Health Technology AssessmentBackground Orthostatic hypotension is a significant drop in blood pressure upon standing upright. It is very common and can result in symptoms such as postural dizziness, fainting and falls.
Helen Mossop +13 more
doaj +3 more sources
Corticosteroids for sepsis and septic shock: a meta-analysis of 18 RCTs with dose-stratified and fludrocortisone subgroup evaluation [PDF]
BMC AnesthesiologyBackground The therapeutic benefit of corticosteroids in managing sepsis and septic shock remains controversial, particularly concerning optimal dosing strategies and the role of adjunctive fludrocortisone.
Lv Ruyuan +3 more
doaj +4 more sources
Impact of COVID‑19 infection on subsequent prescriptions of autonomic dysfunction pharmacotherapy: a nationwide propensity‑score‑matched Cohort study in Japan [PDF]
Annals of MedicineBackground Autonomic dysfunction, including orthostatic hypotension and postural tachycardia syndrome, has emerged as a COVID-19 complication.
Daisuke Miyamori, Masanori Ito
doaj +2 more sources
Efficacy and side effects of long-term treatment strategies of canine primary hypoadrenocorticism [PDF]
Frontiers in Veterinary ScienceBackgroundHypoadrenocorticism (HA) with hyponatremia and hyperkalemia represents primary disease and indicates cortisol and aldosterone insufficiency. Treatment involves replacement of mineralocorticoids and glucocorticoids.
Deborah Anna Dobosz +2 more
doaj +2 more sources
Successful Management of Cerebral Salt‐Wasting Syndrome in a Child With Epileptic Encephalopathy: A Case Report [PDF]
Clinical Case ReportsThis case highlights the integral role of clinical pharmacists in the treatment process and suggests that fludrocortisone can serve as a safe and effective treatment option for CSWS in pediatric patients, especially when standard sodium supplementation ...
Rui Zhang, Yi Deng, Wenjing Li
doaj +2 more sources
Case Report: Type II Bartter syndrome with a novel KCNJ1 variant in a premature neonate presenting with features of salt-wasting congenital adrenal crisis and pseudo-hypoaldosteronism [PDF]
Frontiers in PediatricsIntroductionBartter syndrome (BS) is a rare group of inherited renal tubulopathies. Diagnosis of BS type II is challenging in the neonatal period as its clinical findings and biochemical features may mimic that of adrenal crisis and pseudo ...
Heung-Ching Tsui +7 more
doaj +2 more sources
Fludrocortisone Induces Aortic Pathologies in Mice
Biomolecules, 2022 Background and Objective: In an experiment designed to explore the mechanisms of fludrocortisone-induced high blood pressure, we serendipitously observed aortic aneurysms in mice infused with fludrocortisone.
Dien Ye +12 more
doaj +1 more source
Frontiers in Cardiovascular Medicine, 2022 BackgroundLow-dose steroids are known to increase arterial pressure during septic shock through restoration of vasopressor response to norepinephrine. However, their effects on cardiac performance and ventriculo-arterial coupling (VAC) have never been ...
François Bagate +15 more
doaj +1 more source
Use of Deoxycorticosterone Pivalate by Veterinarians: A Western European Survey
Veterinary Sciences, 2021 This study aims to gather knowledge about the use of deoxycorticosterone pivalate (DOCP) by Western European Veterinarians (WEV) in dogs with typical hypoadrenocorticism.
Rita Rebocho +8 more
doaj +1 more source
Acta Medica Iranica, 2020 Hyperglycemia may associate with improper use of glucocorticoids, impaired insulin function, or both, and is associated with many complications such as hyperlipidemia and Hyperglycemia.
Hamid Reza Reza Jamshidi +1 more
doaj +1 more source