stones [PDF]

Comptes Rendus. Chimie, 2021
Chronic urinary tract infections by urease-producing bacteria may increase urine pH and promote thereby the formation of recurrent kidney stones made of highly carbonated calcium phosphate apatite and struvite, a magnesium ammonium phosphate.
Lionet, Arnaud, Roger, Camille, Biardeau, Xavier, Daudon, Michel, Letavernier, Emmanuel   +4 more
doaj   +2 more sources

Fludrocortisone in the treatment of hypotensive disorders in the elderly. [PDF]

Heart, 1996
To evaluate tolerance of fludrocortisone in older patients with hypotensive disorders.Prospective case series.Syncope clinic.64 Consecutive patients over 65 years (mean age 80 years) with one or more hypotensive disorders (orthostatic hypotension, vasodepressor carotid sinus syncope, and/or vasodepressor neurocardiogenic syncope.Fludrocortisone in ...
S. J. McIntosh, Rose Anne Kenny, R. M. Hussain, J. Lawson   +3 more
openaire   +4 more sources

Therapeutic experience with fludrocortisone in diabetic postural hypotension. [PDF]

BMJ, 1976
Fourteen patients with diabetic postural hypotension were treated with fludrocortisone for a mean 12 months (range 6-30 months). The mean daily dose of fludrocortisone was 0.2 mg (range 0.1 mg-0.4 mg). Standing systolic and diastolic blood pressures increased significantly (P less than 0.001) after treatment with fludrocortisone and the postural ...
Ian W Campbell, Basil F Clarke, David J. Ewing   +2 more
openaire   +5 more sources

Performance of renin assays in selecting fludrocortisone dose in children with adrenal disorders [PDF]

Endocrine Connections
Children with salt-wasting adrenal insufficiency are managed with glucocorticoid and mineralocorticoid replacement. Measurement of renin activity or concentration alongside blood electrolyte levels is used to monitor the adequacy of mineralocorticoid ...
Timothy J Morris, Andrew Whatmore, Laura Hamilton, Beverly Hird, Eric S Kilpatrick, Lesley Tetlow, Peter Clayton   +6 more
doaj   +2 more sources

Adverse Cardiac Effects of Salt With Fludrocortisone in Hypertension [PDF]

Hypertension, 2001
The effect of salt on blood pressure (BP) is controversial. A more important question is whether salt can produce cardiac target-organ damage, irrespective of its effect on BP. We assessed the effect of salt with fludrocortisone on QT dispersion and echocardiographic left ventricular diastolic function in a prospective interventional
Lim, Pitt O., Farquharson, Colin A. J., Shiels, Paul, Jung, Roland T., Struthers, Allan D., MacDonald, Thomas M.   +5 more
openaire   +6 more sources